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PERBANDINGAN LATIHAN KONTINU INTENSITAS SEDANG DAN LATIHAN INTERVAL INTENSITAS TINGGI TERHADAP KONTROL GLUKOSA DARAH Argarini, Raden; Atsari, Nadhila; Susanto, Hermawan
Majalah Kedokteran Bandung Vol 48, No 4 (2016)
Publisher : Faculty of Medicine, Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (297.808 KB) | DOI: 10.15395/mkb.v48n4.909

Abstract

Pencegahan diabetes melitus tipe 2 (DMT2) dapat dilakukan dengan memperbanyak latihan fisik. Latihan kontinu intensitas sedang (LKIS) dan latihan interval intensitas tinggi (LIIT) diketahui dapat meningkatkan kontrol glukosa pada orang dengan resistensi insulin/DMT2. Tujuan penelitian ini adalah membandingkan efek LIIT dan LKIS pada orang sehat terhadap kontrol glukosa darah, yaitu glukosa darah puasa (GDP) dan tes toleransi glukosa oral (TTGO). Laki-laki (n=27), usia (20,07±0,62), IMT (23,94±3,59) kg/m2 berpartisipasi dalam kelompok LKIS, LIIT, atau kontrol. Latihan Ergocycle dilakukan 3 sesi/minggu selama 4 minggu; LKIS dengan total durasi 46 menit/sesi (intensitas sedang 50-60% denyut jantung cadangan [HRR] selama 40 menit); LIIT dengan total durasi 24 menit/sesi (6 siklus; 2 menit intensitas tinggi 80?90% HRR + 1 menit intensitas sedang 50?60% HRR). Kontrol tidak mendapat intervensi latihan. GDP dan TTGO (120? setelah beban glukosa) diperiksa 3 hari sebelum dan setelah program latihan. Hasil penelitian menunjukkan GDP menurun pada semua kelompok, tetapi hanya LKIS yang menunjukkan penurunan signifikan (p=0,048). TTGO ditemukan tidak berubah di semua kelompok (p>0,05). LKIS memiliki potensi untuk meningkatkan kontrol glukosa darah pada subjek dewasa muda. Penelitian lanjutan dengan modifikasi dosis latihan diperlukan untuk mengetahui efek LIIT lebih lanjut. [MKB. 2016;48(4):194?9]Kata kunci: kontrol glukosa darah, latihan interval intensitas tinggi, latihan kontinu intensitas sedangComparison of Moderate Intensity Continuous Training and High Intensity Interval Training on Blood Glucose ControlAbstractType 2 diabetes mellitus (T2DM) can be prevented by intensive physical exercise/training. Moderate intensity continuous training (MICT) and high intensity interval training (HIIT) are known to improve glucose control in people with insulin resistance and T2DM. The purpose of this study was to compare the effects of MICT and HIIT in healthy people on blood glucose levels, which was measured through fasting blood glucose (FBG) and oral glucose tolerance test (OGTT). Healthy men (n=27), aged (20.07 ± 0.62), BMI (23.94 ± 3.59) kg/m2 participated in either MICT, HIIT, or Control group (n=9 each group). Ergocycle exercise were performed 3 times/week for 4 weeks; MICT with a total duration of 46 minutes/session (moderate intensity 50-60% heart rate reserve [HRR]) for 40 minutes); HIIT with a total duration of 24 minutes/session (6 cycles; 2 mins high intensity 80-90% HRR + 1 min moderate intensity 50-60% HRR). Controls did not receive any programmed training. FBG and OGTT (120? after glucose load) were checked 3 days before and after the exercise program. This study found that FBG decreased in all groups but only the MICT group showed a significant reduction (p=0.048). OGTT was found unaltered in all groups (p>0.05). MICT has the potential to improve blood glucose control in healthy young adult subjects. However, further research with exercise dose modification is required to elucidate the effects of HIIT. [MKB. 2016;48(4):194?9]Key words: Blood glucose control, high intensity interval training, moderate intensity continuous training
Acute Fatty Liver of Pregnancy Management in Intensive Care Atsari, Nadhila; Apsari, Ratih Kumala Fajar; Adiyanto, Bowo; Widodo, Untung
Solo Journal of Anesthesi, Pain and Critical Care (SOJA) Vol 6, No 1 (2026): April 2026
Publisher : Fakultas Kedokteran Universitas Sebelas Maret Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20961/soja.v6i1.78517

Abstract

Background: Acute fatty liver of pregnancy (AFLP) is an obstetric emergency with high mortality that usually requires treatment in the intensive care unit (ICU). The cause of AFLP is not known with certainty, but it is suspected due to a deficiency of long chain 3-hydroxyacyl CoA dehydrogenase (LCHAD) in the fetus which causes accumulation of fatty acid metabolites from the fetus and placenta which are hepatotoxic. The clinical manifestations of AFLP are acute liver failure and progression to multiple organ dysfunction syndrome (MODS). This reported case was the only one successful case out of 3 incidences of AFLP recorded in RSUP Dr. Sardjito Yogykarta within a year of 2022. Case Illustration: A 24-years-old postpartum woman at 38 weeks' gestation admitted to resuscitation room with hypovolemic shock due to early postpartum hemorrhage. Patient was resuscitated and then taken to emergency operating room for uterine exploration under general anesthesia. Patient was subsequently admitted to the intensive care unit (ICU).  The patient's initial condition was intubated, requiring vasopressor support with epinephrine and norepinephrine, and the patient showed symptoms of encephalopathy, liver failure and kidney failure. AFLP diagnosis was then made with patient showing score 10 of Swansea criteria. Resuscitation, stabilization, and intensive care treatment was continued for up to eight days in the ICU. The patient's final condition was stable, there were no sequelae of AFLP and the patient was discharged from the hospital at the 14th day in good condition.Conclusion: AFLP is a serious complication during pregnancy and postpartum period that is reversible with a chance of complete recovery but has a high mortality associated with delayed treatment. Adequate early intensive care treatment with multidisciplinary approach essential for successful treatment of AFLP.