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All Journal Media Farmasi : Jurnal Ilmu Farmasi (Journal Of Pharmaceutical Science) JFIOnline INPHARNMED Journal (Indonesian Pharmacy and Natural Medicine Journal)
Setyaningrum, Ndaru
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Chemistry Health Professions Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Public Health

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ANALISIS FAKTOR YANG MEMPENGARUHI KEPATUHAN PENGAMBILAN OBAT PESERTA PROGRAM RUJUK BALIK DI BANDAR LAMPUNG Setyaningrum, Ndaru; Pramantara, I Dewa Putu
Jurnal Farmasi Indonesia Vol 9, No 1 (2017)
Publisher : Jurnal Farmasi Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (4801.067 KB) | DOI: 10.35617/jfi.v9i1.552

Abstract

ABSTRACT : Program (Program Rujuk Balik = PRB) through a health care program for the participants of the National Health Insurance with chronic diseases. Barriers to success of therapeutic treatment for patients with chronic diseases is non-adherence  related to the patient's treatment regimen. Taking medication adherence for patients with chronic illness is the first adherence can be assessed on how a person decides to get medicines for themselves. Analyzing factors affecting medication adherence taking participants PRB is important, cause non-adherence adverse effects appear in the treatment.  Participants adherence taking the drug on a PRB can be obtained from the data prescription claims to calculate the medication possession ratio (MPR), which MPR � 80% declared adherence. Data obtained from  prescription claim by participants PRB for  September 2015 until December 2015 in Bandar Lampung. Sample case study 82 people with diabetes. The calculation result MPR explains that 62.2% of respondents declared adherence taking medication, while 37.8% of respondents declared non-adherence. The results of the  logistic regression analysis, stating that there are influences together of factors respondents' knowledge, respondents belief, attitudes of personnel pharmacy services, pharmacy facilities, cost, availability of medication PRB, family support, and accessibility affect to respondent adherence of  taking medication. However, factors that significantly influence medication adherence refer the decision back is knowledge of respondents with sig = 0,028 (sig <0.05), belief of respondents with sig = 0,003 (sig <0.05), and accessibility sig = 0,044 (sig < 0.05) significantly affect to adherence  of taking medication.
KAJIAN KEAMANAN ANTIHIPERTENSI PASIEN GAGAL GINJAL KRONIK LANJUT USIA DI UNIT HEMODIALISA RSUP DR. SARDJITO YOGYAKARTA Setyaningrum, Ndaru; Pramantara, I Dewa Putu
Jurnal Farmasi Indonesia Vol 9, No 1 (2017)
Publisher : Jurnal Farmasi Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (569.783 KB) | DOI: 10.35617/jfi.v9i1.563

Abstract

ABSTRACT : The growth of elderly population increase fastest among the other age group. The elderly population been related to decrease renal function and other comorbidity as consequence of aging. The aim of this study is to know how about adverse drug reaction (ADR) and potential interaction of antihypertension drug in chronic kidney disease patient. This is a descriptive study about elderly patient with chronic kidney disease on period October 22th 2012 â?? January 22th 2013. This study use Naranjo scale to evaluate ADR and Tatro Drug Interactions Fact to evaluate potential drug interaction. There were 38 subjects analized, age < 70 years old (24 patients) and â?¥ 70 years old (14 patients); gender men (26 patients) and women (12 patients); duration hemodialysis < 8 months (8 patients) and â?¥ 8 months (30 patients); comorbidity DM (23 patients) and non DM (15 patients). There were probable ADR 4 events (10,8%) consist of nifedipine (2 events), lisinoprile (1 event) and captoprile (1 event). There were 14 events (37,8%) potential drug interactions consist of minor interaction (12 events) 32,4% and major interaction (2 events) 5,4%. This study show that there were actual probable ADR 10,8% and potential drug interaction 37,8%.  
TINGKAT PENGETAHUAN CIVITAS AKADEMIKA KESEHATAN DIBANDINGKAN NON KESEHATAN TENTANG KANKER SERVIKS DAN VAKSINASI HPV DI SLEMAN Setyaningrum, Ndaru; Zuar, Uzlah Fawati; Hadi, Ninisita Sri
Media Farmasi: Jurnal Ilmu Farmasi Vol. 16 No. 2: September 2019
Publisher : Universitas Ahmad Dahlan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.12928/mf.v16i2.14296

