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All Journal Jurnal Medika Malahayati Journal of Ageing And Family
Parmelia, Manik
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Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Nursing Public Health

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PILIHAN MANAJEMEN PASCA PAJANAN ANTRAKS PADA MANUSIA: KAJIAN LITERATUR Parmelia, Manik; Ardanayasa, I Gede Risnawan Suastika; Kenwa, Komang
Jurnal Medika Malahayati Vol 7, No 4 (2023): Volume 7 Nomor 4
Publisher : Universitas Malahayati

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33024/jmm.v7i4.11285

Abstract

Abstrak: Pilihan untuk Manajemen Pasca Pajanan Antraks pada Manusia: Sebuah Telaah Sistematis. Anthrax adalah penyakit zoonosis yang disebabkan oleh bakteri bacillus anthracis. Manajemen yang cepat dan tepat diperlukan untuk mencegah hasil yang merugikan pada pasien antraks pada manusia. Tulisan ini bertujuan untuk menjelaskan lebih lanjut terapi yang tersedia untuk manajemen pasca paparan antraks. Pencarian PubMed dilakukan untuk ‘human anthrax’ AND ‘treatment’ dari database selama 10 tahun terakhir. Sebanyak 1.449 artikel ditemukan dan 8 studi ditelaah lebih jauh. Delapan penelitian menunjukkan beberapa pilihan post-exposure prophylaxis (PEP) untuk antraks pada manusia, terutama anthrax  inhalasi, yaitu imunoglobulin, raxibacumab, obiltoxaximab, dan beberapa jenis yang masih dalam pengembangan, seperti AV7909 dan Px563L. Telaah sistematis ini menunjukkan bahwa setiap penelitian menunjukkan konsentrasi antraks yang bertahan lama dan dalam jumlah yang tinggi dalam sirkulasi sehingga menunjukkan terapi imunoglobulin dapat berperan sebagai profilaksis pasca pajanan yang baik dengan menunjukkan respons imun yang adekuat pada orang sehat.
A New Challenge in Treatment of Sarcopenic Obesity in Older Adults: A Systematic Review Parmelia, Manik; Sastrawan, I Gede Agus; Kenwa, Komang
Journal of Ageing And Family Vol 3, No 2 (2023): Journal of Ageing And Family
Publisher : Lembaga Penelitian dan Pengabdian Masyarakat (LPPM Universitas Respati Indonesia)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52643/joaf.v3i2.4137

Abstract

Introduction: Sarcopenic obesity (SO) defined as a phenotype of coexistence of sarcopenia, is an age-related loss of muscle mass and strength or physical performance, and obesity. It is crucial to determine the best management strategy for sarcopenic obese patients in order to improve life expectancy. The goal of this review is to provide an overview of sarcopenic obesity treatment for older persons. Methods: PubMed searches were conducted for ‘sarcopenic obesity treatment’ and ‘sarcopenic obesity elderly treatment’ from a database through the past 10 years. All articles available in English identified by these searches were then reviewed in detail Result: At present, the optimal treatment of sarcopenic has not been established. Nutritional interventions, such as a hypocaloric diet, and exercise training or physical therapy are the mainstay of SO prevention and treatment to achieve changes in body composition (muscle gain and fat reduction) and improve the functional status and quality of life of elderly patients. Conclusion: To further our understanding of SO, it is essential that clinicians and researchers establish a universal consensus for the definition and diagnosis of SO and focus on SO treatment and promote healthy aging. Keywords: sarcopenic obesity, elderly, treatment
Co-Authors Ardanayasa, I Gede Risnawan Suastika Kenwa, Komang Sastrawan, I Gede Agus