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Puspa Dwi Pratiwi
Departement of Pharmacy, University of Jambi, Indonesia
Health Professions Medicine & Pharmacology Nursing Public Health

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Irritation, hedonic, and hair growth effectiveness tests of black cumin (Nigella sativa L.) oil-based shampoo nanoemulsion seprina; Uce Lestari; M. Rifqi Efendi; Puspa Dwi Pratiwi
Riset Informasi Kesehatan Vol 15 No 3 (2026): Riset Informasi Kesehatan
Publisher : Sekolah Tinggi Ilmu Kesehatan Harapan Ibu Jambi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30644/zqmgcp50

Abstract

Background: Hair loss is a common dermatological problem in Indonesia that affects the quality of life of those affected. Black cumin oil (Nigella sativa L.) contains thymoquinone, essential fatty acids, and antioxidants that have the potential to inhibit hair loss while simultaneously stimulating hair growth. A nanoemulsion formulation was selected to enhance the penetration of active ingredients into the scalp more optimally. Method: This experimental study involved 20 volunteer panelists, with assessments including a skin irritation test, hedonic test (aroma, texture, freshness, and comfort), and hair growth effectiveness test using a digital microscope on days 1, 3, 5, 7, 14, and 21. Results: The irritation test yielded an average score of 0.1, with more than 95% of panelists showing no signs of irritation. The hedonic test demonstrated positive responses from all panelists across all evaluated parameters. Hair growth was first detected on day 5 and continued to develop evenly through day 21. Conclusion: The black cumin oil nanoemulsion shampoo was proven to be safe, well-accepted organoleptically, and effective in stimulating hair growth, making it a promising natural-based hair care alternative.
Co-Authors M. Rifqi Efendi seprina Uce Lestari