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All Journal Cermin Dunia Kedokteran
Sulistio, Bayu
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Health Professions

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Efektivitas Terapi Adjuvan Citicoline terhadap Perbaikan Kognitif Pasien Cedera Kepala Ramadhan, Syafira Elfa; Putri, Nikmatul Hikmah; Sulistio, Bayu; Sari, Fery Luvita
Cermin Dunia Kedokteran Vol 51 No 9 (2024): Kedokteran Umum
Publisher : PT Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55175/cdk.v51i9.980

Abstract

Background: Head injuries can reduce brain function with high morbidity. Several studies showed that citicoline may improve mild, moderate, and severe head injuries. Objective: To review the effectiveness of citicoline for cognitive improvement in head injury patients. Methods: Systematic search of 2 databases, ScienceDirect and Pubmed. Selected articles were then critically reviewed and analyzed. Results: Studies by Levin (1991) and Calatayud, et al, (1991) in Secades, et al. (2021); and Shokouhi, et al, (2014) showed that citicoline may improve cognitive function in adults and elderly with mild, moderate, and severe head injuries (p <0.05). Conclusion: Citicoline is effective in improving cognitive function in head injury patients.
Co-Authors Putri, Nikmatul Hikmah Ramadhan, Syafira Elfa Sari, Fery Luvita