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All Journal Journal Pharmasci (Journal of Pharmacy and Science)
Suharjono
Airlangga University
Biochemistry, Genetics & Molecular Biology Chemistry Health Professions Immunology & microbiology Medicine & Pharmacology

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Drug Utilization Study of Antiplatelet in Thrombotic Stroke Patients: Studi Penggunaan Antiplatelet Pada Pasien Stroke Trombotik samirah samirah; Rafifah Fadhilah; Rifdah Atikah Safitri; Abdulloh Machin; Suharjono; Nafa Rosyida Zanuba
Journal Pharmasci (Journal of Pharmacy and Science) Vol. 10 No. 2 (2025): Journal Pharmasci (Journal of Pharmacy and Science)
Publisher : Akademi Farmasi Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53342/pharmasci.v10i2.483

Abstract

Stroke is the mayor cause of death and disability in Indonesia, with the thrombotic stroke being is the leading cause. Thrombotic stroke occurs due to the formation of a thrombus in the brain’s blood vessels, necessitating antiplatelet therapy to prevent recurrent stroke and other cardiovascular diseases. This study aim to identify pattern of antiplatelet therapy, adverse drug reaction, as well as drug-drug interaction related to antiplatelet. A total of 50 adult thrombotic stroke inpatient was observed in this observational-retrospective study. The most frequent antiplatelet used were acetosal (40%), clopidogrel (28%), followed by acetosal clopidogrel combination (28%), and acetosal-cilostazol combination (4%). In this study, 60% of ADR was identified, of which 16% was nausea and vomiting and 44% was dyspepsia. Five potential drug-drug interaction were identified, including acetosal-ACE inhibitor (6%), acetosal-NSAID (24%), Clopidogel-PPI (10%), and Clopidogrel-Statin (48%).
The Effect of Animated Video on Diabetic Patients' Knowledge Regarding Medication Use, Side Effects, and Their Management: Peningkatan Pengetahuan Pasien Diabetes Mellitus Terkait Penggunaan Obat, Efek Samping, dan Pengatasannya melalui Video Animasi Wenny Putri Nilamsari; Budi Suprapti; Dewi Wara Shinta; Mareta Rindang Andarsari; Bambang Subakti Zulkarnain; Suharjono; Khusnul Fitri Hamidah; Meuthia Handayani; Hikma Urwatil Wusqo; Wanda Maharani Putri; Desi Jannati
Journal Pharmasci (Journal of Pharmacy and Science) Vol. 10 No. 2 (2025): Journal Pharmasci (Journal of Pharmacy and Science)
Publisher : Akademi Farmasi Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53342/pharmasci.v10i2.535

Abstract

The prevalence of Type 2 Diabetes Mellitus cases in Indonesia shows a rising trend. Based on Riskesdas 2018, the prevalence of DM according to the PERKENI consensus in the population >15 years old increases every year from 6.9% in 2011, 8.5% in 2015 and to 10.9% in 2018. As many as 75% of patients receive therapy OAD, 5% insulin injection, 11% OAD and insulin, and 9% untreated. According to several study reports, patient compliance in using diabetes medication is around 50%. One of the causes of patient non-compliance is the side effects of insulin therapy or OAD. This research is aimed at analyzing the provision of education with animated videos on type 2 DM patients' knowledge regarding medication use, side effects and their management. The results of the study showed that from a total sample of 40 patients, animated videos could increase patient knowledge significantly with the average value of patient knowledge before education being 38.4 ± 20.1 and after education being 85.9 ± 15.8 (p<0.05). Meanwhile, the percentage of patients who had good knowledge increased from 0% to 67.5% (p<0.05). Thus, it can be concluded that there is an increase in patient knowledge regarding the use of diabetes medications, side effects, and its management as well as related strategies for increasing compliance after education using animated video media.
Co-Authors Abdulloh Machin Bambang Subakti Zulkarnain Budi Suprapti Desi Jannati Dewi Wara Shinta Hikma Urwatil Wusqo Khusnul Fitri Hamidah Mareta Rindang Andarsari Meuthia Handayani Nafa Rosyida Zanuba Rafifah Fadhilah Rifdah Atikah Safitri samirah samirah Wanda Maharani Putri Wenny Putri Nilamsari