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Hubungan Resistensi Antibiotik Pada Pasien Sepsis dan COVID-19 : Literatur Review Amir, Nur Rezky Rutami; Sauma, Anis Khoirun; Kurnia Eryani; peppy dwi endraswari
Jurnal Farmasi UIN Alauddin Makassar Vol 12 No 1 (2024): Jurnal Farmasi Edisi Mei
Publisher : Universitas Islam Negeri Alauddin Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24252/jfuinam.v12i1.42468

Abstract

Background: COVID-19 disease with secondary infection especially, and should be treated immediately with exact antibiotics related to the patient's condition to return the patient's hemodynamics. The consumption of antibiotics that are imprecise, and not based on method will cause antibiotic resistance, and it will increase the illness, elevating the complications, and mortality. Objective: This literature research is aimed to explore the relationship between the consumption of antibiotics toward sepsis and COVID-19 patients. Methods: This research applied a literature review method by using primary and secondary data and specifically using the database from article research such as Google Scholar Science Direct, MDPI, Elsevier, NCBI, Springer, Taylor and Francis, Oxford Academic, and Higher Press related on the inclusion. Results: During the data collection session, five articles were analysed specifically for entering the data PICO table (Population, Intervention, Comparison, and Outcome) and concluded each article. The result implies that the condition of patients who have COVID-19 in ICU/HCU is risky to have a secondary infection or co-infection such as sepsis, this condition requires precise antibiotics.Conclusion: The utilization of antibiotics that are used empirically or de-escalated can cause a risk for the application of various antibiotics and cause a risk of resistance. Several research indicate the resistance of antibiotics used by COVID-19 patients and sepsis due to the imprecise and overuse of antibiotics, the existence of co-infection, comorbid and the influence of intensive patient’s environment.
The Efficacy of Pharmacological and Non-Pharmacological Therapy In Thyroid Storm Patients With Cardiovascular Complications : Literature review Amir, Nur Rezky Rutami; Yulistiani, Yulistiani
Malahayati Nursing Journal Vol 7, No 5 (2025): Volume 7 Nomor 5 (2025)
Publisher : Universitas Malahayati Lampung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33024/mnj.v7i5.18694

Abstract

ABSTRACT Tyroid storm is a life-threatening with clinical manifestation of thyrotoxicosis can cause other organ dysfuntion such as cardiovascular disorders. Therefore, eary detection using Burch and Wartofsky Point Scale that treatment can be optimally. The purpose of literature review is examine the treatment used thyroid storm with cardiovascular complications and the effectiveness of therapy achieve eutiroid. The research use a qualitative method with a literature review design. Data collected from article, journal using keywords and based on inclusion criteria been used Google Scholar and Science Direct databases. The results of journal screening is five journal with case report design. Pharmacological treatment use thionamides, beta blockers, corticosteroids, and potassium iodide, The efficacy  of therapy depending on the patients complications. Non-Pharmacological therapy plasmapheresis, is used if the patient  is given pharmacological therapy and does not show a response after 48 hours of administration. The efficacy of plasmapheresis shows improved clinical effect and euthyroid state. Keywords: Thyroid storm, Pharmacological, Non-Pharmacological, Eutiroid