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Cancer Profile in South Jakarta : A 5-year descriptive study Gondhowiardjo, Soehartati Argadikoesoema; Raharjo, Febryono Basuki; Hudiya, Elian; Priharto, R Koesmedi; Yekti, Widyastuti Endro
Radioterapi & Onkologi Indonesia Vol 9, No 2 (2018): Volume 9 No.2 Juli 2018
Publisher : Perhimpunan Dokter Spesialis Onkologi Radiasi Indonesia (PORI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (711.659 KB) | DOI: 10.32532/jori.v9i2.88

Abstract

There has been an effort of cancer registry in Cancer Control Program, especially Hospital-based, but it would not be useful if the data and procedure was not standardized. This study was a cross-sectional study with cancer data collected from every health facility in South Jakarta from 2017, April to May. Inclusion criteria was every patient that resided in South Jakarta from 2008, January 1st to 2012, December 31st with no exclusion criteria. Five most common cancers for male are hematopoietic and reticuloendothelial systems, nasopharynx, lung, lymph nodes, and liver cancer, respectively. Five most common cancers in female are breast, cervix uteri, ovarium, hematopoietic and reticuloendothelial systems, thyroid gland cancer, respectively. Cancer patients were comprised by female a lot more than male with 1.86:1 frequency comparison. Compared to data from Malaysia and Singapore in the same period of time, there were some differences in cancer profile between the countries. Based on the data reviewed, the quality was not perfect, one of the examples is shortcoming of SriKandi form which was used to input the data, especially occupation data. This can be a refinement point for future research and registry of cancer in Indonesia
The Association between D-dimer Concentration and Laboratory Parameters for Plasma Leakage in Dengue Infection Suwarto, Suhendro; Diahtantri, Riyanti Astrid; Hudiya, Elian
Jurnal Penyakit Dalam Indonesia Vol. 5, No. 3
Publisher : UI Scholars Hub

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Abstract

Introduction. Plasma leakage and activation of the coagulation system are the pathological hallmark of dengue hemorrhagic fever (DHF) that causes an increase in D-dimer concentration due to the degradation of fibrin clots. This study was conducted to determine the association between of D-dimer and laboratory parameters of plasma leakage, namely: thrombocytopenia, hypoalbuminemia, hemoconcentration and concentration serum glutamic oxaloacetic transaminase (SGOT) in dengue infected patients. Methods. A retrospective study was conducted at private hospitals in Jakarta, from December 2016 to March 2018. Patients >14 years with dengue infection and positive NS-1 were included in this study, and were classified into dengue fever (DF) group or DHF group. The Mann Whitney test was used for non-parametric variables and the Spearman test was used for the correlation for non-normally distributed numeric variables. Results. Seventy-three dengue infected patients included in this study consists of 29 (39.7%) female and 44 (60.3%) male. Total of 43 (58.9%) were classified as DD group, 30 (41.1%) were classified as DHF group. The D-dimer concentration of the DHF group in the fever phase was higher compared to the DD group (p = 0.004). There was a weak correlation in the fever phase between D-dimer concentration and the degree of thrombocytopenia (r = 0.35; p = 0.003) and weak inverse correlation in the fever phase between D-dimer concentration and albumin concentration (r = -0.34; p = 0.049). We found a weak correlation in the critical phase between D-dimer concentration and the degree of thrombocytopenia (r = 0.39; p = 0.034) and the moderate inverse correlation in the critical phase between the D-dimer concentration and albumin concentration (r = -0.43; p = 0.032). Conclusions. D-dimer concentrations in DHF patients in the fever phase are higher compare to DD patients. D-dimer concentration correlates with the degree of thrombocytopenia and hypoalbuminemia.