Djou, Rahmatia
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Oral Manifestation Related to Drug Abuse : A Systematic Review: Manifetasi oral terkait penggunaan obat-obatan terlarang : Sebuah tinjauan sistematis Djou, Rahmatia; Dewi, Tenny Setiani
Dentika: Dental Journal Vol. 22 No. 2 (2019): Dentika Dental Journal
Publisher : TALENTA

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (577.981 KB) | DOI: 10.32734/dentika.v22i2.759

Abstract

Drug abuse influences the pathological of oral diseases. There are scarce evidence-based data on the oral manifestations related to drug abuse. This systematic review aim to assess the oral manifestations related to drug abuse. Electronic databases were searched using keywords include oral manifestations and drug abuse. Observational studies published until September 2018 with the outcome of oral manifestations related to drug abuse were included. Data were extracted as percentage include drug type, route of administration, and oral manifestations. Study quality was assessed using the quartile score of Scopus index. The systematic review of 17 studies revealed that methamphetamine (53%), heroin (41%), cannabis (35%), and cocaine (35%) were the most frequent abused drugs from 10139 samples. The routes of administration include smoking (58%),inhalation (35%), injection (35%), and oral route (17%), with duration of use ranged from one year to forty years. The most significant of oral manifestations reported were periodontal diseases (76%), dental caries (76%), and xerostomia (41%). Adverse drug reaction in oral cavity may cause, directly or indirectly, immunosuppression, susceptibility to infections, and oral pathologies due to chemical composition and mechanism of action specifically to drug type related with duration of use and route of administration.
Pattern of oral lesions in multidrugs resistant tuberculosis patient and the management: a case report Djou, Rahmatia; Setiadhi, Riani
Journal of Case Reports in Dental Medicine Vol 2, No 2 (2020)
Publisher : Hasanuddin University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20956/jcrdm.v2i2.106

Abstract

Objectives: to describe the pattern of oral lesions in MDR TB patient and the management. Methods: A 42-year-old man with history of TB since 8 months before and MDR TB since 1 month. The patient complained of sore tongue since 2 weeks before, accompanied with white plaque on the tongue which could be scrapped off leaving erythema areas. Intraoral examination showed multiple ulcers at lateral and dorsum of the tongue, white plaques on the tongue, buccal mucosa, labial mucosa, and palate. Swab examination from the tongue showed a positive result for Gram-positive Bacillus Bacteria. Tuberculosis ulcers and oral candidiasis were the diagnosis, so that the given treatment were nystatin oral suspension and 0.2% chlorhexidine gluconate mouthwash. Result: Ulcer and white plaques improved within 3 weeks. Conclusion: The clinical manifestation of oral tuberculosis lesions usually non-specific and sometimes similar with other lesions, making it difficult to be diagnosed