Potential Drug–Drug Interactions in Prescriptions for Outpatients with Type 2 Diabetes Mellitus at A Private Hospital in Bandar Lampung

Harum Puspita Ningrum (Pharmacy Department, Health Polytechnic of Tanjung Karang)
Elma Viorentina Sembiring (Pharmacy Department, Health Polytechnic of Tanjung Karang)
Ageng Hasna Fauziyah (Pharmacy Department, Health Polytechnic of Tanjung Karang)

Formosa Journal of Science and Technology (FJST)
Vol. 5 No. 3 (2026): March 2026

Diabetes is a chronic metabolic disease characterized by hyperglycemia, with type 2 diabetes mellitus (T2DM) being the most prevalent worldwide. This descriptive quantitative study aimed to identify potential drug–drug interactions (pDDIs) in T2DM outpatients. A total of 100 medical records from the outpatient department in 2024 were selected using accidental sampling. Most patients were female (57%) and aged 46–65 years (72%). Prescriptions commonly contained fewer than seven drugs (87%), with metformin being the most frequently prescribed antidiabetic (30.9%) and sulfonylureas the most common drug class (34.6%). Drug interactions were identified in 76% of prescriptions, predominantly of moderate severity (63.2%) and pharmacokinetic mechanism (50.6%)