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All Journal Sainstek : Jurnal Sains dan Teknologi Jurnal Katalisator JIKA Science: Indonesian Journal of Science
Suriani, Endang
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Agriculture, Biological Sciences & Forestry Chemistry Computer Science & IT Health Professions Immunology & microbiology Mathematics Medicine & Pharmacology Neuroscience Nursing Physics Public Health Other

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GAMBARAN HASIL PEMERIKSAAN TROMBOSIT DARAH PADA PENDERITA DBD SESUDAH MENGKONSUMSI JAMBU BIJI (psidium guajava) DI RST SOLOK TAHUN 2018 Marisa, Marisa; Suriani, Endang
Sainstek : Jurnal Sains dan Teknologi Vol 11, No 2 (2019)
Publisher : IAIN Batusangkar

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (280.148 KB) | DOI: 10.31958/js.v11i2.1604

Abstract

Dengue or dengue fever is the most dominant disease suffered by the people of Indonesia. It can be detected through hematocrit values and platelet counts of patients. Usually, the patient's hematocrit value increases and blood plasma volume decreases. On the other hand, the platelet count of the patient decreases due to bone marrow suppression and the presence of antibodies against platelet deficiency. The purpose of this study was to determine the hematocrit value and platelet count of patients with dengue fever. This study was conducted on 10 patients with dengue fever at the Solok Army Hospital in the December 2018 - January 2019 period. The results of this study found that the total platelet count of patients when starting treatment was 38,300 cells / mm3. While the mean hematocrit when starting treatment is 43.5%. It can be concluded that dengue fever sufferers have increased hematocrit values and decreased platelet counts.
PERBEDAAN KADAR UREUM DAN KREATININ SEBELUM DAN SESUDAH HEMODIALISIS PADA PASIEN GAGAL GINJAL KRONIS DI RSUD PANYABUNGAN marisa, Marisa; Suriani, Endang; Renowati, Renowati; Susanto4, Vetra; Saidah, Rini
Jurnal Ilmu Kesehatan Abdurrab Vol 1 No 3 (2023): Volume 1 Nomor 3 September 2023
Publisher : LPPM Universitas Abdurrab

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Abstract

The kidneys are important organs in the human body that have the main function to excrete the rest of the body's metabolism such as urea and creatinine. Chronic kidney disease is a disorder of kidney structure or a progressive and irreversible decline in kidney function. The purpose of this study was to determine how the results of ureal levels and creatinine levels before and after hemodialysis in kidney failure patients at Panyabungan Hospital. This study used analytical methods with a cross-sectional research design with a sample size used in total sampling as 34 samples. Based on the results of a study of 34 samples, the average ureal level before hemodialysis was 180.24 mg / dL and the average ureal level after hemodialysis was 94.29 mg / dL, the average creatinine level before hemodialysis was 3.682 mg / dL and the average creatinine level after hemodialysis was 1.785 mg / dL. The conclusion of the study was that ureal levels before hemodialysis were obtained increased. Ureal levels after hemodialysis were obtained the most, namely on the criteria increased by 22 people (64.7%), normal 12 people (35.3%). Creatinine levels before hemodialysis are obtained in an elevated state. Creatinine levels after hemodialysis were obtained the most, namely on the criteria increased by 22 people (64.7%) and normal 12 people (35.3%). Indepent T test obtained sig. (2tailed) is 0.000, meaning that there is a significant and significant difference between ureal levels and creatinine levels before and after hemodialysis in chronic renal failure patients at RSUD Panyabungan
THE REMAINING CHEMICAL COMPOUNDS OF THE BODY'S METABOLISM ARE REDUCED THROUGH THE HEMODIALYSIS METHOD Susanto, Vetra; Dewi AS, Mutia; Suryani, Suryani; Suriani, Endang; Dasa Wardhani, Sri Muri
JURNAL KATALISATOR Vol. 10 No. 1 (2025): Jurnal Katalisator ( On Progres)
Publisher : LLDIKTI X Sumbar, Riau, Jambi, Kepri

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62769/katalisator.v10i1.3450

