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HUBUNGAN TINGKAT STRES DENGAN DERAJAT KEPARAHAN AKNE VULGARIS (STUDI PADA MAHASISWI FAKULTAS KEDOKTERAN UNIVERSITAS DIPONEGORO ANGKATAN 2012-2015) Hidayati, Noufry Zaliva; Riyanto, Puguh
DIPONEGORO MEDICAL JOURNAL (JURNAL KEDOKTERAN DIPONEGORO) Vol 6, No 2 (2017): JURNAL KEDOKTERAN DIPONEGORO
Publisher : DIPONEGORO MEDICAL JOURNAL (JURNAL KEDOKTERAN DIPONEGORO)

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (372.78 KB)

Abstract

Latar Belakang: Kelainan kulit yang sering terjadi pada remaja dan dewasa muda adalah akne vulgaris (AV). Penyebab AV adalah multifaktorial, salah satunya yaitu faktor stres. Stres merupakan suatu reaksi terhadap sebuah “perceived stimulus” (rangsangan yang dirasakan) dan reaksi ini berkemampuan untuk mengganggu keadaan homeostasis dari suatu makhluk hidup.Tujuan: Mengetahui hubungan tingkat stres dengan derajat keparahan AV dan perbedaan tingkat tingkat stres antara penderita AV dengan bukan penderita AV pada mahasiswi Fakultas Kedokteran.Metode: Penelitian ini menggunakan rancangan observasional cross-sectional pada bulan April-Mei 2016 di Fakultas Kedokteran Universitas Diponegoro dan Rumah Sakit Nasional Diponegoro Semarang. Sampel diambil secara simple random sampling menghasilkan 43 mahasiswi pada kelompok non AV dan 43 mahasiswi pada kelompok AV yang memenuhi kriteria inklusi tetapi tidak memenuhi kriteria eksklusi. Tingkat stres mahasiswi diukur dengan menggunakan skor BDI. Analisis data menggunakan uji Spearman sebagai uji korelasi dan uji Mann-Whitney sebagai uji beda.Hasil: Tingkat stres dengan derajat keparahan AV memiliki hubungan yang bermakna p=0,009 (p<0,05) dan tingkat stres antara kelompok AV dengan kelompok non AV memiliki perbedaan yang bermakna p=0,040 (p<0,05) dengan subjek penelitian mahasiswi Fakultas Kedokteran.Kesimpulan: Terdapat hubungan antara tingkat stres dengan derajat keparahan AV dan terdapat perbedaan tingkat tingkat stres antara penderita AV dengan bukan penderita AV pada mahasiswi Fakultas Kedokteran secara bermakna.
THE INFLUENCE OF CHEESE CONSUMPTION ON THE DEGREE OF ACNE VULGARIS IN STUDENTS OF MEDICINE FACULTY OF DIPONEGORO UNIVERSITY Koncara, Fatan Khalif; Wibowo, Dhega Anindita; Riyanto, Puguh; Wikanta, Edmond Rukmana
DIPONEGORO MEDICAL JOURNAL (JURNAL KEDOKTERAN DIPONEGORO) Vol 9, No 2 (2020): DIPONEGORO MEDICAL JOURNAL ( Jurnal Kedokteran Diponegoro )
Publisher : Faculty of Medicine, Diponegoro University, Semarang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (470.253 KB) | DOI: 10.14710/dmj.v9i2.27076

