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DIFFERENCES OF BIRTH WEIGHT AND ONSET OF ACHOLIC STOOL BETWEEN EXTRAHEPATIC AND INTRAHEPATIC CHOLESTASIS Setyoboedi, Bagus; Situmorang, Lasmauli; Prihaningtyas, Rendi Aji; Arief, Sjamsul
Indonesian Midwifery and Health Sciences Journal Vol. 8 No. 2 (2024): Indonesian Midwifery and Health Sciences Journal, April 2024
Publisher : UNIVERSITAS AIRLANGGA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/imhsj.v8i2.2024.93-101

Abstract

Background: Biliary atresia (extrahepatic cholestasis) and neonatal hepatitis (intrahepatic cholestasis) are two main causes of cholestasis. It is important to distinguish the type of cholestasis for determine management. Patient with intrahepatic cholestasis have birth weight lower than extrahepatic cholestasis. Onset of acholic stool in extrahepatic cholestasis usually appear in 15-30 days of first life. The aim of the study to identify differences of birth weight and onset of acholic stool between the type of cholestasis. Method: A retrospective study on cholestasis children aged under 2 years was conducted at Dr. Soetomo General Academic Hospital from January 2012 to December 2016. A thorough history of birth weight and onset of acholic stool were undertaken. Based on histopatology liver biopsy patients were classified into twogroups: I (extrahepatic cholestasis) and II (intrahepatic cholestasis). Result: Statistical analysis of Mann Whitney U was used with p<0.05 being significant. A total of 84 children were included, 55% were male. 40 children suffered from extrahepatic cholestasis (mean age 4.8 ± 2.6 months old) and 44 children suffered from intrahepatic cholestasis (mean age 2.9 ± SD 3.8 months old). The mean birth weight between extrahepatic and intrahepatic cholestasis were 2813 ± 704 gram vs 2717 ± 577 gram) (p=0.29). The mean onset of acholic stool between extrahepatic and intrahepatic cholestasis were 43.0 ± 60.6 days vs 26.6 ± 39.7 days (p=0.27). Conclusion : There is no difference of birth weight and onset of acholic stool between extrahepatic and intrahepatic cholestasis.
Risk Factor of Low-Birth-Weight Baby Prevalence at Fakfak Public Hospital West Papua Amelia, Dian Rizky; Situmorang, Lasmauli
Jurnal Medis Islam Internasional Vol 3 No 2 (2022): June
Publisher : UNUSA Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33086/iimj.v3i2.2770

Abstract

Background: The high number of infant mortality rate in Indonesia relate to Low Birth Weight (LBW) babies that be a problem of public health sector. LBW babies are facing several health problems such as various diseases that arise in the first six days of life, and can experience long-term problems such as impaired development and growth. This is inseparable from the mother's risk factors during pregnancy. West Papua Province contributes 23.8% of LBW cases in Indonesia. Fakfak District Hospital as the only referral hospital in West Papua Fakfak district still has many problems related to cases of low birth weight babies. Objective: To know the risk factors of LBW prevalence based on maternal age, gestational age, parity, hemoglobin levels, premature rupture of membranes (PROM), and preeclampsia in Fakfak public hospital, West Papua. Methods: This study is an observational analytic with cross sectional study in Fakfak public hospital during April 2021 till October 2021. Purposive sampling method used to obtain the samples from medical records that fit to inclusion and exclusion criteria (N=418). Data was analyzed with SPSS statistic for Mac used Chi-square test and logistic regression method.  The significant level of the test was p < 0,05. Results: A total of 418 newborn were included during study period. There were significant results in gestasional age (p=0,000) (OR 7,23, CI95% 1,13-10,4), premature rupture of membranes (PROM) p=0,000 (p<0,05) OR 14,23 (CI95% 7,7-26,2), hemoglobin levels (p=0,000) (OR 3,47 CI95% 1,99-6,03), preeclampsia (p=0,000) (OR 9,76 CI95% 5,39-17,6). The regression test showed significant result at four variables. Conclusion: Gestational age, PROM, hemoglobin levels, and preeclampsia are risk factors that significant lead to LBW prevalence in Fakfak public hospital, West Papua.