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All Journal Jurnal Riset Manajemen dan Bisnis Gema Lingkungan Kesehatan
Karim, Muhammad Yusuf
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Decision Sciences, Operations Research & Management Economics, Econometrics & Finance Environmental Science Health Professions Immunology & microbiology Public Health Social Sciences

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The role of education in improving labor productivity in the manufacturing sector. Aulia, Amahda Nur; Rahma, Khoirul Sahita; Ardiansyah, Muhammad Ashroful; Karim, Muhammad Yusuf; Farliana, Nina
Jurnal Riset Manajemen dan Bisnis Vol 10 No 1 (2025)
Publisher : Lembaga Pengembangan Manajemen dan Publikasi Imperium

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Abstract

Education plays a crucial role in enhancing labor productivity, particularly in the manufacturing sector, which requires high levels of skill and workplace efficiency. This research aims to analyze the influence of education on labor productivity through a comprehensive literature review approach. Various national and international literature were systematically studied to understand how the education level contributes to skill improvement, innovation, and labor efficiency. The findings show that workers with higher education levels tend to have a better understanding of technology, can adapt to industrial changes, and contribute more significantly to production efficiency. Studies in Indonesia indicate a positive correlation between education level and labor productivity in the manufacturing sector, with productivity increases of 5-15% for each higher level of education. Additionally, investment in education has proven to have a positive impact on company competitiveness and overall economic growth. This research recommends the need for education policies aligned with industry needs, strengthening link and match programs, and improving vocational curriculum quality to create a competent and adaptive workforce in the Industrial Revolution 4.0 era.
The Effect of TNF-α and FIB-4 Score on Diastolic Dysfunction in Child Pugh C Liver Cirrhosis Karim, Muhammad Yusuf; Pramana, Triyanta Yuli; Sulastomo, Heru; Nurudhin, Arief; Pamungkasari, Eti Poncorini
Gema Lingkungan Kesehatan Vol. 23 No. 4 (2025): Gema Lingkungan Kesehatan
Publisher : Poltekkes Kemenkes Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36568/gelinkes.v23i4.384

Abstract

Liver cirrhosis is a major global health concern, often complicated by cardiac dysfunction such as diastolic heart failure. Tumor necrosis factor-alpha (TNF-α) and FIB-4 score are widely used biomarkers in cirrhotic patients, but their predictive value for cardiac complications remains unclear. To determine the effect of TNF-α and FIB-4 scores on the severity of diastolic dysfunction in patients with Child-Pugh C liver cirrhosis. This analytical cross-sectional study included 40 Child-Pugh C cirrhotic patients. Serum TNF-α levels were measured using ELISA. Diastolic function was evaluated using echocardiography. Ordinal logistic regression was used to analyze the association between TNF-α, FIB-4, and diastolic dysfunction grades. The majority of participants had moderate (65.0%) or severe (35.0%) chronic inflammation based on TNF-α levels, with a median TNF-α of 45.52 pg/mL. Significant liver fibrosis (FIB-4 >3.25) was observed in 82.5% of participants. Grade I diastolic dysfunction was the most prevalent (52.5%). TNF-α levels were significantly associated with the degree of diastolic dysfunction (p=0.042), whereas FIB-4 scores showed no significant correlation (p=0.533). Elevated TNF-α is strongly associated with worsening diastolic dysfunction in Child-Pugh C cirrhosis, suggesting its role in systemic inflammation and myocardial injury. In contrast, the FIB-4 index may not reflect cardiac involvement in advanced cirrhosis. TNF-α may serve as a potential biomarker for cardiovascular risk stratification in cirrhotic patients, supporting early intervention and integrated care approaches.
Co-Authors Ardiansyah, Muhammad Ashroful Arief Nurudhin Aulia, Amahda Nur Eti Poncorini Pamungkasari Nina Farliana Rahma, Khoirul Sahita Sulastomo, Heru Triyanta Yuli Pramana