Abstract

Introduction : Acne vulgaris is a chronic inflammatory disease of pilosebaceous follicles with a polymorphic clinical picture consisting of various skin disorders in the form of blackheads, papules, pustules, nodules, and scar tissue. Four pathogenesis underlying the emergence of AV include polysebaseal follicle hyperproliferation, excess sebum production, inflammation, and the presence of Propionibacterium acnes. The cause of this multifactorial AV, one of which is a factor of consuming fatty foods, especially saturated fat, one of the foods is cheese. Cheese is one of the foods that we usually consume as processed foods that contain lots of saturated fat. Consuming fatty foods on an irregular basis can cause acne vulgaris. Objectives : To determine the relationship of fatty food consumption with the severity of acne vulgaris in Diponegoro University Kedokeran Faculty studentsMethods : This study uses a descriptive observational design with cross sectional design in which the researcher will describe how the incidence of acne vulgaris, the severity of acne vulgaris and the factors that influence acne vulgaris, especially regarding saturated fat consumption in excess cheese in Diponegoro University Medical School students. Samples were taken by purposive sampling to produce 40 students who met the inclusion and exclusion criteria. Assessment is assessed by filling out questionnaires suffering from acne vulgaris and assessing acne vulgaris in respondents. Analysis of the data used in the study is an analysis with the Chi Square test. Result : In conclusion, clustered pimples are a dominant factor in the assessment of acne (p<0,05). Conclusion: In this study it was found that there was no significant relationship between cheese consumption with the severity of acne vulgaris and pimples arising from acne is acne that occurred before the existence of this studyKeywords : acne vulgaris, fat, cheese
Association between Bubble Tea Consumption and Prevalence of Acne Vulgaris Subagio, Devina; Budiastuti, Asih; Riyanto, Puguh; Aryoko Widodo, Yulian Ludovicus
Cermin Dunia Kedokteran Vol 48, No 7 (2021): Infeksi - [Covid - 19]
Publisher : PT. Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (102.984 KB) | DOI: 10.55175/cdk.v48i7.1450

Abstract

Introduction: Acne vulgaris (AV) is one of the most common skin disorders among youth. A cross-sectional study was conducted to analyze the association between bubble tea consumption and the prevalence of acne vulgaris among medical students. Method: Subjects were obtained from consecutive sampling. There were 91 eligible subjects meeting inclusion criteria. Data was collected using questionnaires. Examinations were through observation of photographs of lesions. Chi-square analysis was conducted at a 95% confidence interval (p<0.05). Results: Data were collected from 91 medical students with mean age 19.62+0.98 year-old. The prevalence of acne was 58.2%; mostly in age 20 years (37.7%). There is a significant association between consumption of bubble tea and the prevalence of AV (p<0.001). Conclusion: Bubble tea consumption is associated with prevalence of acne vulgaris.Pendahuluan: Akne vulgaris merupakan salah satu penyakit kulit yang umum dialami pada dewasa muda. Metode: Penelitian observasional cross sectional untuk mengetahui asosiasi konsumsi bubble tea dengan kejadian akne vulgaris. Sampel diambil dengan metode consecutive sampling menghasilkan 91 mahasiswa yang memenuhi kriteria inklusi dan eksklusi. Pengambilan data primer dengan kuesioner. Pemeriksaan fisik observasi kulit responden dengan foto. Analisis data menggunakan uji Chi-Square dengan tingkat kemaknaan p<0,05. Hasil: Angka kejadian akne vulgaris adalah 58,2% dengan rata-rata usia 19.62+0.98; usia terbanyak penderita adalah 20 tahun (37,7%). Terdapat asosiasi bermakna antara konsumsi bubble tea dengan kejadian akne vulgaris (p<0,001). Simpulan: Penelitian ini menunjukkan hubungan bermakna antara konsumsi bubble tea dengan kejadian akne vulgaris.
Literature Review: The Role of Saffron (Crocus sativus L) in Cosmetic Dermatology Damayanti, Galih Sari; Riyanto, Puguh
Jurnal Kedokteran Diponegoro (Diponegoro Medical Journal) Vol 12, No 6 (2023): JURNAL KEDOKTERAN DIPONEGORO (DIPONEGORO MEDICAL JOURNAL)
Publisher : Faculty of Medicine, Universitas Diponegoro, Semarang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/dmj.v12i6.40711

