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Hutagaol, Lungguk
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Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemistry Education Health Professions Library & Information Science Medicine & Pharmacology Other

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DISOLUSI KAPSUL TEOFILIN DALAM MODEL RACIKAN RESEP DOKTER Hutagaol, Lungguk; Irwan, Yenny
Jurnal Farmasi Indonesia Vol 5, No 1 (2010)
Publisher : Jurnal Farmasi Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35617/jfi.v5i1.35

Abstract

Theophylline is asthma treatment that quite a lot used and have narrow therapy scope and is often combined with ephedrine hidrochloride in doctorâ??s prescription. Recently handling compounding the  prescription is  in highly varied and this condition has influenced dissolution rate. In consequence, conducted research hits difference dissolution capsule from compounding that indigenous to active ingredient and from tablet that triturated become powder. Despitefully, conducted research hits influence ephedrine hydrochloride to theophylline dissolution rate. The result can be concluded that formed compounding from powder produces super ordinate dissolution are compared to compounding from combination of  theophylline and ephedrine hydrochloride tablet. So compounding from theophylline and ephedrine hydrochloride tablet is inadvisable because they decrease theophylline dissolution rate. ABSTRAK Teofilin merupakan obat asma yang cukup banyak digunakan dan mempunyai lingkup terapi  sempit serta sering dikombinasi dengan efedrin hidroklorida dalam racikan resep dokter. Saat ini penanganan racikan resep dokter di apotek  sangat  bervariasi dan hal ini berpengaruh pada kerapatan mampat yang akhirnya mempengaruhi kecepatan disolusi. Oleh karena itu dilakukan penelitian mengenai perbedaan disolusi kapsul racikan yang berasal dari bahan baku serbuk dan dari tablet yang digerus menjadi serbuk. Di samping itu, dilakukan penelitian mengenai pengaruh efedrin hidroklorida terhadap disolusi kapsul teofilin. Dari hasil penelitian dapat disimpulkan bahwa kapsul yang diracik dari bahan baku serbuk menghasilkan disolusi yang lebih tinggi dibandingkan dengan kapsul yang diracik dari bentuk  tablet. Oleh karena itu racikan dari tablet  teofilin dan efedrin hidroklorida  tidak disarankan karena menurunkan laju disolusi teofilin.
Pembuatan Sabun Padat Transparan Menuju Santri yang Memiliki Jiwa Kewirausahaan Prasetiyo, Andri; Yantih, Novi; Yamin, Muhamad; Hutagaol, Lungguk; Nawasiah, Nana
SULUH: Jurnal Abdimas Vol 4 No 1 (2022): SULUH: Jurnal Abdimas Agustus
Publisher : FEB-UP Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35814/suluh.v4i1.3418

Abstract

Community service on counseling and assistance in making solid soap has been carried out at the Al-Amien Islamic Boarding School, Tangerang. This activity was attended by students and junior high school students, senior high school students and the general public. Participants were given knowledge and training regarding the process of preparing, manufacturing, storing and marketing transparent solid soap digital products from palm kernel oil. The quality of the transparent solid soap produced will be tested and compared with the transparent solid soap on the market. This activity is expected to increase the entrepreneurial spirit of the santri so that it can be an opportunity to start a business and meet the soap needs in Islamic boarding schools. This activity is carried out online and offline in the form of workshops with counseling/lectures and practices. This activity needs to be monitored, mentoring and mentoring for future businesses. The resulting transparent solid soap has a pH of 8.43-8.45, a hardness of 34.3-34.4 10-1mm, water content 21.45-21.89%, free fatty acids 0.94-0.98% and 1.74- 1.95%. Transparent solid soap made to meet quality requirements and in accordance with transparent comparison soaps on the market. Keywords: community service, transparent solid soap, palm kernel oil
Formulation of Transparent Solid Soap from Palm Kernel Oil Prasetiyo, Andri; Hutagaol, Lungguk; Luziana, Lidya
Jurnal Jamu Indonesia Vol. 5 No. 2 (2020): Jurnal Jamu Indonesia
Publisher : Tropical Biopharmaca Research Center, IPB University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29244/jji.v5i2.159

Abstract

Palm kernel oil contains fatty acids, especially lauric acid at 46-52%. Lauric acid has the properties of hardening, cleaning, producing foam and softening that is needed in making soap. The purpose of this study is to make transparent solid soap from a combination of glycerin, sucrose, and ethanol 96% as a transparent agent that meets the requirements of quality tests and organoleptic tests. Made 9 (nine) formulas with some combination of glycerin, sucrose, ethanol 96% by a semi-boiled method that is mixing palm kernel oil and stearic acid which has been melted at 60˚C, then adding 30% NaOH, stirring at 70- 80˚C. Transparent agent and other additives are mixed into the soap mass obtained from the saponification process, then poured into a soap mold and carried out a curing process for 2 weeks. The result of this research is obtained a transparent yellow solid soap that is the bright and distinctive smell of coconut perfume with a pH of 8.35-8.64, the hardness of 21.30-38.13 10-1 mm, moisture content of 21.48-33.33%, free fatty acid content 0,88-0,96%, unsaturated fat content 1,45-2,38%, surface tension 27,93-32,34 dyne/cm. Transparent solid soap that meets the quality requirements and the organoleptic test is formula A with PH 8.64, hardness 25.80 10-1 mm, moisture content 25.55%, free fatty acids 0,94%, unsaturated fat 1,45%, surface tension 30.02 dyne/cm.
Co-Authors Andri Prasetiyo Irwan, Yenny Luziana, Lidya Muhamad Yamin Nawasiah, Nana Novi Yantih