Abstract

Kanker serviks merupakan jenis kanker yang menimbulkan kematian tertinggi pada wanita. Tingkat pengetahuan mahasiswa mengenai kanker serviks dan vaksinasi HPV masih tergolong rendah. Penelitian ini bertujuan untuk mengetahui tingkat pengetahuan civitas akademika kesehatan dibandingkan non kesehatan tentang kanker serviks dan vaksinasi HPV di Sleman Yogyakarta. Penelitian ini merupakan jenis penelitian deskriptif dengan pendekatan cross sectional. Pemilihan sampel menggunakan teknik cluster random sampling untuk menentukan jurusan dan perguruan tinggi di Kabupaten Sleman. Pengambilan data dilakukan menggunakan kuesioner pada bulan Agustus - September 2016. Subjek penelitian terdiri dari civitas akedemika kesehatan 120 responden dan non kesehatan 80 responden. Analisis data dilakukan secara univariat dan bivariat. Tingkat pengetahuan diolah secara deskriptif sedangkan perbedaan tingkat pengetahuan antara civitas akademika kesehatan dan non kesehatan dilakukan uji Mann Whitney. Sejumlah 8 (6,67%) responden kesehatan sudah melakukan vaksinasi HPV. Rata - rata tingkat pengetahuan civitas akademika bidang kesehatan lebih baik dibandingkan non kesehatan. Tingkat pengetahuan kategori baik terkait kanker serviks dan vaksinasi HPV untuk responden kesehatan berturut - turut 90(74,69%) dan 87 (72,22%) sedangkan non kesehatan berturut - turut 53 (66,41%) dan 52 (64,79%). Sebagian besar responden kesehatan (90,28%) dan non kesehatan (88,75%) memiliki persepsi positif terhadap vaksinasi HPV. Tingkat pengetahuan responden kesehatan mengenai kanker serviks dan vaksinasi HPV lebih baik dibandingkan responden non kesehatan, namun tidak berbeda signifikan secara statistik (p>0,05).
KAJIAN PENGGUNAAN OBAT OFF-LABEL PADA ANAK DI PUSKESMAS SLEMAN Akbar, Rizki; Setyaningrum, Ndaru; Estiningsih, Daru
INPHARNMED Journal (Indonesian Pharmacy and Natural Medicine Journal) Vol. 1 No. 1 (2017)
Publisher : Alma Ata University Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21927/inpharnmed.v1i1.501

Abstract

AbstrakOff-label merupakan istilah singkat yang menjelaskan penggunaan obat diluar ketentuan yang berkaitan dengan dosis, kelompok usia, rute pemberian, dan indikasi yang berbeda. Penggunaan obat off-label pada anak terjadi karena tidak lengkapnya data farmakokinetik, farmakodinamik, dan efek samping dari suatu obat karena penelitian klinik pada anak cukup sulit dan tidak sesuai dengan etika dan moral penelitian. Penelitian yang digunakan dalam penelitian ini adalah deskriptif dengan pengambilan data dilakukan secara retrospektif. Data prevalensi penggunaan off-label pada anak diperoleh dengan melakukan telaah catatan medik anak di Puskesmas Sleman selama periode tahun 2015. Selain kajian obat off-label dilakukan juga pengelompokan obat berdasarkan sistem klasifikasi ATC (Anatomical Therapeutic Chemical). Berdasarkan hasil penelitian dari 100 sampel rekam medis pasien anak usia 0-18 tahun selama tahun 2015 terdapat obat-obat off-label sebanyak 25 kasus (8,41%), yang terdiri dari 12 kasus (4,04%) off-label cara pemberian, 8 kasus (2,69%) off-label indikasi, dan 5 kasus (1,68%) off-label usia. Sedangkan untuk kategori off-label dosis dan off-label kontraindikasi tidak ditemukan adanya kasus off-label. Obat yang paling banyak diresepkan secara off-label adalah golongan obat saluran napas sebanyak 13 penggunaan (4,38%) yaitu salbutamol, dan gliseril guaiakolat. Kata Kunci: Obat off-label, Anak, Puskesmas Sleman, ATC. AbstractOff-label is a term to decscribe the usage of drugs agaisnt the regulations in accordance to doses, age groups, distribution routes, and diverse indications. The usage of off-label drugs on children is caused by incomplete pharmacokinetic data, pharmacodynamic, and as a result of side effects due to clinical studies on children are quite complex and incorresponding with ethics and moral of the studies. Method used in this study was evaluative-descriptive using retrospective approach in data collection. Prevelance data of the usage of off-label drugs on children was gathered by examining the children medical records in Sleman Community Health Center within the time period of 2015. Besides research on off-label drug, drug categorization was also done based on the ATC Classification system (Anatomical Therapeutic Chemical). Based on the result of the research, out of 100 sample of patient medical record of the age 0-18 years along 2015, there has been 25 cases of off-label medicines (8,41%), in which 12 cases (4,04%) was distribution way off-label, 8 cases (2,69%) indicated off label, and 5 cased (1.68%) age off-label. While for the category of dose off label and contraindication off label has not been found any case. The most common off label prescription was respiratory drugs of 13 use (4,38%) that is salbutamol, and glyceril guaiacolat. Keyword: Off-label drugs, Children, Sleman Community Health Center, ATC.
Co-Authors Estiningsih, Daru I Dewa Putu Pramantara Ninisita Sri Hadi Rizki Akbar, Rizki Zuar, Uzlah Fawati