Abstract

Background : Crocus sativus L known as saffron is widely discussed in Indonesia. Although saffron has been used since ancient times for medicinal and cosmetic purposes, scientific research on the mechanism of saffron in its role in promoting skin health is lacking. Objectives : This literature review is to determine the role of saffron in cosmetic dermatology. Methods : This article is a narrative research. The library sources that used was carried out through the database Google Scholar, PubMed, and Cochrane. The article search does not limit study design or study level. All articles were searched from 2012 to June 2023. The study inclusion criteria included: data available in English and Indonesian. Exclusion criteria were articles on the benefits of using saffron in the other field of dermatology and the use of saffron in combination with other topical active ingredients. Results : There were 16 articles which meet the criterias. It was found that saffron play role in the cosmetic dermatology such as in skin aging, melasma, as a photoprotection agents, skin moisturizer, prevention and treatment of skin cancer, as well as preparation of cosmetic products. Saffron has antioxidant, antiinflammatory, antipigmentation, antiwrinkle, anticarcinogenic and photoprotective activities. Conclusion : Crocus sativus L is a natural ingredient that has the potential to be further developed into medicinal forms, both oral and topical preparations because it is proven to have various pharmacological effects that play role in the cosmetic dermatology.
The Effect of Topical 0.1% Pomegranate Extract (Punica Granatum) on Trans Epidermal Water Loss (Tewl) and Skin Ph Levels in Patients with a History of Atopic Dermatitis Fernandes, Albert; Widayati, Retno Indar; Riyanto, Puguh
Jurnal Health Sains Vol. 5 No. 9 (2024): Journal Health Sains
Publisher : Syntax Corporation Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46799/jhs.v5i9.1353

Abstract

Repairing the skin barrier with moisturizers is one of the five main pillars of treating atopic dermatitis. Petrolatum is considered the gold standard, but its consistency is too thick and oily making it less comfortable to use. Moisturizers containing pomegranate extract (Punica granatum) can be an alternative choice that is more comfortable to use. The effectiveness of this pomegranate extract can be eval__uated using TEWL and pH examinations which are considered accurate indicators for changes in skin barrier conditions. Effectiveness of topical administration of 0.1% pomegranate extract in reducing TEWL and skin pH in sufferers with a history of AD.Single blind randomized clinical trial with two parallel group pre and post design. 34 sufferers with a history of AD were randomly divided into treatment groups (topical 0.1% pomegranate extract, 17 subjects) and control group (topical 100% petrolatum, 17 subjects). Moisturizer was applied twice daily to the volar area of ​​the forearm for 4 weeks. Both groups showed a significant decrease in TEWL after 4 weeks with a TEWL delta of -5.2±2.31g/m2/hour (p<0.001) in the pomegranate extract group and-7.0±7.95g/m2/hour(p=0.003) in the petrolatum group. There was no significant difference in TEWL reduction between the two study groups.The pomegranate extract group showed a significant decrease in pH after 4 weeks with a pH delta of -0.5±0.10(p<0.001), while the petrolatum group actually showed a slight increase with a pH delta of0.0±0.59 (p=0.6). The pomegranate extract group showed a significantly greater decrease in pH (p<0.001).Topical 0.1% pomegranate extract is as effective as 100% petrolatum in reducing TEWL, but more effective in lowering skin pH.
The Relationship Between Occupation and Incidence of Various Types of Melanocytic Nevi Riyanto, Puguh; Alexander, Lim
Jurnal Health Sains Vol. 6 No. 7 (2025): Journal Health Sains
Publisher : Syntax Corporation Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46799/jhs.v6i7.2671

Abstract

Melanocytic nevi (MN) are benign proliferations of melanocytes influenced by genetic and environmental factors, particularly ultraviolet (UV) radiation. Occupational exposure to sunlight may contribute to the development of different nevus types, but this relationship remains underexplored. This study aimed to examine the association between occupation and the incidence of various melanocytic nevi types. A descriptive observational study with a cross-sectional design was conducted among 20 participants in Semarang, Indonesia, from April to May 2025. Data were collected via validated questionnaires covering occupation (indoor/outdoor), protective measures (sunscreen, long-sleeved clothing), and nevus types (junctional, compound, intradermal). Statistical analysis was performed using SPSS. Results showed that 60% of participants had indoor occupations, while 40% worked outdoors. Among nevus types, 50% had compound nevi, 16% had junctional nevi, and 10% had intradermal nevi. A significant association was found between outdoor occupations and compound nevi (p = 0.010, RR = 3.50). No significant links were observed for junctional or intradermal nevi. Protective measures, such as sunscreen use, showed no significant impact, possibly due to low adherence (70% non-users). The findings suggest that occupational UV exposure may elevate the risk of compound nevi. Further research with larger samples and additional variables (e.g., sun exposure duration) is recommended to validate these results and to inform preventive strategies for at-risk populations.
The Effect of Local Anesthesia on Dermatological Actions on Patient Comfort Riyanto, Puguh; Priyanto, Olivia Jovina
Indonesian Journal of Global Health Research Vol 7 No 5 (2025): Indonesian Journal of Global Health Research
Publisher : GLOBAL HEALTH SCIENCE GROUP