Abstract

The accumulation of metabolic residual chemical compounds, such as urea, and creatinine, is a major consequence of decreased glomerular filtration function in patients with chronic kidney disease (CKD). Increased concentrations of these compounds trigger internal homeostasis disorders and accelerate the progression of metabolic complications. Hemodialysis is a kidney replacement therapy that aims to eliminate toxic compounds and maintain the body's biochemical balance. The purpose of this study is to evaluate the effectiveness of hemodialysis in reducing urea, creatinine, and uric acid levels in CKD patients. The pre-post test research involved 30 stage V CKD patients who underwent routine hemodialysis at the Regional General Hospital (RSUD) Padang Panjang, West Sumatra. Venous blood samples were taken 15 minutes before and after a single hemodialysis session. Urea levels were analyzed using the urease-GLDH method, creatinine using the kinetic Jaffé method, and uric acid using the uricase-POD method. The data were analyzed using a paired t-test with a significance level of p<0.05.The results were obtained The average urea level decreased from 182.6 ± 28.7 mg/dL it was concluded that Hemodialysis significantly reduced the level of chemical compounds left over from the body's metabolism in patients to 76.3 ± 16.9 mg/dL (p<0.001), creatinine from 11.8 ± 2.9 mg/dL to 4.9 ± 1.3 mg/dL (p<0.001), and uric acid from 8.5 ± 1.8 mg/dL to 5.2 ± 1.1 mg/dL (p<0.001). It can be concluded that hemodialysis significantly reduces the level of chemical compounds left over from the body's metabolism in advanced CKD patients. Hemodialysis maintains biochemical homeostasis and reduces the risk of systemic complications.
Perbandingan Kreatinin Klirens Sebelum dan Sesudah Kemoterapi pada Pasien Kanker Paru di RSUD Arifin Achmad Pekanbaru Marisa, Marisa; Mayaserly, Dina Putri; Permatasari, Rita; Lestari, Rinda; Suriani, Endang; della, Winda Afrian
Science: Indonesian Journal of Science Vol. 2 No. 4 (2025)
Publisher : LPPI Yayasan Almahmudi bin Dahlan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/science.v2i4.301

Abstract

Kanker paru adalah tumor ganas paru yang berasal dari saluran napas atau epitel bronkus, yang ditandai dengan pertumbuhan sel yang tidak normal. Tatalaksana kanker paru mencakup beberapa metode, seperti kemoterapi, pembedahan, dan radioterapi. Penelitian ini bertujuan untuk mengetahui perbandingan kreatinin klirens sebelum dan sesudah dikemoterapi pada pasien kanker paru di RSUD Arifin Achmad Pekanbaru. Penelitian ini menggunakan desain observasional analitik dengan pendekatan cross – sectional. Sebanyak 30 pasien kanker paru di RSUD Arifin Achmad yang dipilih sebagai koresponden dan diperoleh dari hasil pemeriksaan laboratorium sebelum dan sesudah kemoterapi . Uji normalitas data menggunakan uji shapiro wilk dengan hasil p value = < 0.05 yang menunjukkan bahwa data tidak berdistribusi normal. Hubungan antara kreatinin klirens sebelum dan sesudah kemoterapi dianalisis menggunakan korelasi pearson, dengan nilai r = 0.412 yang menunjukkan hubungan sedang. Hasil penelitian ini menunjukkan adanya penurunan dan peningkatan kadar kreatinin klirens pada pasien kanker paru yang sudah melakukan kemoterapi. berdasarkan hasil penelitian dapat disimpulkan rata -rata kadar kreatinin klirens sebelum kemoterapi 100.07 mL/min, dan sesudah kemotherapy yaitu 104.01 mL/min. Terdapat perbedaan antara kreatinin klirens sebelum dan sesudah kemoterapi.
Co-Authors Dasa Wardhani, Sri Muri della, Winda Afrian Dewi AS, Mutia Lestari, Rinda Marisa Marisa Marisa Marisa Mayaserly, Dina Putri Permatasari, Rita Renowati, Renowati Saidah, Rini Suryani Suryani Susanto, Vetra Susanto4, Vetra