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Modification of Screen Printed Carbon Electrode-Gold Nanoparticles (SPCE-AuNPs) for Detection of Mercury in Cosmetics Aini, Azizah Nurul; Nurul wahidah; Putriana Dwi Agustin; Dewi Nurmarlina; Ramadhan, Syafira Elfa; Riyanto
Indonesian Journal of Chemical Analysis (IJCA) Vol. 7 No. 2 (2024): Indonesian Journal of Chemical Analysis
Publisher : Universitas Islam Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20885/ijca.vol7.iss2.art8

Abstract

The cosmetics industry in Indonesia has experienced a significant increase of 12.6% from 2022 to June 2023, with 1025 industries having a positive impact on the Indonesian economy. Apart from that, it has triggered a number of naughty manufacturers to use dangerous chemicals in their cosmetic products such as mercury (Hg). Therefore, it is important to develop a fast and sensitive method for detecting mercury in cosmetics using SPCE-AuNPs. This research was carried out by synthesizing gold nanoparticles (AuNPs) using the reducing agent sodium citrate (Na3H5C6O7) with varying concentrations and characterization of several chemical instruments. Furthermore, SPCE was modified by AuNPs, its performance and application were tested to detect mercury in cosmetic cream using cyclic voltammetry (CV). SPCE-AuNPs provides an electrochemical response with higher oxidation and reduction peaks than bare SPCE with an oxidation peak at a potential of 0.1 V to 0.3 V and a reduction peak at -0.05 V to 0.05 V at a scan rate of 0.01 V/s to 0.03 V/s. This shows a good electrochemical response so it can be used for application to detection of mercury in cosmetic samples. The SPCE modified using AuNPs can potentially be used as a sensor for mercury detection in cosmetics.
Efektivitas Terapi Adjuvan Citicoline terhadap Perbaikan Kognitif Pasien Cedera Kepala Ramadhan, Syafira Elfa; Putri, Nikmatul Hikmah; Sulistio, Bayu; Sari, Fery Luvita
Cermin Dunia Kedokteran Vol 51 No 9 (2024): Kedokteran Umum
Publisher : PT Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55175/cdk.v51i9.980

Abstract

Background: Head injuries can reduce brain function with high morbidity. Several studies showed that citicoline may improve mild, moderate, and severe head injuries. Objective: To review the effectiveness of citicoline for cognitive improvement in head injury patients. Methods: Systematic search of 2 databases, ScienceDirect and Pubmed. Selected articles were then critically reviewed and analyzed. Results: Studies by Levin (1991) and Calatayud, et al, (1991) in Secades, et al. (2021); and Shokouhi, et al, (2014) showed that citicoline may improve cognitive function in adults and elderly with mild, moderate, and severe head injuries (p <0.05). Conclusion: Citicoline is effective in improving cognitive function in head injury patients.