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Kondisi kesehatan gigi dan mulut siswa SDK Yahya tahun ajaran 2012-2013The oral health conditions of the Yahya Christian Elementary School students batch 2012-2013 Wihardja, Rosiliwati; Setiadhi, Riani
Jurnal Kedokteran Gigi Universitas Padjadjaran Vol 30, No 1 (2018): April
Publisher : Fakultas Kedokteran Gigi Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (321.335 KB) | DOI: 10.24198/jkg.v30i1.16247

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Pendahuluan: Rongga mulut terdiri dari jaringan lunak maupun jaringan keras, merupakan anggota tubuh yang penting untuk dijaga seperti anggota tubuh lainnya. Meningkatkan pengetahuan dan sikap yang diberikan sejak usia sekolah dapat mengatasi timbulnya masalah kesehatan rongga mulut. Metode: Penelitian ini bersifat deskriptif dari data/catatan kesehatan jaringan lunak dan keras mulut siswa SDK Yahya tahun ajaran 2012–2013. Hasil: Sebagian besar siswa mempunyai gingiva, mukosa bukal, mukosa labial, frenulum, lidah dan saliva yang normal serta seluruh siswa mempunyai palatum durum dan molle yang normal. Persentasi gigi berlubang, tambalan dan hilang pada siswa dinilai kecil. Keadaan ini menunjukkan bahwa umumnya siswa mempunyai integritas jaringan lunak mulut yang baik serta jaringan keras yang baik. Simpulan: Kondisi kesehatan gigi dan mulut siswa SDK Yahya tahun ajaran 2012 – 2013 adalah baik. ABSTRACTIntroduction: The oral cavity consists of both hard and soft tissues that are vital to be maintain like the other part of the body. Improving knowledge and behavior which was given since school age could overcome the incidence of oral health problems. Methods: This was a descriptive study using health records on both hard and soft tissues of students from Yahya elementary school of 2012/2013 academic year. Results: This study revealed that most students had normal gingiva, buccal mucosa, labial mucosa, frenulum, tongue and saliva and all students had normal palatum durum and molle. The percentage of cavities, fillings and tooth-loss on the students was considered small. Such findings demonstrated that in general, the students had decent integrity of both soft and hard oral tissues. Conclusion: It is concluded that the good conditions of both soft and hard oral tissues among Yahya elementary students of 2012/2013 academic year can be ascribed to the success of oral health education on the students.Keywords: Oral hard tissue, oral physiology, oral soft tissue.
Gambaran klinis smoker’s melanosis pada perokok kretek ditinjau dari lama merokokThe clinical features of smokers melanosis in kretek smokers by the smoking period Vieta, Cynthia; Setiadhi, Riani; Zubaedah, Cucu
Jurnal Kedokteran Gigi Universitas Padjadjaran Vol 29, No 1 (2017): April
Publisher : Fakultas Kedokteran Gigi Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (299.938 KB) | DOI: 10.24198/jkg.v30i3.18532

