Article Per Year (5 Year)
p-Index From 2021 - 2026
0.23
P-Index
This Author published in this journals
All Journal Journal Pharmasci (Journal of Pharmacy and Science)
Rafifah Fadhilah
Sarjana Farmasi, Fakultas Farmasi, Universitas Airlangga
Biochemistry, Genetics & Molecular Biology Chemistry Health Professions Immunology & microbiology Medicine & Pharmacology

Published : 1 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 1 Documents
Search

 1 
Drug Utilization Study of Antiplatelet in Thrombotic Stroke Patients: Studi Penggunaan Antiplatelet Pada Pasien Stroke Trombotik samirah samirah; Rafifah Fadhilah; Rifdah Atikah Safitri; Abdulloh Machin; Suharjono; Nafa Rosyida Zanuba
Journal Pharmasci (Journal of Pharmacy and Science) Vol. 10 No. 2 (2025): Journal Pharmasci (Journal of Pharmacy and Science)
Publisher : Akademi Farmasi Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53342/pharmasci.v10i2.483

Abstract

Stroke is the mayor cause of death and disability in Indonesia, with the thrombotic stroke being is the leading cause. Thrombotic stroke occurs due to the formation of a thrombus in the brain’s blood vessels, necessitating antiplatelet therapy to prevent recurrent stroke and other cardiovascular diseases. This study aim to identify pattern of antiplatelet therapy, adverse drug reaction, as well as drug-drug interaction related to antiplatelet. A total of 50 adult thrombotic stroke inpatient was observed in this observational-retrospective study. The most frequent antiplatelet used were acetosal (40%), clopidogrel (28%), followed by acetosal clopidogrel combination (28%), and acetosal-cilostazol combination (4%). In this study, 60% of ADR was identified, of which 16% was nausea and vomiting and 44% was dyspepsia. Five potential drug-drug interaction were identified, including acetosal-ACE inhibitor (6%), acetosal-NSAID (24%), Clopidogel-PPI (10%), and Clopidogrel-Statin (48%).
Co-Authors Abdulloh Machin Nafa Rosyida Zanuba Rifdah Atikah Safitri samirah samirah Suharjono