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PENGARUH EKSPERIENTIAL PEMASARAN DAN IKLAN TERHADAP KESADARAN MEREK SERTA DAMPAKNYA KEPADA KEPUTUSAN PEMBELIAN VAPE MEREK TESLA INVALDER PRODUK ENDS Sinaga, Alex Handani; Sampurno, Sampurno; Derriawan, Derriawan
Medika Tadulako: Jurnal Ilmiah Kedokteran Fakultas Kedokteran dan Ilmu Kesehatan Vol 6, No 3 (2019)
Publisher : Medika Tadulako: Jurnal Ilmiah Kedokteran Fakultas Kedokteran dan Ilmu Kesehatan

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

ABSTRACTWith the development of technology, companies engaged in e-cigarettes always change the marketing target of their products including steam products. In terms of marketing targets, according to Prescient & Strategic Intelligence (2018) "The global e-cigarette market that received $ 13,899.9 million in 2017 and estimates the value of CAGR will move by 19.6% during 2018-2023". Based on electronic cigarette users in Indonesia according to the report of the Global Adult Tobacco Survey: Indonesia Trouble (GATS) in the book tobacco use Indonesia (2012) data shows that in adults, the contribution of e-cigarettes in Indonesia in 2011 reached (10.90% ) but only (0.3%) uses the product. The design of this study is a case study with quantitative evaluations carried out by collecting data and information to obtain patterns of consumer relationships with questionnaires, and analyzing statistical data with (SEM Software Amos 19 test), with the aim to test hypotheses that have been provided.  The trend of using Invalder vape tesla in the city of Jakarta about experimental marketing variables on brand awareness = 0.005; advertising variables on brand awareness p = 0.024 and brand awareness variables on purchasing decisions p = 0.00 conversely the marketing experiential variable on purchasing decisions is not significantly significant p = 0.789, and the advertising variable on buying decisions p = 0.237. Based on the value of the Goodness Of Fit criteria, a Chi-square value of 0.060 is obtained, a GFI value of 0.915 from the standard> 0.90, an NFI value of 0.844 from the standard of <0.90 and a TLI value of 0.910, from a standard> 0.90 so that it can be obtained the developed model is acceptable (Fit). Keywords : Experiential Marketing, Advertising, Brand Awareness, and Invalder Vape Tesla Purchasing Decisions ABSTRAK Dengan perkembangan tekhnologi maka perusahaan yang bergerak dibidang e-rokok selalu memperhitungkan target pemasaran produknya termasuk produk vapor. Dari segi target pemasaran, menurut Prescient & Strategic Intelligance (2018), menyatakan “Pasar e-rokok global dihargai $ 13.899,9 juta pada 2017 dan diperkirakan nilai CAGR akan mengalami inflasi sebesar 19,6% selama 2018-2023”. Berdasarkan pengguna rokok elektronik di Indonesia menurut  laporan Global Adult Tobacco Survey: Indonesia Repot (GATS) dalam buku tobacco use Indonesia (2012) data menunjukkan pada orang dewasa proporsi e-rokok yang ada di Indonesia mencapai pada tahun 2011 mencapai (10,90%) namun hanya (0,3%) yang menggunakan produk tersebut. Desain penelitian ini adalah penelitan kasualitas dengan pendekatan secara kuantitatif dilakukan dengan cara pengumpulan data dan informasi untuk memperoleh pola perilaku konsumen berupa kuisioner, dan analisa data bersifat statistika dengan (uji SEM Sofwere Amos 19), dengan tujuan untuk menguji hipotesis yang telah ditetapkan. Tren penggunaan vape tesla Invalder di kota Jakarta secara langsung dipengaruhi oleh variabel eksperiental pemasaran terhadap kesadaran merek = 0.005; variabel iklan terhadap kesadaran merek p= 0,024 dan variabel kesadaran merek terhadap keputusan pembelian p= 0.00 sebaliknya variabel ekperiental pemasaran terhadap keputusan pembelian tidak berpengaruh secara signifikan p = 0,789, dan variabel iklan terhadap keputusan pemebelian p = 0,237. Berdasarkan nilai kriteria Goodness Of Fit  diperoleh nilai Chi square sebesar 0,060, nilai GFI sebesar 0,915 dari standar >0,90, nilai NFI sebesar 0,844 dari standar sebesar < 0,90 dan nilai TLI sebesar 0,910, dari standar > 0,90 sehingga dapat dikatakan bahwa model yang dikembangkan dapat diterima (Fit).Kata kunci : Eksperiental Pemasaran, Iklan, Kesadran Merek dan Keputusan Pembelian Vape tesla Invalder
INTERAKSI OBAT ANTIDIABETES DENGAN OBAT ANTITUBERKULOSIS (OAT) PADA PASIEN DIABETES MELLITUS TIPE 2 YANG TERINFEKSI TB PARU DI INSTALASI RAWAT INAP RUMAH SAKIT UMUM IMELDA PEKERJA INDONESIA MEDAN Auliafendri, Novycha; Sinaga, Alex Handani; Gea, Kiki Restini
JIFI (Jurnal Ilmiah Farmasi Imelda) Vol. 8 No. 1 (2024): JIFI (Jurnal Ilmiah Farmasi Imelda)
Publisher : Universitas Imelda Medan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52943/jifarmasi.v8i1.1716