Abstract

Pendahuluan: Kebiasaan merokok sudah melekat di masyarakat Indonesia. Terdapat beberapa jenis rokok, diantaranya adalah rokok kretek. Rokok mengandung berbagai zat yang berbahaya bagi tubuh. Salah satu efek buruk rokok adalah smoker’s melanosis yang merupakan kelainan pigmentasi di rongga mulut. Tujuan penelitian adalah untuk mengetahui gambaran klinis smoker’s melanosis pada perokok kretek ditinjau dari lama merokok. Metode: Penelitian ini dilakukan secara deskriptif dengan metode survei. Sampel yang diambil sebanyak 80 orang dengan menggunakan teknik stratified sampling. Hasil: Sebanyak 46,3% responden yang mengalami pigmentasi meluas ternyata memiliki kebiasaan merokok kretek lebih dari 20 tahun. Simpulan: Frekuensi pigmentasi meluas paling banyak terdapat pada kelompok perokok yang sudah merokok selama lebih dari 20 tahun. ABSTRACTIntroduction: Smoking habits are inherent in Indonesian society. There are several types of cigarettes, including kretek cigarettes. Cigarettes contain various substances that are harmful to the body. One of the bad effects of cigarettes is smokers melanosis which is a pigmentation disorder in the oral cavity. The purpose of the study was to determine the clinical picture of smokers melanosis in kretek smokers in terms of smoking duration. Methods: This research was carried out descriptively by survey method. Samples taken were 80 people using stratified sampling technique. Results: A total of 46.3% of respondents who experienced widespread pigmentation turned out to have a smoking habit of kretek more than 20 years. Conclusion: The frequency of widespread pigmentation is most common among smokers who have smoked for more than 20 years.Keywords: Kretek cigarettes, smokers melanosis, smoking period.
Hubungan Antara Pigmentasi Melanin pada Gingiva Anak-anak dengan Riwayat Orang Tua Perokok di RSGM FKG Unpad (II) Riani Setiadhi -; Willyanti Soewondo -
Bionatura Vol 13, No 1 (2011): Bionatura Maret 2011
Publisher : Direktorat Sumber Daya Akademik dan Perpustakaan

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (283.244 KB)

Abstract

Merokok adalah kebiasaan yang sering dijumpai setiap hari dan sudah menjadi masalah yang kompleks secara sosial, karena dapat merupakan salah satu penyebab kematian . Bahaya dari secondhand smoke atau perokok pasif yaitu asap rokok yang terhirup oleh orang-orang bukan perokok karena berada disekitar perokok, akan mengalami gangguan kesehatan lebih menyeluruh dari yang diperkirakan sebelumnya. Perokok aktif menunjukkan adanya pigmentasi pada mukosa mulut terutama pada permukaan labial gingiva gigi anterior, berwarna coklat muda, coklat, coklat tua sampai hitam. Tujuan penelitian ini adalah untuk mencari hubungan antara pigmentasi melanin pada gingiva anak dengan riwayat orang tua perokok. Jenis penelitian adalah deskriptif analitik dengan metode survei. Pemeriksaan dilakukan pada pasien anak bukan perokok berusia 0 - 14 tahun dengan orangtua perokok, kriteria penilaian berdasarkan indeks modifikasi melanin. Jumlah subjek adalah 91 anak dan analisa statistik yang digunakan adalah analisis Chi-square, uji korelasi eta dan uji F. Hasil penelitian menunjukkan bahwa terdapat hubungan signifikan antara kebiasaan merokok orang tua dengan adanya pigmentasi pada permukaan labial gingiva gigi anterior anak di RSGM FKG Unpad. Kata kunci : merokok, pigmentasi melanin
Toxic epidermal necrolysis dipicu oleh parasetamol dan kloramfenikol Hamdatun Rakhmania; Riani Setiadhi
MKGK (Majalah Kedokteran Gigi Klinik) (Clinical Dental Journal) UGM Vol 4, No 3 (2018)
Publisher : Fakultas Kedokteran Gigi, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/mkgk.65718

