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All Journal Jurnal Kesehatan Andalas Wal'afiat Hospital Journal WAL'AFIAT HOSPITAL JOURNAL
Asseggaf, Syarifah NYRS
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Dentistry Health Professions Medicine & Pharmacology Nursing Public Health Veterinary

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Analisis Kandungan Metabolit Sekunder, Antioksidan dan Uji Aktivitas Antibakteri Minuman Tradisional Serbat Khas Kalimantan Barat dengan Variasi Komposisi dan Lama Perendaman Asseggaf, Syarifah NYRS; Zakiah, Mistika; Ulfah, Ridha
Jurnal Kesehatan Andalas Vol. 11 No. 2 (2022): Online July 2022
Publisher : Faculty of Medicine, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jka.v11i2.1925

Abstract

Serbat drink is a traditional drink typical of the Malay of West Kalimantan made from plant spices usually served in the Saprahan tradition. Serbat drinks are widely circulated among the public because, empirically, they are useful for health problems, one of which is to treat diarrhea. Objectives: To analyzed the content of secondary metabolites, antioxidant activity, and antibacterial activity of serbat drink on the growth of Escherichia coli bacteria which were known from the presence or absence and measurement of the length of the inhibition zone (the clear area around the disc) with the positive control, namely ciprofloxacin, and negative control, namely distilled water. Methods: The plant spices used in this research include cardamom, cloves, star anise, cinnamon, pandan leaves, sappan wood, anise, and ginger. Serbat drink was made in 3 variations, namely composition A, composition B, and composition C. The three composition variations were carried out for two soaking times, namely 15 minutes and 540 minutes. This study used the thin-layer chromatography (TLC) method for phytochemical screening, the DPPH (2,2-diphenyl-1-pikrilhidrazil) method for examination of antioxidant activity, and Escherichia coli bacteria cultured in 3 agar and tested using the disc diffusion method (Kirby-Bauer) to determine its antibacterial activity.  Results: The secondary metabolites contained in each serbat water sample, antioxidant activity from strongest to weakest among the serbat samples, and the absence of visible inhibition zones. Conclusion: Serbat drink does not have antibacterial activity against Escherichia coli.Keywords:  secondary metabolites, serbat drink, variations in composition, variations in the soaking time
Analisis Interaksi Obat pada Pasien Hipertensi di Posyandu Lansia Lembaga Kartini Surya Khatulistiwa Tanjung Hilir Anggraeny, Raine Ardhita; Asseggaf, Syarifah NYRS; Nurmainah, Nurmainah
Wal'afiat Hospital Journal Vol 6 No 1 (2025): Wal'afiat Hospital Journal
Publisher : Rumah Sakit Ibnu Sina, Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/whj.v6i1.159

Abstract

Polypharmacy of drugs in elderly hypertensive patients cannot be avoided because the elderly have several diseases other than hypertension. Polypharmacy administration of drugs can increase the potential for drug interactions to occur at a major, moderate or minor level, as well as occur in the pharmacodynamic or pharmacokinetic phase. One way that can be done to reduce these risks is by administering the right medication and minimizing the administration of polypharmacy for hypertensive patients. The research to analyze interactions between drugs, classify antihypertensive drugs, describe the percentage of drug interactions, and the severity of drug interactions given to elderly hypertensive posyandu patients at the Kartini Surya Khatulistiwa Tanjung Hilir Society. Observational with a descriptive model of the cross-sectional study. The sample used in this study is 36 hypertensive patients at the Posyandu Lansia Lembaga Kartini Surya Khatulistiwa Tanjung 2019. This research was conducted from March-April 2021. Samples are selected using Consecutive Sampling (nonprobability sampling). 79 cases interaction drug of hypertension patients in Posyandu Lansia Lembaga Kartini Surya Khatulistiwa Tanjung Hilir Drug interactions that occurred moderate level were 47 cases (59%) and pharmacodynamic stage in 71 cases (90%).
Analisis Interaksi Obat pada Pasien Hipertensi di Posyandu Lansia Lembaga Kartini Surya Khatulistiwa Tanjung Hilir Anggraeny, Raine Ardhita; Asseggaf, Syarifah NYRS; Nurmainah, Nurmainah
Wal'afiat Hospital Journal Vol 6 No 1 (2025): Wal'afiat Hospital Journal
Publisher : Rumah Sakit Ibnu Sina, Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/whj.v6i1.159

Abstract

Polypharmacy of drugs in elderly hypertensive patients cannot be avoided because the elderly have several diseases other than hypertension. Polypharmacy administration of drugs can increase the potential for drug interactions to occur at a major, moderate or minor level, as well as occur in the pharmacodynamic or pharmacokinetic phase. One way that can be done to reduce these risks is by administering the right medication and minimizing the administration of polypharmacy for hypertensive patients. The research to analyze interactions between drugs, classify antihypertensive drugs, describe the percentage of drug interactions, and the severity of drug interactions given to elderly hypertensive posyandu patients at the Kartini Surya Khatulistiwa Tanjung Hilir Society. Observational with a descriptive model of the cross-sectional study. The sample used in this study is 36 hypertensive patients at the Posyandu Lansia Lembaga Kartini Surya Khatulistiwa Tanjung 2019. This research was conducted from March-April 2021. Samples are selected using Consecutive Sampling (nonprobability sampling). 79 cases interaction drug of hypertension patients in Posyandu Lansia Lembaga Kartini Surya Khatulistiwa Tanjung Hilir Drug interactions that occurred moderate level were 47 cases (59%) and pharmacodynamic stage in 71 cases (90%).
Co-Authors Anggraeny, Raine Ardhita Mistika Zakiah Nurmainah Nurmainah Ridha Ulfah