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CRYPTOSPORIDIOSIS: EPIDEMIOLOGI, PATOGENESIS, MANIFESTASI KLINIS, DIAGNOSIS, DAN PENATALAKSANAAN: TINJAUAN LITERATUR Nur Bebi Ulfah Irawati; Luluk Hermawati; Silvia Fitrina Nasution; Putri Damayanti; Yuda Nabella Prameswari; Hilizza Awalina Zulfa
JURNAL BIOSENSE Vol 9 No 2 (2026): Edisi April 2026
Publisher : Universitas PGRI Banyuwangi, Jalan Ikan Tongkol No 01, Telp (0333) 421593, 428592 Banyuwangi 68416

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36526/biosense.v9i2.7673

Abstract

Cryptosporidiosis is a parasitic infection caused by protozoa of the Cryptosporidium genus that infect humans and animals worldwide. The disease remains a significant public health concern, particularly in regions with limited access to clean water and adequate sanitation. This study aimed to review recent scientific evidence regarding the epidemiology, pathogenesis, clinical manifestations, diagnosis, and management of cryptosporidiosis. A literature review method was employed by analyzing scientific articles published between 2015 and 2025 retrieved from databases including PubMed, Scopus and Google Scholar. Relevant studies were selected based on predefined inclusion criteria and analyzed narratively. The review indicates that Cryptosporidium hominis and Cryptosporidium parvum are the most common species causing human infection and account for the majority of cases worldwide. Transmission primarily occurs through the fecal–oral route via contaminated water or food, as well as direct contact with infected hosts. Infection involves parasite attachment and invasion of intestinal epithelial cells, leading to mucosal damage, malabsorption, and diarrhea. Clinical manifestations vary depending on the host's immune status, ranging from mild self-limiting diarrhea in immunocompetent individuals to severe and chronic infection in immunocompromised patients. Diagnosis is commonly established through microscopic detection of oocysts, antigen-based assays, and molecular methods such as polymerase chain reaction (PCR). Current management mainly focuses on supportive therapy, while nitazoxanide remains the only antiparasitic drug approved by the FDA for the treatment of cryptosporidiosis. Therefore, improvements in sanitation, development of diagnostic methods, and effective prevention strategies are essential to reduce the global burden of cryptosporidiosis.
Association Between Caffeine Consumption, Sleep Quality, and Academic-Related Stress Among Medical Students Desasti Gustipraduga; Louisa Ivana Utami; Yuda Nabella Prameswari
International Journal of Medicine and Public Health Vol 3, No 2 (2026): October
Publisher : Universitas Sultan Ageng Tirtayasa

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62870/inomed.v3i2.42077

Abstract

Medical students experience substantial academic demands that increase their risk of developing academic-related stress (ARS). Caffeine is commonly consumed to improve alertness and academic performance, yet excessive intake may adversely affect sleep quality and psychological well-being. This study aimed to examine the associations between caffeine consumption, sleep quality, and academic-related stress among medical students. A cross-sectional analytic study was conducted among 139 medical students. Caffeine intake was assessed using a modified Caffeine Consumption Questionnaire (CCQ), sleep quality was evaluated using the Pittsburgh Sleep Quality Index (PSQI), and academic-related stress was measured using the Academic Related Stressor (ARS) domain of the Medical Student Stressor Questionnaire (MSSQ). Associations between variables were analyzed using the Chi-square test or Fisher's exact test, with statistical significance set at p < 0.05. Most participants were classified as low caffeine consumers (92.8%), with a mean daily caffeine intake of 36.65 ± 38.61 mg. Poor sleep quality was reported by 75.5% of participants, while 70.5% experienced severe to very severe academic-related stress. No significant association was found between caffeine consumption and ARS (p = 1.000). In contrast, poor sleep quality was significantly associated with higher odds of severe ARS (p = 0.031; OR = 2.399; 95% CI: 1.068–5.387). Sleep quality was significantly associated with academic-related stress, whereas caffeine consumption was not. Medical students with poor sleep quality had more than twice the likelihood of experiencing severe academic-related stress, highlighting the importance of promoting healthy sleep habits to support students' psychological well-being. Keywords : Academic-Related Stress, Caffeine Consumption, Medical Students, Sleep Quality, Psychological Well-Being
Environmental Risk Factors for Dry Eye Syndrome: A Literature Review on Air Conditioner Exposure, Gadget Use, and Reading Activity Yuda Nabella Prameswari; Rossa Amelia
International Journal of Medicine and Public Health Vol 2, No 1 (2025): April
Publisher : Universitas Sultan Ageng Tirtayasa

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62870/inomed.v2i1.34523

Abstract

Dry Eye Syndrome (DES) is a multifactorial disorder of the tear film and ocular surface characterized by discomfort, visual disturbances, and tear film instability that has the potential to damage the ocular surface. Environmental factors play a role in increasing the risk of DES, including exposure to air from air conditioners (AC), prolonged use of gadgets, and intense reading activities. This condition may result in reduced tear production or increased tear evaporation, contributing to the progression of dry eye symptoms. People regularly exposed to these factors are at higher risk of developing DES, especially when working in dry environments or focusing on screens for extended periods without sufficient rest. This review aims to examine the literature regarding the relationship between AC exposure, gadget use, and reading activities with the incidence of Dry Eye Syndrome and its implications for eye health. A better understanding of these risk factors is expected to serve as a basis for effective prevention and management of DES.