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The Description Of Allergic Contact Dermatitis At Gotong Royong I Primary Clinic Surabaya Purworizky, Dinar A; Harijati, Erna; Kartikawati, Lucia R
JOURNAL OF WIDYA MEDIKA JUNIOR Vol 1, No 3 (2019)
Publisher : FAKULTAS KEDOKTERAN UNIVERSITAS KATOLIK WIDYA MANDALA SURABAYA

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (300.391 KB) | DOI: 10.33508/jwmj.v1i3.2096

Abstract

Introduction : Allergies are one of the immune reaction caused by a substance called an allergen. One way an allergen may affect allergy sufferers is by direct contact. If after contact with an allergen sufferers experience changes in the skin, then those change is called allergic contact dermatitis. Aim: To describe the allergic contact dermatitis at Gotong Royong I Primary Clinic Surabaya. Methods : This study is a descriptive study. Data collected by recording the variables such as age, gender, source of allergens, pattern morphology, and the predilection area on data collector sheet based on the results of an examination by a doctor to patients with allergic contact dermatitis at Gotong Royong I Primary Clinic Surabaya in the period from June 13, 2016 until August 31, 2016. The sampling method is using total sampling technique. Result : This study showed on 53 patients. The highest age group was on a Toddlers group (0-5 years old) with 29 patients (54.7%). Women suffered allergic contact dermatitis more than men, as many as 30 patients (56.6%). Source of allergens mostly caused by cosmetics, as many as 15 patients (28.3%). Morphological pattern was mostly acute pattern, as many as 33 patients (62.3%). Predilection areas were located mainly in the area of the upper extremities, as many as 15 patients (28.3%). Conclusion : This study shows that more female subjects were diagnosed with allergic contact dermatitis by doctors. Allergic contact dermatitis in the subjects of the study was mostly caused by cosmetics
The Pathogenesis of Atopic Dermatitis: The Role of Filaggrin Tamarachiara Kuntjoro; Erna Harijati
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol. 29 No. 2 (2017): AGUSTUS
Publisher : Faculty of Medicine, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (321.059 KB) | DOI: 10.20473/bikk.V29.2.2017.164-167

Abstract

Background: Atopic dermatitis (AD) is a multifactorial skin disease with waxing and waning inflammatory process. In recent years, genetic mutations namely the null mutations of the filaggrin gene (FLG) has been the focus in AD risk factors investigations. Purpose: To highlight the emerging topic on the role of filaggrin as an important element in the pathogenesis of AD. Reviews: Filaggrin binds to cytoskeleton keratin to bring the physical strength to corneocytes. Filaggrin will be degraded to amino acids that conserve acidic pH and condensation of the skin. Patients with FLG null mutations are more likely to experience early-onset, severe and persistent AD. AD patients with FLG R501X null mutations are reported to be the least responsive to therapy. Conclusion: A filaggrin deficit is the main culprit in AD development that eventually leads to the defective skin barriers, reduction in natural moisturizing factors (NMF), infections and inflammation. FLG mutations associates with the phenotypes and course of AD which could be examined using Raman-determined NMF.
THE RELATIONSHIP BETWEEN SMOKING HABITS AND THE INCIDENCE OF CHRONIC URTICARIA IN CIVITAS WIDYA MANDALA CATHOLIC UNIVERSITY SURABAYA Harijati, Erna; Dian Putri, Maria Patricia; Tahalele, Paul L; Khoesasih, Antonius Kevin
JOURNAL OF WIDYA MEDIKA JUNIOR Vol 6, No 3 (2024): July
Publisher : FAKULTAS KEDOKTERAN UNIVERSITAS KATOLIK WIDYA MANDALA SURABAYA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33508/jwmj.v6i3.5760

Abstract

Background: Urticaria is a heterogeneous disease with multiple causative factors. A thorough literature research has revealed a very limited amount of evidence about the effects of smoking and alcohol consumption habits on the clinical characteristics of urticaria.. Atopic allergic which mean urticaria can affect all populations, but is most common in those aged between 20 to >60 years. Smoking has been reported to play a role in the onset of Urticaria. Substances in cigarette smoke can interact with body cells, resulting in the formation of free radicals or Reactive Oxygen Species (ROS).Objective: To see the relationship between smoking habit and the incidence of chronic urticaria among civitas at Widya Mandala Surabaya.Methods: The method used in this study was a case-control study by taking a population of civitas at the Widya Mandala Surabaya who had smoking history from 2020 to 2023. A sample of 94 people was obtained who had met the inclusion and exclusion criteria of the study. The sample of this study was divided into two groups consisting of a case group and a control group.Results: The results of the Contigency Coefficient Correlation test showed a significant p value of 0.031 <0.05, which means that there is an important correlation between smoking and the incidence of chronic urticaria among civitas at the Widya Mandala Surabaya.Conclusion: It is proven that there is a relationship between smoking and the incidence of chronic urticaria in civitas of Widya Mandala Surabaya.
PERSONAL HYGIENE AND THE INCIDENT OF SCABIES: COMPREHENSIVE CASE MANAGEMENT AT PHC SURABAYA HOSPITAL Harijati, Erna; Julian, Alvin
JOURNAL OF WIDYA MEDIKA JUNIOR Vol 6, No 1 (2024): January
Publisher : FAKULTAS KEDOKTERAN UNIVERSITAS KATOLIK WIDYA MANDALA SURABAYA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33508/jwmj.v6i1.5388

Abstract

Introduction: One of the risk factors for scabies is poor hygiene. Scabies is a skin condition caused by infestation and sensitization to the Sarcoptes scabiei var. hominis mite. While scabies can be treated, it is often diagnosed late, leading to delayed treatment and easy spread within groups.Objective: This paper aims to present a case of scabies in a patient who contracted the infection within the school environment, emphasizing the importance of hygiene and health awareness, particularly regarding skin health, to prevent disease transmission.Case Report: The patient presented to the Skin and Venereology Clinic at PHC Hospital with complaints of generalized itching persisting for 3 months, similar to symptoms experienced by classmates. The itching was accompanied by the presence of small ulcers. Treatment involved the application of Sulfur precipitatum Cream 10%, Krotamiton Cream 10%, and Permethrin Cream 5% once, to be left on for 8-10 hours (with a repeat application after 1 week), along with Cetirizine 10 mg.Conclusion: After weekly evaluations over 3 months, coupled with pharmacological therapy and adherence to hygiene practices, the patient returned symptom-free and without complications.