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Toxic epidermal necrolysis (TEN) adalah peradangan sistemik akut yang melibatkan kulit, membran mukosa, epitel pernafasan dan pencernaan. Dalam banyak kasus, obat-obatan merupakan penyebab utama TEN akan tetapi dapat juga disebabkan oleh infeksi dan faktor resiko lain. Membran mukosa (rongga mulut, konjungtiva dan anogenital) adalah bagian tubuh yang paling awal terlibat pada TEN. Tujuan dari studi kasus membahas mengenai Toxic epidermal necrolysis yang dipicu oleh parasetamol dan kloramfenikol serta manajemen terapinya. Seorang wanita berumur 34 tahun mengeluh, empat hari sebelum rawat inap merasa pusing dan nyeri menelan, ia minum obat parasetamol dan kloramfenikol untuk mengobatinya. Tiga hari kemudian timbul luka pada kelopak mata dan bibir sehingga terasa nyeri saat membuka mata dan mulut. Pada bibir ditemukan krusta serosanguis yang mudah berdarah dan epidermolysis 32% pada kulit serta di mukosa oral terdapat lesi erosif, pseudomembran, eritem dan edema. Berdasarkan gambaran klinis, ditegakkan diagnosis TEN yang dipicu oleh parasetamol dan kloramfenikol. Terapi yang diberikan pada kunjungan pertama adalah kompres bibir dengan NaCl 0,9 %, 3 hari kemudian ditambahkan obat kumur chlorhexidine gluconate 0,1%. Mulai hari ke-7 ditambahkan terapi deksametason racikan dalam bentuk salep dan obat kumur. Setelah 10 hari menjalani perawatan, perih serta luka pada bibir dan rongga mulut sudah mengalami perbaikan, nyeri menelan pun berkurang. Kesimpulan: Tanda awal TEN adalah ruam dan lepuh pada mulut sehingga dokter gigi memiliki peranan penting dalam deteksi dini kelainan ini. Dokter gigi harus tanggap dan segera merujuk ke dokter spesialis kulit jika ditemukan tanda awal TEN, sehingga dapat segera diterapi sejak dini.
TERAPI IMUNOSUPRESAN PADA PASIEN ANEMIA APLASTIK DENGAN PERDARAHAN GUSI: MENYEMBUHKAN ATAU MEMPERPARAH? Revi Nelonda; Eliza Kristina Munthe; Riani Setiadhi
ODONTO : Dental Journal Vol 6: Special Issue 1. April 2019
Publisher : Faculty of Dentistry, Universitas Islam Sultan Agung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30659/odj.6.1.23-29

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Background: Aplastic anemia (AA) is a hematologic disorder characterized by hypoplastic bone marrow and peripheral pancytopenia. The main symptoms are fatigue and bleeding. In the oral cavity, gingival bleeding is the common complaint.Case Management: A 18-year-old female patient referred from internal medicine department due to swelling of palate since 2 days before that interrupted eating activity. She routinely consumes Sandimun®100 mg tablets. A 2 x 1 cm black blood clot in anterior hard palate and ulcerative lesion at dorsal tongue regio 45 surrounded by necrotic area were found on intra oral examination. Patient was diagnosed with necrotizing ulcer-related neutropenia accompanied by AA-associated hemorrhagic bullae in the hard palate. Patient treated with mouthwash containing 0.1% hyaluronicacid and 1% feracrylum.Discussion: Immunosuppressant is the AA gold standard therapy. Cyclosporine (CsA) as imunosupressant is common drug to prevent T cells from attacking stem cells in bone marrow. The side effects of CsA is gingival hiperplasia.Conclusions: Gingival bleeding and gingival hiperplasia due to thrombocytopenia and the use of cyclosporine are vicious circles that need to be aware. With comprehensive management, good oral conditions will be obtained, therefore the quality of life can increase.
VIRUS AS A CAUSE OF SALIVARY GLAND DISEASES Etis Duhita Rahayuningtyas; Riani Setiadhi
ODONTO : Dental Journal Vol 6: Special Issue 1. April 2019
Publisher : Faculty of Dentistry, Universitas Islam Sultan Agung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30659/odj.6.1.37-42

