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NILAI RUJUKAN UNTUK EVALUASI FUNGSI HATI DAN GINJAL PADA TIKUS (Rattus norvegicus Berkenhout, 1769) GALUR WISTAR Fitria, Laksmindra; Lukitowati, Fajar; Kristiawati, Dian
Jurnal Pendidikan Matematika dan IPA Vol 10, No 2 (2019): Juli 2019
Publisher : Universitas Tanjungpura

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (1037.481 KB) | DOI: 10.26418/jpmipa.v10i2.34144

Abstract

Evaluation of liver and renal functions are routine tests performed in preclinical studies. Liver plays a role in detoxification and secretion of various substances to regulate a wide range of metabolic functions. Kidneys serves as the main excretory and osmoregulatory organs. Thus, assessment of liver and renal functions are important in identifying the presence of damages and diseases as well as monitoring body responses towards treatments or therapy. Therefore, normal values should be established for valid reference. Until now, many researchers still use references from various publications, including foreign countries with different environmental factors and method of animals care. This study was aimed to provide reference values for liver and renal functions in male and female Wistar rats. Animals were sourced from LPPT-UGM. Age 4-, 6-, and 8-week-old represent juvenile, preadult, and adult. Blood samples were collected from orbital sinus of anesthetized animals. Sera were tested for ALT, AST, BUN, and creatinine based on spectrophotometry. Results demonstrated that values of most parameters varied, depend on sex and age. According to this finding, it can be concluded that reference values cannot be generalized but must be determined by sex and age in local population.
Development of antibacterial dual active food packaging based on super water absorbent and ethanol emitter: Pengembangan kemasan pangan aktif ganda antibakteri berbasis super water absorbent dan etanol emitter Nilatany, Asti; Kusumaningrum, Harsi Dewantari; Suyatma, Nugraha Edhi; Mulyanto, Rizky Nuur Berlianni; Yunus, Ade Lestari; Pratama, Indra Mustika; Sasmita, Hadian Iman; Lukitowati, Fajar; Benita, Ashri Mukti; Syahputra, Akhmad Rasyid; Oktaviani, Oktaviani; Nuryanthi, Nunung
Jurnal Teknologi & Industri Hasil Pertanian Vol. 30 No. 2 (2025): Jurnal Teknologi & Industri Hasil Pertanian
Publisher : Teknologi Hasil Pertanian Fakultas Pertanian Universitas Lampung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23960/jtihp.v30i2.133-143

Abstract

One way to extend shelf life and maintain the quality of fresh chicken meat is to implement an active packaging system. This research aimed to develop active packaging in the form of pads used in chicken meat with dual functions: Super Water Absorbent (SWA) as an adsorbent system and Ethanol Emitter (EE) as an antibacterial release system. The packaging in this study was first carried out by making SWA/EE with a ratio of 0, 4, and 2 (b/v). Furthermore, SWA/EE granules were inserted into non-woven PP bags to form an adsorbent active packaging pad. The experimental design used was a Randomized Group Design (RGD) with 2 factors, namely SWA/EE pad ratio 0, 4, and 2 (b/v) with non-pad as control and storage time (0, 1, 3, 5, and 7 days). Each treatment was repeated 3 times. The results showed that the SWA/EE ratio 4 (w/v) had better ethanol release and water absorption rate compared to other treatments. SWA/EE treatment with SWA/EE ratio of 4 (b/v) showed a significant difference on the anti-bacterial activity of S. aureus (34.58 mm) and total bacterial growth on storage days 3, 5, and 7, with the lowest value on day 3 (1.52 log CFU/g). SWA/EE treatment did not significantly different on the antibacterial activity of E. coli and total bacterial growth at day 1 storage. Packaging with an SWA-EE ratio of 4 (w/v) has the potential to be a double active packaging that can be used on fresh chicken meat.