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All Journal Indonesian Journal of Global Health research Journal of General-Procedural Dermatology & Venereology Indonesia
Priyanto, Olivia Jovina
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Education Health Professions Languange, Linguistic, Communication & Media Medicine & Pharmacology Nursing Public Health

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The effect of bakuchiol in the skin aging process: A systematic review Priyanto, Olivia Jovina; Sugiyanto, Yosef Ferdinand Rahmat; Salim, Darryl Samuel
Journal of General - Procedural Dermatology & Venereology Indonesia Vol. 7, No. 2
Publisher : UI Scholars Hub

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Abstract

Background: With aging, the skin gradually loses its structural and morphological coherence, decreasing its function. With aging and chronic ultraviolet (UV) exposure, the skin becomes thin and loses elasticity, and wrinkles, pigmentation, and texture irregularities appear. Today, people of all ages become interested in the cosmetic industry, aiming to make their skin appropriate to their age or look younger. Bakuchiol is a pure meroterpene phenol found mainly in the seeds of the Indian plant Psoralea corylifolia (babchi). It triggers antioxidant and anti-inflammatory activity and has anti-aging properties like retinol. The study aimed to know the effect of bakuchiol on the skin aging process. Methods: A systematic review of the literature was conducted. Data were collected and synthesized from online databases with the preferred reporting items for systematic reviews and meta-analyses (PRISMA) protocol. Results: More than 125 articles were found, and six studies were selected according to this research. Of the six existing clinical trial studies, all showed that bakuchiol had a beneficial effect on reducing signs of skin aging. Conclusion: Bakuchiol has shown beneficial effects in preventing or reducing signs of skin aging, such as fine lines and wrinkles, loss of elasticity and firmness, dull skin, uneven hyperpigmentation, skin dryness, and texture irregularities, with minimal side effects.
The Effect of Local Anesthesia on Dermatological Actions on Patient Comfort Riyanto, Puguh; Priyanto, Olivia Jovina
Indonesian Journal of Global Health Research Vol 7 No 5 (2025): Indonesian Journal of Global Health Research
Publisher : GLOBAL HEALTH SCIENCE GROUP

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37287/ijghr.v7i5.7018

Abstract

Local anesthesia is commonly used in a variety of dermatological procedures to reduce pain and improve patient comfort. However, some side effects can occur, including burning sensations, nausea, vomiting, dizziness, blurred vision, and even impaired consciousness. This study aimed to evaluate the effect of local anesthesia on patient comfort during dermatological procedures. The study was conducted at an aesthetic clinic in Semarang from 7 to 9 February, involving 20 patients (2 men and 18 women). This study uses a quantitative descriptive study with a cross-sectional approach to assess patient comfort and side effects after local anesthesia in dermatologic procedures. Patients aged 18 and older who consent will be recruited consecutively. Researchers will using observation checklist and vital sign chart to collect demographic and clinical data, observe and record specific side effects such as feeling hot/sore, nausea, vomiting, dizziness, blurred vision, impaired consciousness, and fainting during and up to 30 minutes after the procedure, and monitor vital signs before and after the procedure. The results showed that 16 out of 20 patients reported no complaints after the procedure. Three patients experienced a burning sensation, while one patient experienced nausea and vomiting. None of the patients reported dizziness, blurred vision, loss of consciousness, or fainting. In conclusion, local anesthesia provides a high level of comfort for patients with minimal side effects. Therefore, it remains a safe and effective option for dermatological procedures, although monitoring individual responses remains important.
Co-Authors Darryl Samuel Salim, Darryl Samuel Puguh Riyanto Sugiyanto, Yosef Ferdinand Rahmat