<![CDATA[Cancer patients receiving chemotherapy frequently experience multiple physical and psychological challenges that may interfere with daily functioning and overall well-being. Fatigue, anxiety, and disturbed sleep are common treatment-related problems that can occur simultaneously and potentially contribute to a decline in quality of life. Understanding the relationship among these factors is important for developing comprehensive nursing interventions for patients undergoing chemotherapy. Objective this study aimed to examine the relationships between fatigue, anxiety, sleep quality, and quality of life among cancer patients undergoing chemotherapy. Methods a quantitative correlational study was conducted among cancer patients receiving chemotherapy. Participants were recruited according to predetermined inclusion and exclusion criteria. Data were collected using standardized instruments to assess fatigue, anxiety, sleep quality, and quality of life. Descriptive analysis was performed to characterize the study variables, while bivariate analysis was used to determine the relationships between fatigue, anxiety, sleep quality, and quality of life. Statistical significance was established at a conventional significance level. Results the findings indicated that fatigue, anxiety, and poor sleep quality were commonly experienced by patients undergoing chemotherapy. Higher levels of fatigue were associated with poorer quality of life. Similarly, greater anxiety was related to reduced quality of life, while inadequate sleep quality was also associated with less favorable quality-of-life outcomes. These findings suggest that physical symptoms, psychological distress, and sleep disturbances may interact and collectively influence patients’ perceptions of their well-being during chemotherapy treatment. Conclusion fatigue, anxiety, and sleep quality are important factors associated with quality of life in cancer patients receiving chemotherapy. Nursing care should therefore incorporate systematic assessment and appropriate interventions addressing physical exhaustion, emotional distress, and sleep disturbances to support patients’ quality of life throughout the chemotherapy process.]]>
