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All Journal Jurnal Riset Kesehatan Nasional Jurnal Farmasi Galenika
WULANDARI, SARAH
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Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health

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KUALITAS HIDUP PASIEN KANKER PAYUDARA: SETTING RAWAT JALAN WULANDARI, SARAH
Jurnal Riset Kesehatan Nasional Vol 3, No 2 (2019)
Publisher : Institute Teknologi dan Kesehatan (ITEKES) Bali

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (347.642 KB) | DOI: 10.37294/jrkn.v3i2.179

Abstract

Jumlah untuk kasus kanker di Indonesia, kasus baru dan angka kematian tertinggi ditempati oleh kanker payudara. Proses pengobatan yang salah satunya adalah kemoterapi secara spesifik dilaporkan dapat mempercepat penuaan dan penurunan kemampuan kognitif yang dapat merujuk pada perubahan kondisi kualitas hidup pasien. Tujuan penelitian ini adalah untuk mengetahui kondisi kualitas hidup pasien kanker payudara yang telah menjalani kemoterapi. Penelitian deskriptif dengan pendekatan potong lintang dan pengambilan sampel secara purposive ini mendapatkan 53 responden perempuan kanker payudara dengan rentang umur 20-70 tahun. Alat pengumpul data menggunakan kuesioner. Hasil analisa menunjukkan kondisi kualitas hidup responden mayoritas berada pada kondisi cukup s.d. baik (9-16) dari rentang 0-16. Kondisi ini diharapkan agar pasien kanker payudara yang masih bias ditingkatkan kualitas hidupnya diberikan intervensi sesuai kebutuhan. Penelitian terkait kualitas hidup dengan komponen yang lebih kompleks juga dapat dikembangkan pada penelitian mendatang.
Antimicrobial Candidate From Ethanol Extract And Ethyl Acetate Fraction Of Betadin (Jatropha multifida L.) Leaves Which Actively Inhibits Clinical Isolates Of Human Skin Pathogenic Bacteria And Fungi Faroliu, Goldha; Adriani, Nova; Wulandari, Sarah
JURNAL FARMASI GALENIKA Vol 12 No 3 (2025): Jurnal Farmasi Galenika Volume 12 No 3
Publisher : Universitas Bhakti Kencana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70410/jfg.v12i3.405

Abstract

Betadin leaf (Jatropha multifida L.) is an ornamental plant in Indonesia and is rarely used, but its leaf sap has been reported to accelerate wound healing due to skin infections. This has the potential to be used for the development of new antimicrobial agents. The extraction method was carried out by maceration using 96% ethanol and fractionation with ethyl acetate. Extracts and fractions analyzed for the presence of various phytochemical constituents. Antibacterial assay used disc diffusion (Kirby-Bauer's) method towards Propionibacterium acnes, Staphylococcus epidermidis, Corynebacterium diphtheriae, Microsporum canis and Epidermophyton floccosum. Ethanol extract of Betadin leaves contained Alkaloids, Flavonoids, Phenolics, Steroids, Terpenes, Saponins, while the ethyl acetate fraction contained Alkaloids, Phenolics, Terpenes. J. multifida leaf ethanol extract has strong activity towards Microsporum canis and Epidermophyton floccosum, and has weak activity towards Propionibacterium acnes, Staphylococcus epidermidis, and Corynebacterium diphtheriae. While J. multifida leaf ethyl acetate fraction has strong activity towards Propionibacterium acnes, Microsporum canis and Epidermophyton floccosum, and has weak activity towards Staphylococcus epidermidis, and Corynebacterium diphtheriae. Based on the results of this study can be concluded that both the ethanol extract and the ethyl acetate fraction of Betadin leaves (Jatropha multifida L.) had the ability to inhibit the growth of bacteria and fungi, then can be antimicrobial candidate of herbal medicine
Co-Authors Adriani, Nova Faroliu, Goldha