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All Journal Media Farmasi : Jurnal Ilmu Farmasi (Journal Of Pharmaceutical Science) Mutiara Medika: Jurnal Kedokteran dan Kesehatan
Kurniawan, Nurcholid Umam
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Chemistry Health Professions Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology

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Life Quality of Pediatric Patient with Dengue Hemorrhagic Fever (DHF) Who Received Crystalloid and Colloid Fluid Treatment in PKU Muhammadiyah Hospital Yogyakarta Nasriyah, Chotijatun; Perwitasari, Dyah Aryani; Kurniawan, Nurcholid Umam
Mutiara Medika: Jurnal Kedokteran dan Kesehatan Vol 19, No 2: July 2019
Publisher : Universitas Muhammadiyah Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18196/mm.190229

Abstract

Dengue hemorrhagic fever (DHF) in the community can have an impact of panic, death, and reduced age of hope in the family. Research on the quality of life of DHF pediatric patient who got the treatment of crystalloid and colloid fluids has never been done before. The purpose of this study was to determine the quality of life of DHF pediatric patients who received crystalloids and colloids with PedsQL instruments. The study design was a cohort with block randomization. The inclusion criteria in this study were hospitalized DHF pediatric patients aged one month -18 years from February to May 2018. The exclusion criteria were DHF patients who came with referrals from other hospitals who had received fluid therapy. Research data include the length of stay (LOS) and quality of life score with the PedsQL questionnaire. The statistical analysis was using an independent t-test and the Mann Whitney test. The length of stay for the crystalloid group is five days longer than the colloid group, which is four days. From a total of 48 subjects studied, the score for the physical function of the crystalloid fluid group 84.54 ± 9.90 was higher than the colloid group of 77.58 ± 19.30 (p = 0.125). The emotional functions in the crystalloid group obtained a score of 81.88 ± 12.14 higher than the colloid group, i.e., 79.17 ± 18.5 (p = 0.552). The social function in the crystalloid group had a score of 92.08 ± 8.84 higher than the colloid group of 86.67 ± 13.96 (p = 0.232). The school functions in the crystalloid group had a score of 50.42 ± 33.68 higher than in the colloid group of 37.92 ± 36.62 (p = 0.225). The results of this study showed that the crystalloid group had a higher quality of life score compared to the colloid group, although it was not significant. 
PENGARUH PEMBERIAN EKSTRAK DAUN JAMBU BIJI (Psidium guajava L) TERHADAP GAMBARAN KLINIS DAN LAMA RAWAT INAP PADA PASIEN ANAK DENGAN DEMAM BERDARAH Akrom, Akrom; Kurniawan, Nurcholid Umam; Ridho, Ery Al
Media Farmasi: Jurnal Ilmu Farmasi Vol. 16 No. 2: September 2019
Publisher : Universitas Ahmad Dahlan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.12928/mf.v16i2.13500

Abstract

Demam berdarah dengue (DBD) merupakan penyakit yang disebabkan virus dengue dan sampai saat ini belum ada pengobatan kuratif untuk mengatasi kebocoran plasma. Penelitian sebelumnya melaporkan daun jambu biji berfungsi sebagai penambah trombosit namun pengujian klinis ekstraknya sebagai antidengue masih sangat terbatas. Penelitian ini bertujuan untuk mengetahui pengaruh pemberian ekstrak daun jambu biji (Psidium guajava L) terhadap perbaikan klinis, laboratoris dan lama rawat inap pada pasien DBD di bangsal anak RS PKU Muhammadiyah Bantul Yogyakarta. Design penelitian adalah eksperimental (RCT) dengan penyamaran single blind. Terdapat 2 kelompok yaitu kelompok intervensi yang mendapatkan terapi standar dan ekstrak daun jambu biji dan kelompok kontrol yang mendapatkan terapi cairan standar WHO. Variable yang diukur adalah suhu badan, trombosit, hematokrit dan lama rawat inap. Analisis data menggunakan program SPSS. Hasil penelitian menunjukkan tidak terdapat perbedaan signifikan antar kelompok terhadap jumlah rerata trombosit pada demam hari ke 1 sampai 10 (p>0,05). Pada parameter hematokrit dan lama rawat inap tidak ditemukan perbedaan yang signifikan antar kelompok dimana nilai p lebih besar dari 0,05 (p>0,05). Pada parameter suhu badan juga tidak terdapat perbedaan sgnifikan (p>0,05). Tidak terdapat perbedaan bermakna antara kelompok intervensi dan kontrol pada parameter laboratorium,klinis maupun lama rawat inap.
Co-Authors Dyah Aryani Perwitasari Endang Darmawan Kusumawati, Leny Witaning Nasriyah, Chotijatun Ridho, Ery Al