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Background: Enlargement in the extraoral region with the absence of abnormal dental and periodontal structures are sometimes seen in dental practice, sometimes followed by xerostomia. Enlargement of the acute nonsuppurative salivary glands has been associated with several types of viruses. The purpose of this paper is to review salivary gland diseases associated with non-HIV and HIV viral infections.Discussion: Non-HIV viruses which were detected in the salivary glands including Paramyxovirus, cytomegalovirus (CMV), Hepatitis C virus (HCV), human papilloma viruses (HPV), Epstein-Barr virus (EBV), human herpes simplex virus (HHSV-8), and coxsackie virus. HIV-associated salivary gland disease typically presents with xerostomia and/or intraglandular lymph nodes, and diffuse infiltrative lymphocytosis syndrome (DILS). The most common viral infection conditions in salivary gland disorders are mumps and HIV. Enlargement and inflammation of the glandular structures will affects the control of salivary secretion by nerves. Parasympathetic nerves block conducted signals to the salivary glands, so the salivary flow isdecreased.Conclusion: There is association between viral infection and diseases of thesalivary gland. By knowing sequelae viruses on the salivary gland, dentists are expected to understand the clinical condition and therapeutic that should be given to the patients.
MANAGEMENT OF BURNING MOUTH SYNDROME: A LITERATURE REVIEW I Nyoman Gede Juwita Putra; Riani Setiadhi
ODONTO : Dental Journal Vol 6: Special Issue 1. April 2019
Publisher : Faculty of Dentistry, Universitas Islam Sultan Agung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30659/odj.6.1.43-50

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Background: Burning mouth syndrome (BMS) is a chronic idiopathic oral dysaesthesia that presents as a burning sensation in the oral cavity usually without any specific oral lesions or laboratory findings. Burning sensations may appear on the buccal mucosa, hard and soft palate, tongue and lips. BMS appears to be more prevalent in postmenopausal women. The term menopause is often used for a condition in which the permanent cessation of the primary function of the ovaries in humans that occurs especially in middle-aged women. Available evidence suggested that BMS is a multifactorial disorder with physiological basis. Pathophysiology of BMS remains unclear. The etiopathogenesis in most patients who complain of burning sensations have interactions with several factors such as local, systemic, and/ or psychogenic factors. The aim of this literature review was to assess and evaluate the management of BMS comprehensively.Discussion: The therapy of BMS including hormone replacement therapy,systemically therapy, such as antidepressants, clonazepam and topical medication (clonidine and capsaicin) and reassurance as the stress management.Conclusion: Proper management of the BMS involves the combination of pharmacologic treatment and psychotherapy, as well as reassurance is an important thing
THYMIDINE KINASE AS A CAUSATIVE FACTOR FOR TYPE 1 HERPES SIMPLEX VIRUS RESISTANCE AGAINST ACYCLOVIR Yannie Febby Martina Lefaan; Riani Setiadhi
Dentino : Jurnal Kedokteran Gigi Vol 5, No 2 (2020)
Publisher : FKG Unlam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/dentino.v5i2.8954

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ABSTRACTBackground: Herpes Simplex Virus (HSV) infection demonstrates a high prevalence in the world. Acyclovir, one of guanine synthetic analogues, is commonly used to treat infections caused by HSV. HSV resistance against acyclovir may occur, especially in immunocompromised and immunocompetent patients, as the consequence of viral mutations. Thymidine kinase (TK) is an HSV tegument protein which plays an important role in HSV-1 resistance against acyclovir. Purpose: The purpose of this article is to review the mechanisms of TK mutation that cause HSV-1 resistance against acyclovir. Review: Acyclovir involves three stages of viral thymidine kinase phosphorylation to form acyclovir triphosphate. It prevents HSV replication by acting as a competitive inhibitor of viral DNA polymerase and a chain terminator in viral DNA synthesis. Resistance is associated with viral TK mutation that is encoded by UL23 gene. Long-term use of acyclovir may promote thymidine kinase mutation in immunocompromised and immunocompetent patients via three mechanisms, namely absolute insufficiency in TK activity (TK-negative), depletion in TK synthesis, and inability in TK phosphorylation which consequently hinders the phosphorylation of acyclovir. Herpes TK gene contains a series of cytosine and guanosine, that are important for the function and the  mutation of HSV by producing incomplete or fewer enzymes as the result of nucleotide addition or elimination in homopolymer process. Conclusion: HSV-1 resistance against acyclovir is evolved from TK mutations, in the form of TK-negative, TK low-producing, and TK altered mutants, that are unable to phosphorylate TK and accordingly disrupt acyclovir phosphorylation to convert acyclovir triphosphate. Keyword : Acyclovir, Herpes simplex virus, Resistance, Thymidine kinase
IDENTIFICATION OF CANDIDA SPECIES IN DIABETIC PATIENTS WITH COATED TONGUE Hilda Hindasah; Yuti Malinda; Riani Setiadhi; Indah Suasani Wahyuni; Wahyu Hidayat; Nanan Nur’aeny
Dentino : Jurnal Kedokteran Gigi Vol 4, No 2 (2019)
Publisher : FKG Unlam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/dentino.v4i2.7068

