Fractures can impair physical function, mobility, comfort, independence, and sleep, while pain and hospitalization-related factors may influence patients’ adaptation during recovery. This study aimed to explore sleep quality and pain experiences among hospitalized fracture patients and analyze their adaptive responses using Roy’s Adaptation Model (RAM). A qualitative descriptive design was conducted with 10 fracture patients hospitalized in the RSUD Dr. Soehadi Prijonegoro Sragen. Participants were selected through purposive sampling based on predetermined criteria, and data were collected using in-depth semi-structured interviews and analyzed thematically, followed by mapping the findings onto RAM’s four adaptive modes. Seven interconnected themes emerged: disrupted sleep during hospitalization; pain as a barrier to sleep and mobility; psychological responses to illness and uncertainty; reduced functional independence; family as a source of safety and support; nursing care and the need for comfort-oriented support; and hope for recovery and restoration of normal life. Participants adapted through repositioning, relaxation, limiting painful movements, seeking assistance, communicating with family, and utilizing nursing support. These experiences reflected adaptation across the physiological-physical, self-concept/group identity, role function, and interdependence modes. The findings indicate that pain and sleep disturbances are interconnected and influenced by physical, environmental, psychological, functional, and interpersonal factors. An adaptation-oriented nursing approach integrating pain management, sleep promotion, comfort, functional support, psychological reassurance, and family involvement is important to facilitate patients’ recovery and restoration of daily activities.