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THE INHIBITION TEST OF FLAVONOID AND TANNIN IN NONI FRUIT (Morinda citrifolia Linn) COMPARED TO CEFTRIAXONE TOWARDS Escherichia coli IN VITRO Islamia, Tessa Swesty; Sutisna, Atik; Fitriani, Hikmah
Proceedings of the International Conference on Applied Science and Health No 4 (2019)
Publisher : Yayasan Aliansi Cendekiawan Indonesia Thailand (Indonesian Scholars' Alliance)

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (393.061 KB)

Abstract

Background: Escherichia coli is one of the causatives of infection agents. Noni fruit that contains the antibacterial ingredients was predicted as an alternative medicine to reduce the resistance of antibiotics. Noni fruit extract can inhibit the growth of Escherichia coli. The absence of research on the active substances contained in this fruit which plays a role in inhibiting the growth of Escherichia coli encourages the researcher to conduct this research.Methodology: The research was an experimental laboratory with post-test only control group design. The Escherichia coli grown on Mac conkey agar. Flavonoid and tannin in noni fruit (Morinda citrifolia Linn.) diluted with 3 concentrations, 50%, 70%, 100% and 2 control groups, positive control with ceftriaxone and negative control with Dimethylsulfoxide 10% (DMSO). The treatment group were incubated for 24 hours, then the inhibitory zone formed was measured in mm. Results: The Kruskall-Wallis test showed significant difference in all concentration. The results obtained from this research showed that the average of inhibition towards Escherichia coli on positive control (22.83 mm) had the largest inhibition zone among flavonoid 100% (18.83mm), flavonoid 70% (14.67 mm), flavonoid 50% (6 mm), tannin 100% (17.33 mm), tannin 70% (10.83 mm), tannin 50% (7.50 mm), and negative control (2 mm).Conclusion:  Flavonoid and tannin in noni fruit (Morinda citrifolia Linn) were effective for inhibiting the growth of Escherichia coli. The 100% concentration is the most effective concentration that can be promoted as an alternative medicine.
Pengaruh Support System Keluarga Terhadap Tingkat Kecemasan Pasien Dewasa yang Menjalani Operasi Herniorafi di RSUD Waled Ilhamsyah, Rizki; Sutisna, Atik; Priyatmoko, Donny Prasetyo
Syntax Literate Jurnal Ilmiah Indonesia
Publisher : Syntax Corporation

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36418/syntax-literate.v10i9.61607

Abstract

Support system keluarga merupakan sesuatu yang penting dalam mendukung kondisi psikologis pasien yang akan menjalani tindakan pembedahan. Dukungan bisa mencakup aspek emosional, fisik, dan informasi yang dapat membantu menurunkan tingkat kecemasan pasien sebelum menjalani operasi. Penelitian ini bertujuan menganalisis pengaruh support system keluarga terhadap tingkat kecemasan pasien dewasa yang menjalani operasi herniorafi di RSUD Waled, Cirebon. Metode penelitian menggunakan desain cross-sectional dengan pendekatan analitik prospektif. Sampel sebanyak 47 pasien diambil secara total sampling. Data dikumpulkan menggunakan kuesioner HARS untuk kecemasan dan kuesioner dukungan keluarga, lalu dianalisis dengan uji korelasi Spearman. Hasil penelitian menunjukkan terdapat hubungan negatif signifikan (r = -0,521; p=0,000) antara dukungan keluarga dengan tingkat kecemasan, artinya semakin tinggi dukungan keluarga, semakin rendah tingkat kecemasan pasien. Semua pasien menerima dukungan keluarga dan mengalami penurunan kecemasan. Implikasi dari penelitian ini adalah perlunya integrasi peran keluarga dalam program edukasi dan pendampingan praoperatif oleh tenaga kesehatan untuk mengurangi kecemasan pasien dan mendukung kesiapan mental sebelum operasi.