Dinastiti, Vide Bahtera
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Pengaruh Susu Kedelai terhadap Ekspresi Reseptor Estrogen-Β Uterus pada Masa Reproduksi Awal Rattus Norvegicus Betina: Effect of Soy Milk on Uterine Estrogen-Β Receptor Expression in the Early Reproductive Period of Female Rattus Norvegicus Dinastiti, Vide Bahtera; Nurdiana, Nurdiana; Dwijayasa, Pande Made
Jurnal Kebidanan Midwiferia Vol. 5 No. 1 (2019): April
Publisher : Universitas Muhammadiyah Sidoarjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21070/mid.v5i1.2619

Abstract

Receptors estrogen can also stimulated by other, namely by fitoestrogen. Fitoestrogen are the group of non steroid plants that have composition resembling the natural estrogen in the body. One of it is isoflavon, that can be binding with receptor estrogen, which affinity for RE-β is greater than RE-α and can make potential effect because receptors estrogen will blocked by isoflavon and cannot be occupied by estrogen.This compound can harm the endocrine system of the body because of the possible bad effects for reproductive function. Isoflavonoid is mostly found in soy. Soybean can be processed to soybean milk. The purpose of this study is demonstrate that administration of soy milk can affect the expression of RE-β uterus at the early reproductive period of female Rattus norvegicus. The method used is an experimental design post test control group design. The sample in this study is 24 Rattus norvegicus females. Then divided into four groups: one control group and three treatment groups were given soy milk each dose of 2.5 mg/kg/weight; 5mg/kg/weight; 10mg/kg/weight. The expression of RE-β uterus were measured by immunohistochemistry. Based on the analysis using ANOVA, was obtained p-value of 0.000, smaller than α = 0:05 (p <0.05). There is a significant influence on the administration of soy milk increase expression of RE-β and by LSD test obtained the results of differences from application of soy milk with different doses.
Hubungan Pengetahuan Ibu Hamil tentang HIV dengan Minat Untuk Periksa HIV (PMTCT): Relationship between knowledge of pregnant women about HIV and interest in HIV testing (PMTCT) Wardhani, Ratih Kusuma; Dinastiti, Vide Bahtera; Azizah, Eva Nur
Jurnal Kebidanan Midwiferia Vol. 5 No. 1 (2019): April
Publisher : Universitas Muhammadiyah Sidoarjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21070/mid.v5i1.2140

Abstract

This is due to the discovery of potent and safe vaccines against HIV infection and AIDS. The purpose of this study to determine the relationship of knowledge about HIV pregnant women with an interest to check HIV (PMTCT) in Health Center Gurah Kediri district. The research design used was cross sectional. The research site was conducted at Gurah Community Health Center, Gurah District, Kediri Regency and conducted in May - June 2017. The research samples were 30 respondents. It used Purposive sampling. The independent variable in this study is the knowledge of pregnant women about HIV. The dependent variable in this study is the interest of pregnant women to check for HIV. The instrument in this study used a questionnaire. The data analysys method was Spearman Rank by using SPSS. Knowledge of pregnant women about HIV most 17 respondents (56.7%) and a fraction less 5 respondents (16.7%) enough. Interest of the respondent to check HIV (PMTCT) do not interest most of 13 respondents (43.3%) and a small 8 respondents (26.7%) less interest. There is a relationship between knowledge of HIV pregnant women with an interest to check HIV (PMTCT) with Spearman Rank analysis value is 0.645 with a positive figure shows a strong relationship level. Knowledge greatly affect the interest in performing HIV (PMTCT). Pregnant women are expected to increase the knowledge by attending counseling given by health workers, especially tentag HIV so that it will increase the interest to check HIV (PMTCT).