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37287/ijghr.v7i5.7018

Abstract

Local anesthesia is commonly used in a variety of dermatological procedures to reduce pain and improve patient comfort. However, some side effects can occur, including burning sensations, nausea, vomiting, dizziness, blurred vision, and even impaired consciousness. This study aimed to evaluate the effect of local anesthesia on patient comfort during dermatological procedures. The study was conducted at an aesthetic clinic in Semarang from 7 to 9 February, involving 20 patients (2 men and 18 women). This study uses a quantitative descriptive study with a cross-sectional approach to assess patient comfort and side effects after local anesthesia in dermatologic procedures. Patients aged 18 and older who consent will be recruited consecutively. Researchers will using observation checklist and vital sign chart to collect demographic and clinical data, observe and record specific side effects such as feeling hot/sore, nausea, vomiting, dizziness, blurred vision, impaired consciousness, and fainting during and up to 30 minutes after the procedure, and monitor vital signs before and after the procedure. The results showed that 16 out of 20 patients reported no complaints after the procedure. Three patients experienced a burning sensation, while one patient experienced nausea and vomiting. None of the patients reported dizziness, blurred vision, loss of consciousness, or fainting. In conclusion, local anesthesia provides a high level of comfort for patients with minimal side effects. Therefore, it remains a safe and effective option for dermatological procedures, although monitoring individual responses remains important.
Influential Host Factors to the Incidence of HIV/AIDS in Key Populations in Pati District Murtono, Dwi; Riyanto, Puguh; Shaluhiyah, Zahroh
Kesmas Vol. 13, No. 1
Publisher : UI Scholars Hub

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Human Immunodeficiency Virus (HIV) dan Acquired Immune Deficiency Syndrome (AIDS) merupakan penyakit berbahaya di dunia yang salah satu metode penularannya adalah melalui hubungan seksual. Penelitian ini bertujuan menjelaskan faktor-faktor yang berpengaruh terhadap kejadian HIV/AIDS pada populasi kunci. Penelitian dilakukan dari bulan Maret sampai September 2016. Penelitian analitik observasional dengan rancangan kasus kontrol pada populasi kunci di Kabupaten Pati. Kasus sebanyak 53 pasien positif HIV/AIDS, sedangkan kontrol sebanyak 53 pasien negative HIV/AIDS.Pengambilan sampel menggunakan teknik consecutive sampling. Data diperoleh dari riwayat medis dan wawancara kuesioner. Penelitian ini menggunakan uji kai kuadrat pada analisis bivariat dan regresi logistik ganda pada analisis multivariat. Hasil penelitian menunjukkan bahwa faktor yang berpengaruh terhadap kejadian HIV/AIDS pada populasi kunci dalam penelitian ini adalah perilaku pemakaian kondom, riwayat menderita infeksi menular seksual, dan bentuk aktifitas seks kombinasi. Faktor yang tidak berpengaruh adalah perilaku multi pasangan seks, perilaku penggunaan aksesoris seks, perilaku penggunaan jarum tato, dan perilaku penggunaan narkoba suntik. Sebagai kesimpulan, faktor yang berpengaruh terhadap kejadian HIV/AIDS yaitu perilaku pemakaian kondom yang tidak konsisten, riwayat menderita IMS dan bentuk aktivitas seks kombinasi. Human Immunodeficiency Virus (HIV) and Acquired Immune Deficiency Syndrome (AIDS) are serious diseases in the world in which one of transmission methods is through sexual intercourse. This study aimed to explain the influential host factors to the incidence of HIV/AIDS in key populations. The study was conducted in March-September 2016. The study was observational analytic with case-control design in key populations in Pati District. Cases were 53 patients living with HIV/AIDS, while controls were 53 patients not living with HIV/AIDS. The sampling technique employed was consecutive sampling. Data were obtained from medical records and interview questionaire. This study applied chi-square test to analyze bivariate data, and multiple logistic regression to analyze multivariate data. Results indicated that the influential factors to the incidence of HIV/AIDS in key populations were inconsistent condom use behavior, records of suffering from sexually-transmitted infections (STIs), and forms of sexual activity. While, factors which were not influential to the incidence of HIV/AIDS were multiple sex partner behavior, sex accessory use behavior, tattoo needle use behavior, injecting drug use behavior. In conclusion, several influential factors to the incidence of HIV/AIDS in key populations are the inconsistent condom use behavior, records of suffering from STIs, and forms of sexual activity.
Comparison of the effectiveness of colloidal oatmeal 1% with petrolatum 100% to repair the skin bars in psoriasis vulgaris: A study of trans-epidermal water loss Riyanto, Puguh; Sugianto, Yosep Ferdinand Rahmat; Z, Mutia Dian Permatasari Mochtar
Science Midwifery Vol 13 No 4 (2025): October: Health Sciences and related fields
Publisher : Institute of Computer Science (IOCS)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35335/midwifery.v13i4.2118

