<![CDATA[Background: Indonesia is in the second place with the highest burden of tuberculosis (TB) in the world. Childhood is a period of rapid growth that requires efforts to maintain children's health. At the time the child still has a low immune system making it vulnerable to a disease including TB. The problem of TB in children requires better attention in child TB control programs. This study aimed to analyze the contextual influence of villages on the incidence of TB in children.Subjects and Method: This was a case-control study conducted in 25 villages in Surakarta, Central Java, from August to September 2019. A sample of 200 children aged 0 to 18 years was selected by fixed disease sampling. The dependent variable was the incidence of TB in children. The inÂdeÂpenÂdent variables were birth weight, BCG immunization, exclusive breastfeeding, nutritional staÂtus, parental income, home sanitation, exposure to cigarette smoke, family history of TB, and conÂÂtextual effect of village. Data on TB were obtained from medical record in SuÂÂrakarta community health center. The other data was collected by questionnaire. The data was analyzed by multilevel mulÂtiple logistic regression with Stata 13.Results: The risk of TB in children increased poor house sanitation (OR= 6.70; 95% CI= 1.14 to 39.27; p= 0.035), high exposure to cigarette smoke (OR= 6.71; 95% CI= 1.09 to 41.25; p= 0.040), and family history of TB (OR= 6.01; 95% CI= 1.36 to 26.39; p= 0.018). The risk of TB in children decreased with normal birth weight (≥2500 g) (OR= 0.12; 95% CI= 0.02 to 0.60; p= 0.009), BCG immunization (OR= 0.17; 95% CI= 0.04 to 0.64; p= 0.009 ), exclusive breastfeeding (OR= 0.08; 95% CI= 0.01 to 0.57; p= 0.011), good nutriÂtioÂnal status (OR= 0.11; 95% CI= 0.02 to 0.66; p= 0.016), and parental income ≥Rp 1,802,700 (OR= 0.07; 95% CI= 0.01 to 0.37; p= 0.002). Village had strong contextual effect on the risk of TB in children with intra-class correlation (ICC)= 29.24%.Conclusion: The risk of TB in children increases poor house sanitation, high exposure to cigarette smoke, and family history of TB. The risk of TB in children decreases with birth weight ≥2500 g, BCG immunization, exclusive breastfeeding, good nutriÂtioÂnal status, and high parental income. Village has strong contextual effect on the risk of TB in children.Keywords: Tuberculosis, risk factors, children aged 0-18 years, multilevel analysis.Correspondence: Dyah Ayu Saputri. Masters Program in Public Health, Universitas Sebelas Maret, Jl. Ir. Sutami 36 A, Surakarta, Central Java 57126. Email: ayusaputridyah7@gmail.com. Mobile: 081353236388.Journal of Epidemiology and Public Health (2019), 4(4): 361-372https://doi.org/10.26911/jepublichealth.2019.04.04.11 ]]>
