Article Per Year (5 Year)
p-Index From 2021 - 2026
0
P-Index
This Author published in this journals
All Journal Biosaintifika: Journal of Biology & Biology Education Bioedukasi: Jurnal Pendidikan Biologi
Sopandi, Didin
Unknown Affiliation
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Education Immunology & microbiology

Published : 2 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 2 Documents
Search

 1 
Effects of Kersen Juice and Lakum Leaf Extract on Lipid Profile of White Rats With Hyperlipidemia Sopandi, Didin; Saraswati, Tyas Rini; Yuniwarti, Enny Yusuf Wachidah
Biosaintifika: Journal of Biology & Biology Education Vol 11, No 3 (2019): Article-in-Press
Publisher : Department of Biology, Faculty of Mathematics and Sciences, Semarang State University . Ro

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15294/biosaintifika.v11i3.20813

Abstract

Kersen fruit and Lakum leaf contain substances that are potential as an antihyperlipidemic. The aim of this research was to analyze the effects of Kersen juice (Mutingia calabura L.) with dosage 0.2 ml/200 g BW and  lakum leaf extract (Cayratia trifolia L.) with dosage of 40 mg/200 g BW on lipid profile of white rats (Rattus norvegicus L.) with hyperlipidemia. This study used a Complete Randomized Design (CRD). This study used twenty adult male Wistar rats which were divided into five groups : P0 as a control group, P1 as a High Feed Diet (HFD) control group, P2 as a HFD group treated with Kersen juice with dosage of 0.2 ml/200 g BW, P3 as a HFD group treated with Lakum leaf extract with dosage of 40 mg/200 g BW and P4 as a HFD group treated with simvastatin. The treatments were given orally for 28 days. The parameters of this study were the level of cholesterol, HDL, LDL and triglyceride, as well as body weight, and food consumption. One-way ANOVA test was performed to determine the significant differences p<0.05 between groups followed by Duncan test with a 95% significant level. The results showed that compared to Kersen juice with dosage of 0.2 ml/200 g BW, administration of Lakum leaf extract with dosage of 40 mg/200 g BW was more effective in lowering cholesterol level, triglyceride and increasing HDL level, however, they were not effective in lowering LDL in rats with hyperlipidemia. This result shows that kersen and lakum leaf could be an alternative to prevent and avoid further effects of high cholesterol in people with hyperlipidemia.
The Effects of Kersen Juice (Mutingia calabura L.) and Lakum Leaf Extract (Cayratia trifolia L.) on Lipid Profile of White Rats (Rattus norvegicus L.) Hyperlipidemia Sopandi, Didin; Saraswati, Tyas Rini; Yuniwarti, Enny Yusuf Wachidah
Bioedukasi: Jurnal Pendidikan Biologi Vol 12, No 2 (2019): Bioedukasi: Jurnal Pendidikan Biologi
Publisher : Department of Biology Education Faculty of Teacher Training and Education Sebelas Maret Un

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20961/bioedukasi-uns.v12i2.34236

Abstract

Kersen fruit and Lakum leaf contain substances that are potential as an antihyperlipidemic. This study aimed to analyze The Effects of Kersen Juice (Mutingia calabura L.) with dosage 0.2 ml/200 g BW and Lakum Leaf Extract (Cayratia trifolia L.) with dosage 40 mg/200 g BW on Lipid Profile of White Rats (Rattus norvegicus L.) Hyperlipidemia. This study used a complete randomized design (CRD). Twenty adult male Wistar rats were divided into five groups, P0 as a control group, P1 as a HFD control group, P2 as a HFD group treated with Kersen juice with dosage 0.2 ml/200 g BW, P3 as a HFD group treated with Lakum leaf extract with dosage 40 mg/200 g BW and P4 as a HFD group treated by simvastatin. The treatments were given orally for 28 days. The parameters of this study were cholesterol level, HDL, LDL, triglyceride, body weight, and food consumption. One way ANOVA test was performed to determine the significant differences p<0.05 between groups followed by Duncan test with a 95% significant level. The results showed that compared to Kersen juice with dosage 0.2 ml/200 g BW, administration of Lakum leaf extract with dosage 40 mg/200 g BW was more effective in lowering cholesterol level, triglyceride and increasing HDL level, however, they were not effective in lowering LDL in rats with hyperlipidemia
Co-Authors Enny Yusuf Wachidah Yuniwarti Tyas Rini Saraswati