Exclusive breastfeeding affects the health of infants; the fewer infants who are exclusively breastfed, the poorer the health of infants and toddlers will be (Indonesian Ministry of Health, 2018). Based on data from the Nusa Indah Community Health Center in Bengkulu City, the rate of exclusive breastfeeding has increased for three consecutive years. In 2021, the exclusive breastfeeding rate stood at 64.25%; in 2022, it was 49.2%; and in 2023, it stood at 36.45%. This study aims to determine the relationship between mothers’ knowledge and attitudes toward exclusive breastfeeding and the development of infants aged 7–12 months in the service area of the Nusa Indah Community Health Center in Bengkulu City in 2025. The research method used was a descriptive quantitative correlational study with a cross-sectional approach. The sampling technique employed total sampling, with a sample size of 48 respondents in the service area of the Nusa Indah Community Health Center in Bengkulu City. The results of the univariate analysis showed that the majority of respondents (56.3%) had insufficient knowledge and an unfavorable attitude, while the majority of respondents (70.8%) had normal development, and nearly a third of the respondents (35.4%) were in the normal range. The results of the bivariate analysis revealed a relationship between mothers’ knowledge of exclusive breastfeeding and the development of 7-month-old infants –12 months in the service area of the Nusa Indah Community Health Center, Bengkulu City, in 2025 (p = 0.000), and a relationship between mothers’ attitudes toward exclusive breastfeeding and the development of infants aged 7–12 months in the service area of the Nusa Indah Community Health Center, Bengkulu City, in 2025 (p = 0.000). It is hoped that this study can serve as a guide for policy-making regarding maternal and child health (MCH) programs, particularly concerning the importance of exclusive breastfeeding.