Abstract

Diabetes is a medical condition that can worsen the severity of pulmonary tuberculosis (TB) infection. Combining Antidiabetic Drugs with Antituberculosis Drugs (OAT) in type 2 DM patients who have pulmonary TB can cause undesirable pharmacological interactions. The aim of this study is to explain the relationship between Antidiabetic Drugs and OAT. The research design used in this study is a cross-sectional observational design, with a focus on descriptive statistical analysis. The research sample consisted of 72 patients. Data collection was carried out retrospectively using medical records and doctor's prescription forms. The Medscape (Drug Interactions Checker) tool was used for drug interaction analysis, while SPSS (Statistical Product and Service Solution) 21.0 for Windows was used for data processing. Research findings revealed that the occurrence of drug interactions between Antidiabetic Drugs and OAT varied based on gender characteristics, with 56.9% observed in men and 43.1% in women. Pharmacodynamic interactions reached 25.5% based on the mechanism of action, while pharmacokinetic interactions reached 5.7%. The remaining 68.9% were classified as unknown interactions. In contrast, minor types of drug interactions reached 68.9% in terms of severity, while moderate types of interactions reached 31.1%, and there were no significant interactions. This study concludes that the combination of antidiabetic drugs and OAT mainly causes pharmacological interactions both in the pharmacodynamic and pharmacokinetic pathways, with varying levels of severity, ranging from minimal to moderate.
Addition Of Various Concentrations Of Gadung Tuber Starch Which Is Determined As A Binder To The Physical Properties Of Mefanamic Acid Tablets By Wet Granulation Sinaga, Alex Handani; Fendri , Novicha Aulya
Jurnal Kesehatan, Rekam Medis dan Farmasi (JUK-Medifa) Vol. 2 No. 01 (2023): JUK-Medifa (Jurnal Kesehatan, Rekam Medis dan Farmasi), November 2023
Publisher : SEAN Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58471/juk-medifa.v2i01.234

Abstract

n previous studies, the polysaccharide extract of gadung tuber has a hypoglycemic effect, wherein the plant contains a high glycemic index indicating that carbohydrates undergo rapid digestion and are absorbed in large quantities so that blood glucose levels suddenly experience a rapid rise in insulin which can lower cholesterol values. (Sumunar et al., 2015) This research method is an experiment in which this research was carried out, by making starch from gadung starch and making tablets by wet granulation. Based on the results of the research that has been done, it can be concluded that the use of gadung starch as a binder can produce mefanamic acid tablets that meet the requirements for uniformity of tablet weight, tablet hardness, tablet friability, and tablet disintegration time in the Indonesian Pharmacopoeia. The addition of gadung starch (Discorea Hispida Dennst.) as a binder to mefanamic acid tablets causes differences in the physical properties of the tablets, namely in greater tablet hardness, smaller tablet friability and longer tablet disintegration time. The significance value obtained was 0.00 <0.05, because there was a significant difference in the gadung formulation and the gadung formulation as a binder for mefanamic acid tablets
Analisis Polimorfisme Genetik sebagai Prediktor Respons Imun dan Efektivitas Terapi Standar pada Pasien Diabetes Melitus Tipe 2 Novycha Auliafendri; Sinaga, Alex Handani
INSOLOGI: Jurnal Sains dan Teknologi Vol. 4 No. 5 (2025): Oktober 2025
Publisher : Yayasan Literasi Sains Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55123/insologi.v4i5.6488

