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PENGARUH PENYULUHAN TERHADAPPENGETAHUAN DAN PERILAKU MASYARAKAT MENGENAI ANTIBIOTIKA DI KELURAHAN SRENGSENG SAWAH JAGAKARSA JAKARTA SELATAN Silvi Nurafni; Syamsudin; Sesilia A. Keban
Jurnal Farmamedika (Pharmamedika Journal) Vol 4 No 2 (2019): Jurnal Farmamedika (Pharmamedica Journal)
Publisher : Sekolah Tinggi Teknologi Industri dan Farmasi Bogor

Penyuluhan tentang antibiotika merupakan salah satu cara yang digunakan untuk menambah pengetahuan tentang antibiotika dengan tujuan mengubah perilaku dalam penggunaan antibiotika. Penelitian ini bertujuan untuk mengukur pengetahuandan perilaku masyarakat sebelum dan sesudah penyuluhan, dan merupakan penelitian Quasi-Experimental Nonrandomized Control Group Pretest Postest Design. Pengambilan sampel secara acak dengan teknik Cluster sampling pada Kader PKK di Kelurahan Srengseng Sawah Jagakarsa Jakarta Selatan. Pada kelompok perlakuan berjumlah 106 orang diberikan penyuluhan tentang antibiotika, sedangkan pada kelompok kontrol berjumlah 111 orang tidak diberikan penyuluhan. Gambaranpengetahuandan perilakudianalisismenggunakan ujidistribusiFrekuensi, perbedaanantarakelompokperlakuan dan kontroldigunakan uji Independent Sample T-test, perbedaan sebelum dan setelah penyuluhan digunakan uji paired T-test, pengaruh penyuluhan terhadap tingkat pengetahuan, dan perilaku digunakan uji Regresi Linear. Hasil penelitian menunjukkan gambaran pengetahuan, perilaku responden sebelum dilakukan penyuluhan antara kelompok perlakuan dan kontrol tidak berbeda bermakna. Namun, setelah dilakukan penyuluhan terjadi peningkatan persentase responden yang menjawab dengan tepat pada kelompok perlakuan. Setelah penyuluhan terjadi perbedaan bermakna pada pengetahuan dan perilaku antara kelompok perlakuan dan kontrol (P<0,001). Peningkatan nilai pengetahuan sebesar 47,2% pada kelompok perlakuan dan 1,4% pada kontrol, perilaku sebesar 29,5% pada kelompok perlakuan dan 0,7% pada kontrol. Hasil analisis regresi linier menunjukkan pengetahuan dan usia mempunyai pengaruh yang erat dengan perubahan perilaku (p<0,05). Sehingga disimpulkan semakin tinggi tingkat pengetahuan responden maka perilaku semakin baik. Namun, semakin tua usia responden perilaku semakin buruk.

UJI AKTIVITAS OBAT HERBAL GEL EKSTRAK DAUN GAHARU (Gyrinops versteegii (Gilg.) Domke) TERHADAP LUKA DIABETES PADA TIKUS PUTIH JANTAN (Rattus norvegicus) Silvi Nurafni; Antonius Padua Ratu; Tia Marliana; Ega Rahmawati
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 7 No 2 (2022): JIIS
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jiis.v7i2.1002

A study to test the activity of gel extract of gaharu (Gyrinops versteegii (Gilg.) Domke) leaf extract against diabetic wounds in male white rats (Rattus norvegicus). The research was conducted experimentally with the method of pre-test and post-test with group design. Gaharu leaf extract gel was formulated with concentrations of 4%, 6% and 8% and then tested for its activity on non-diabetic male white rats and diabetic male rats with alloxan induction. The negative control was given gel base and the positive control was given bioplacenton gel. The gel was administered once a day and the wound length was measured every day for 14 days. The results showed that all gel formulas of gaharu leaf extract had wound healing activity in non-diabetic rats and diabetic rats, the higher the concentration of the extract, the faster the wound healing and the greater the percentage reduction in wound length. The group of non-diabetic rats treated with gaharu extract gel with a concentration of 8% showed a wound length of 0,00 Â± 0,00 mm (wound healed) on day 6 with an average percentage reduction in wound length of 100,00 Â± 0,00 %. The results of statistical testing with Kruskal Wallis obtained p-value > 0.05 (p-value = 0.315) so it can be concluded that there was no significant difference between the treatment groups.

UJI AKTIVITAS OBAT HERBAL GEL EKSTRAK DAUN GAHARU (Gyrinops versteegii (Gilg.) Domke) TERHADAP LUKA DIABETES PADA TIKUS PUTIH JANTAN (Rattus norvegicus) Silvi Nurafni; Antonius Padua Ratu; Tia Marliana; Ega Rahmawati
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 7 No 2 (2022): JIIS
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jiis.v7i2.1002

A study to test the activity of gel extract of gaharu (Gyrinops versteegii (Gilg.) Domke) leaf extract against diabetic wounds in male white rats (Rattus norvegicus). The research was conducted experimentally with the method of pre-test and post-test with group design. Gaharu leaf extract gel was formulated with concentrations of 4%, 6% and 8% and then tested for its activity on non-diabetic male white rats and diabetic male rats with alloxan induction. The negative control was given gel base and the positive control was given bioplacenton gel. The gel was administered once a day and the wound length was measured every day for 14 days. The results showed that all gel formulas of gaharu leaf extract had wound healing activity in non-diabetic rats and diabetic rats, the higher the concentration of the extract, the faster the wound healing and the greater the percentage reduction in wound length. The group of non-diabetic rats treated with gaharu extract gel with a concentration of 8% showed a wound length of 0,00 ± 0,00 mm (wound healed) on day 6 with an average percentage reduction in wound length of 100,00 ± 0,00 %. The results of statistical testing with Kruskal Wallis obtained p-value > 0.05 (p-value = 0.315) so it can be concluded that there was no significant difference between the treatment groups.

