Harum Puspita Ningrum
Pharmacy Department, Health Polytechnic of Tanjung Karang

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Potential Drug–Drug Interactions in Prescriptions for Outpatients with Type 2 Diabetes Mellitus at A Private Hospital in Bandar Lampung Harum Puspita Ningrum; Elma Viorentina Sembiring; Ageng Hasna Fauziyah
Formosa Journal of Science and Technology Vol. 5 No. 3 (2026): March 2026
Publisher : PT FORMOSA CENDEKIA GLOBAL

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55927/fjst.v5i3.20

Abstract

Diabetes is a chronic metabolic disease characterized by hyperglycemia, with type 2 diabetes mellitus (T2DM) being the most prevalent worldwide. This descriptive quantitative study aimed to identify potential drug–drug interactions (pDDIs) in T2DM outpatients. A total of 100 medical records from the outpatient department in 2024 were selected using accidental sampling. Most patients were female (57%) and aged 46–65 years (72%). Prescriptions commonly contained fewer than seven drugs (87%), with metformin being the most frequently prescribed antidiabetic (30.9%) and sulfonylureas the most common drug class (34.6%). Drug interactions were identified in 76% of prescriptions, predominantly of moderate severity (63.2%) and pharmacokinetic mechanism (50.6%)