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All Journal JIMKesmas (Jurnal Ilmiah Mahasiswa Kesehatan Masyarakat) Healthy Tadulako Journal (Jurnal Kesehatan Tadulako)
Annisa, Elvia
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Dentistry Health Professions Medicine & Pharmacology Nursing Public Health

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UJI EFEKTIVITAS EKSTRAK METHANOL DAUN BANGUN-BANGUN (COLEOUS AMBOINICUS) TERHADAP JAMUR CANDIDA ALBICAN Diana S, M Putri; Annisa, Elvia; Mutia, Maya Sari
(Jurnal Ilmiah Mahasiswa Kesehatan Masyarakat) Vol 5, No 1 (2020): JIMKesmas (Jurnal Ilmiah Mahasiswa Kesehatan Masyarakat)
Publisher : Universitas Halu Oleo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37887/jimkesmas.v5i1.10747

Abstract

Abstrak : Infeksi jamur Candida albican adalah pathogen yang sering dijumpai dan menginfeksi pada lingkungan sekitar karenajamur ini bersifat flora normal pada tubuh. Daun bangun-bangun (Coleus amboinicus) adalah tanaman yang sangatdikenal pada rakyat suku batak dengan memiliki kandungan flavoniod dan tannin. Pada penelitian ini bertujuan untukmengetahui pengaruh daun bangun-bangun(Coleus amboinicus)terhadap pertumbuhan jamur Candida albicansdengan metode cakram pada suatu kelompok control, yaitu dilakukan dengan konsentrasi 20%,40%,60%,80%,dan100%. Pada hasil akhir penelitian menunjukkan zona hambat di ekstrak daun bangun-bangun (Coleus amboinicus)dengan konsentasi 20%,40%,60%,80%,dan 100%. Zona hambat yang ditemukan adalah memilki rata-rata diameter14,21, 16,05, 16,65, 17,61, dan 18,23. Kesimpulan yang didapat pada rata-rata zona hambat menunjukkan perbedaanhasil setiap perlakuan konsentrasi, semakin besar konsentrasi ekstrak daun bangun-bangun maka semakin besarzona hambat pada Candida albican. Kata kunci : Ekstrak daun bangun-bangun (Colous amboinicus), Candida albican
ANTI-BACTERIAL ACTIVITY OF ETHANOL EXTRACT OF INDIAN BORAGE (Coleus Amboinicus) LEAVES AGAINST BACILLUS CEREUS Mutia, Maya Sari; Annisa, Elvia; Suhartomi, Suhartomi
Healthy Tadulako Journal (Jurnal Kesehatan Tadulako) Vol. 7 No. 1 (2021)
Publisher : Universitas Tadulako

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (331.588 KB) | DOI: 10.22487/htj.v7i1.151

Abstract

Bacillus cereus is aerobic, positive gram, and spore-forming bacilli bacteria. The enterotoxin of this bacteria can cause food poisonous that manifest as diarrhea and vomitus. Some previous study has been performed to explore the antibacterial effect of Indian borage leaf, but none of them were explore the antibacterial effect of Indian borage against Bacillus cereus. Hence this study was design to explore the antibacterial activity of ethanol extract of Indian borage against Bacillus cereus. This was an experimental study with post only control group design. Ethanol extract was extracted by maceration methods and antibacterial activity against Bacillus cereus was evaluated by disc diffusion methods. The obtained ethanol extract was dissolved into some concentraions (1 g/ml, 0.8 g/ml, 0.6 g/ml, 0.4 g/ml, 0.2 g/ml). Data was analysed by One Way ANOVA and followed by Post hoc Test Tukey HSD using SPSS 25. Ethanol extract of Coleus amboinicus showed significant difference at the two highest concentration group against the lowest concentration (P- Value < 0.05). The average of inhibition zone diameter from the lowest (0.2 gr/ml) and highest (1.0 gr/ml) concentration were 14.87 mm and 31.50 mm, respectively. Overall, ethanol extract of Indian borage leaves had potential antibacterial activity against Bacillus cereus. This antibacterial activity increase followed by the increase of the concentration.
Co-Authors Diana S, M Putri Mutia, Maya Sari SUHARTOMI .