Abstract

The purpose of this study was to compare the effectiveness of 1% colloidal oatmeal with 100% petrolatum in improving the skin barrier in patients with psoriasis vulgaris. This research method is a randomized, single-blind, pre and posttest design controlled trial involving patients with mild/moderate/severe psoriasis vulgaris at DR. Kariadi Hospital Semarang, Indonesia. The subjects of the study were divided into 2 groups, namely 1% colloidal oatmeal and 100% petrolatum. Evaluation was carried out by comparing the TEWL values between day 0 and day 28. The analysis was carried out using independent T-tests, Mann Whitney, and Wilcoxon. The results were significant if p<0.05 Results Topical administration of 1% colloidal oatmeal or 100% petrolatum could lower the TEWL value in each study group (p<0.001; p=0.006 respectively). ΔTEWL evaluation showed a significantly greater decrease in TEWL in the 1% colloidal oatmeal group (p=0.003). No complaints during use were reported in the 1% colloidal oatmeal group. Conclusion: Topical application of 1% colloidal oatmeal is more effective than 100% petrolatum as a moisturizer in improving the skin barrier in patients with psoriasis vulgaris without complaints.
Effectiveness of topical combination of finasterid and minoxidil in the management of male androgenetic alopesia (systematic review and meta-analysis: Hair density study) Riyanto, Puguh; Karami, Muhammad Zuldan; Malik, Diah Adriani
Science Midwifery Vol 13 No 4 (2025): October: Health Sciences and related fields
Publisher : Institute of Computer Science (IOCS)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35335/midwifery.v13i4.2119

Abstract

Androgenetic alopecia (AAG) is the most common hair loss problem in men, characterized by miniaturization of hair follicles due to systemic androgens and genetic factors. AAG treatment aims to prevent follicle miniaturization Treatment modalities for AAG include hair transplantation, platelet-rich plasma (PRP), microneedling, and stem cells. Each treatment modality has its benefits and risks. The combination of topical finasteride and topical minoxidil has been shown to improve outcomes in several studies. This study aimed to evaluate the efficacy of topical finasteride compared to topical minoxidil in improving hair density among male AAG patients. A systematic literature search method was conducted using MEDLINE, Embase, AMED, Cochrane Library, Clinicaltrials.gov, Web of Knowledge, Web of Science, and WHO ICTRP with the search terms "topical finasteride and minoxidil" 'AND' "male androgenetic alopecia" 'AND' "male pattern hair loss". The literature search was carried out in accordance with the PRISMA 2009 path. Three RCTs were included in the qualitative synthesis and included in the meta-analysis. The results showed that the overall SMD in hair density was 0.751±0.215 (95% CI: 0.331 – 1.162, p<0.001) in favor of topical finasteride and topical minoxidil combination treatment, suggesting that topical finasteride and topical minoxidil combination had much greater effectiveness than control treatments in improving hair density among male patients with AAG.