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Background: Coated tongue is a condition in which the dorsum of the tongue is covered by a white layer containing food debris or microorganisms such as Candida species (Candida spp).  Factor that can influence coated tongue including a condition such as Diabetes  mellitus which often reduce the production of saliva and initiate the increase of Candida spp in number. Objective: to determine various species of Candida spp. in the saliva of Diabetes  mellitus patients with coated tongue as a preliminary condition to detect oral candidiasis. Methods: Coated tongue examination was performed by evaluating the lesion visually or using tongue scraper. Salivary collection was performed using oral rinse concentrate method. Saliva samples were inoculated in Chromogenic Agar to identify Candida spp. by examining the colour and the form of colony. Results: Eight samples (88.8%) were identified as C. albicans while C. parapsilosis was presented in 5 samples (66.6%) and C. tropicalis in 2 samples (22.2%). Overall, C. albicans is the most common Candida spp. that found in oral cavity. Candida spp. as normal flora in the oral cavity could be pathogen if the body's immune system decreases. In this study, there was a slight difference between Candida spp. found in the saliva of Diabetes mellitus patients compared to the control group. Conclusions: Candida spp. that identified in Diabetes  mellitus patients with coated tongue are C.albicans, C. glabrata, and C. tropicalis.
Management of chronic traumatic ulcer mimicking oral squamous cell carcinoma on the tongue Revi Nelonda; Riani Setiadhi
Dental Journal (Majalah Kedokteran Gigi) Vol. 51 No. 2 (2018): June 2018
Publisher : Faculty of Dental Medicine, Universitas Airlangga https://fkg.unair.ac.id/en

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/j.djmkg.v51.i2.p76-80

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Background: Traumatic ulcers represent the most common oral mucosal lesions that can be differentiated from oral squamous cell carcinoma (OSCC) by their clinical appearance. From a clinical perspective, OSCC may resemble a chronic traumatic ulcer (CTU) because the base of the CTU that is healing is filled with reddish-pink granulated tissue, similar to that in OSCC. Purpose: The aim of this case report is to provide information about the oral management of a CTU case that imitates OSCC. Case: A 30-year old female presented with a major, painful, non-healing ulcer located on the right lateral of the tongue for the previous two months. Approximately two years before, she had experienced a similar lesion on the tongue. Intra oral examination showed a 10mm x 5mm yellowish ulcer with a fibrous center, erythematous irregular-induration margin and concave yellow base. The 15th, 44th and 47th teeth were sharp and on occlusion caused trauma to the right lateral border of the tongue. Case management: Based on the clinical features, the lesion was imitating OSCC. After a case history review, clinical examination and appropriate investigation, the patient was diagnosed as suffering from a chronic traumatic ulcer. The primary treatment of traumatic ulcers involves eliminating etiological factors. As pharmacological therapy, a mixture of triamcinolone acetonide and 1mg dexamethasone tablet was administered in addition to folic acid and vitamin B12. Conclusion: Clinical presentation of traumatic lesions varies significantly and may, at times, be ambigous. It is important to immediately establish a correct diagnosis and implement prompt treatment of CTU lesions because they play a role at the oral carcinogenesis promotion stage.