Hubungan Frekuensi Pemberian ERYTHROPOIETIN STIMULATING AGENT (ESA) Dengan Peningkatan Hemoglobin Pasien Hemodialisa Di RSUD Ciawi Nurafni, Silvi; Desminingrum, Tri; Samsiah, Siti
Jurnal Farmasi & Sains Indonesia Vol 6 No 1 (2023)
Publisher : LPPM Sekolah Tinggi Ilmu Farmasi Nusaputera

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52216/jfsi.vol6no1p17-24

Anemia complicated by CKD occurs 80-90% due to deficiency of erythropoietin. Erythropoietin Stimulating Agent (ESA) therapy is the main choice at Ciawi Hospital. Chronic Kidney Failure (CKD) is the 7th 10th biggest disease in Ciawi Hospital. The aim of the study was to evaluate the success of Erythropoietin Stimulating Agent (ESA) treatment in Hemodialysis (HD) patients at Ciawi General Hospital. This research is descriptive in nature, collecting retrospective data from secondary data from medical records, laboratory data from Hb patients. Sampling was taken using the total sampling method, namely all outpatient Hemodialysis (HD) patients at the Ciawi Hospital for the period October-December 2021 who met the inclusion and exclusion criteria totaling 47 patients. The results of this study show the sociodemographic picture of patients with Chronic Kidney Failure (CKD) with anemia complications, the most age range being 46-55 years, 18 patients (38.30%), the most sex being male, 25 patients (53.19%). The description of the duration of Hemodialysis (HD) therapy is that the most ? 12 months 27 patients (57.45%). The description of the highest frequency of ESA administration was at a frequency of 2 times a month with the Hb category increasing by 21 patients (63.6%) and the Hb category decreasing by 12 patients (36.4%). There is no relationship between the frequency of Erythropoietin Stimulating Agent (ESA) therapy with an increase in hemoglobin values in patients with chronic kidney failure undergoing hemodialysis and suffering from anemia as indicated by a significance value (P-value) of 0.659 > 0.05.

GAMBARAN KESESUAIAN DOSIS TERAPI CAIRAN, HEMATOKRIT, TROMBOSIT, LAMA RAWAT PASIEN DBD ANAK DI RUMAH SAKIT ISLAM BOGOR Paloma, Yacinta; Nurafni, Silvi; Fawwaz, Kahlaa Nabiilah
SOCIAL CLINICAL PHARMACY INDONESIA JOURNAL Vol 10, No 1 (2025)
Publisher : Universitas 17 Agustus 1945 Jakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52447/scpij.v10i1.8610

Demam berdarah dengue (DBD) merupakan salah satu penyakit menular yang ditularkan oleh gigitan nyamuk Aedes aegypti yang banyak menyerang anak-anak. Prinsip utama pengobatan DBD adalah terapi suportif dan pemeliharaan volume cairan sirkulasi. Seseorang yang terinfeksi DBD dapat ditandai dengan adanya kebocoran plasma seperti peningkatan hematokrit dan penurunan jumlah trombosit. Penelitian ini bertujuan untuk mengetahui gambaran kesesuaian dosis terapi cairan, hematokrit, trombosit dan lama rawat pasien DBD pada anak yang dirawat di Rumah Sakit Islam Bogor. Metode yang digunakan dalam penelitian ini yaitu metode analitik observasional, dengan rancangan penelitian cross sectional. Data diambil dari rekam medik pasien selama bulan Januari-Desember 2024 dengan sampel sebanyak 59 pasien. Hasil penelitian menunjukkan bahwa dari 59 pasien, sebanyak 54,20% pasien menjalani terapi cairan dengan dosis sesuai dengan nilai hematokrit terbanyak yaitu 33-38%, nilai trombosit terbanyak yaitu 50.000-100.000 sel/μL dan lama rawat terbanyak yaitu ≤ 4 hari. Kesimpulan yang diperoleh dari penelitian ini adalah sebanyak 54,20% pasien DBD pada anak di RS Islam Bogor periode Januari-Desember 2024 mendapatkan dosis terapi cairan yang sesuai dengan pedoman tatalaksana DBD menurut Kemenkes tahun 2021, memiliki nilai hematokrit yang sesuai sebanyak 40,7%, trombosit yang sesuai sebanyak 33,8% dan lama rawat ≤ 4 hari sebanyak 32,2%.Kata kunci: DBD, Hematokrit, Lama Rawat, Terapi Cairan, Trombosit.

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