<![CDATA[Medical students experience substantial academic demands that increase their risk of developing academic-related stress (ARS). Caffeine is commonly consumed to improve alertness and academic performance, yet excessive intake may adversely affect sleep quality and psychological well-being. This study aimed to examine the associations between caffeine consumption, sleep quality, and academic-related stress among medical students. A cross-sectional analytic study was conducted among 139 medical students. Caffeine intake was assessed using a modified Caffeine Consumption Questionnaire (CCQ), sleep quality was evaluated using the Pittsburgh Sleep Quality Index (PSQI), and academic-related stress was measured using the Academic Related Stressor (ARS) domain of the Medical Student Stressor Questionnaire (MSSQ). Associations between variables were analyzed using the Chi-square test or Fisher's exact test, with statistical significance set at p < 0.05. Most participants were classified as low caffeine consumers (92.8%), with a mean daily caffeine intake of 36.65 ± 38.61 mg. Poor sleep quality was reported by 75.5% of participants, while 70.5% experienced severe to very severe academic-related stress. No significant association was found between caffeine consumption and ARS (p = 1.000). In contrast, poor sleep quality was significantly associated with higher odds of severe ARS (p = 0.031; OR = 2.399; 95% CI: 1.068–5.387). Sleep quality was significantly associated with academic-related stress, whereas caffeine consumption was not. Medical students with poor sleep quality had more than twice the likelihood of experiencing severe academic-related stress, highlighting the importance of promoting healthy sleep habits to support students' psychological well-being. Keywords : Academic-Related Stress, Caffeine Consumption, Medical Students, Sleep Quality, Psychological Well-Being]]>