Abstract

Type 2 diabetes mellitus (T2DM) is a chronic disease with high prevalence and significant public health impact. This study aimed to analyze the association of IL-6 gene polymorphism (−174G>C) with serum IL-6 levels and the effectiveness of standard therapy assessed through HbA1c and Random Blood Glucose (RBG) in T2DM patients. A cross-sectional design was employed, involving 40 patients at Imelda Hospital. The polymorphism was examined using Polymerase Chain Reaction (PCR), serum IL-6 levels were measured with Enzyme-Linked Immunosorbent Assay (ELISA), while HbA1c and RBG were determined through standard laboratory analysis. The results indicated that IL-6 genotypes (GG, GC, CC) were not significantly associated with serum IL-6 levels, HbA1c, or RBG. In contrast, type of therapy showed a significant relationship with HbA1c, where patients receiving combination therapy achieved better glycemic control compared to those on monotherapy. These findings highlight that therapeutic regimen remains the primary determinant of glycemic control, whereas the role of IL-6 polymorphism in this study population appears limited. Further studies with larger sample sizes and broader genetic analyses are required to strengthen the application of precision medicine for diabetes management in Indonesia.
EVALUASI INTERAKSI OBAT ANTIRETROVIRAL PASIEN HIV-AIDS RAWAT INAP DI RUMAH SAKIT UMUM IMELDA PEKERJA INDONESIA MEDAN Auliafendri, Novycha; Sinaga, Alex Handani; Hasibuan, Nabila Nazwa
JIFI (Jurnal Ilmiah Farmasi Imelda) Vol. 8 No. 2 (2025): JIFI (Jurnal Ilmiah Farmasi Imelda)
Publisher : Universitas Imelda Medan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52943/jifarmasi.v8i2.1830

Abstract

HIV/AIDS merupakan masalah kesehatan global dengan tingkat kematian yang tinggi, meskipun terapi antiretroviral (ARV) terbukti efektif dalam menghambat perkembangan virus. Namun, interaksi antara obat ARV dan obat lain yang diberikan sering kali mempengaruhi efektivitas terapi serta meningkatkan risiko efek samping. Oleh karena itu, evaluasi interaksi obat ARV menjadi penting untuk memastikan keamanan dan efektivitas terapi. Penelitian ini bertujuan untuk melibatkan interaksi obat antiretroviral secara farmasetik, farmakokinetik, dan farmakodinamik pada pasien rawat inap dengan HIV/AIDS di RSU IPI Medan. Penelitian ini menggunakan metode observasional retrospektif dengan mengumpulkan data dari rekam medis pasien HIV/AIDS yang dirawat di RSU IPI Medan pada periode Januari–Desember 2023. Data yang dianalisis meliputi karakteristik pasien, jenis obat ARV yang digunakan, serta potensi interaksi obat berdasarkan mekanisme farmakokinetik dan farmakodinamik. Dari penelitian menunjukkan bahwa kombinasi obat antiretroviral yang paling banyak digunakan adalah tenofovir (TDF), lamivudin (3TC), dan dolutegravir (DTG), yang digunakan oleh 40 pasien (57%). Dari total tersebut, terdapat 82 kasus interaksi obat (97,6%), dengan tingkat keparahan interaksi sedang sebanyak 69%, mayor 24%, dan minor 7%. Interaksi dengan mekanisme farmakokinetik mencapai 68%, farmakodinamik sebesar 32% dan interaksi secara farmasetik tidak ada. Penelitian ini menekankan perlunya pemantauan yang lebih ketat dan kolaborasi antar tenaga kesehatan untuk meminimalkan risiko interaksi obat dalam pengobatan pasien HIV/AIDS