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All Journal Vitalitas Medis : Jurnal Kesehatan Dan Kedokteran
Fadillah Sayuti
Universitas Muhamadiyah Palembang
Health Professions Public Health

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Adenoid Cystic Carcinoma of the Nasal Cavity: A Rare Case Report Fadillah Sayuti
Vitalitas Medis : Jurnal Kesehatan dan Kedokteran Vol. 3 No. 4 (2026): Oktober: Vitalitas Medis : Jurnal Kesehatan dan Kedokteran
Publisher : Lembaga Pengembangan Kinerja Dosen

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62383/vimed.v3i4.3498

Abstract

Background: Adenoid cystic carcinoma (ACC) is an uncommon malignant epithelial neoplasm that most frequently arises from the salivary glands but may rarely occur in the nasal cavity and paranasal sinuses. Its diagnosis can be challenging because of its slow-growing nature, variable clinical presentation, and distinctive histopathological features. Case Presentation: A 41-year-old woman presented with a progressive nasal mass accompanied by unilateral nasal obstruction and intermittent epistaxis. Physical examination revealed a friable mass occupying the nasal cavity. An excisional biopsy was performed for histopathological evaluation. Microscopic examination demonstrated an infiltrative epithelial neoplasm composed of relatively uniform basaloid cells arranged in cribriform, tubular, and solid patterns. The cribriform areas contained pseudocystic spaces filled with eosinophilic basement membrane-like material. The tumor cells showed hyperchromatic nuclei with scant cytoplasm and mild-to-moderate cytological atypia. Perineural invasion was identified. Conclusion: Adenoid cystic carcinoma of the nasal cavity is a rare malignancy that should be considered in the differential diagnosis of an infiltrative nasal mass, particularly when histology demonstrates a characteristic cribriform or tubular architecture with pseudocystic spaces.
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