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Hubungan Penggunaan Antiretroviral (ARV) dengan Luaran Neonatal pada Ibu Terinfeksi Human Immunodeficiency Virus (HIV) Ariyani, Noor Aida; Radam, M. Robyanoor Ahyadi; Tobing, Samuel L.; Aditya, Renny; Yunanto, Ari; Andayani, Pudji
Indonesian Journal of Obstetrics & Gynecology Science Volume 3 Nomor 1 Maret 2020
Publisher : Dep/SMF Obstetri & Ginekologi Fakultas Kedokteran Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (1613.138 KB) | DOI: 10.24198/obgynia.v3i1.172

Abstract

Tujuan: Mengetahui hubungan penggunaan antiretroviral pada ibu terinfeksi HIV dengan luaran neonatal. Metode: Menggunakan metode analitik dengan pendekatan cross sectional. Pengambilan data dilakukan dari Poli Klinik VCT dan register VK RSUD Ulin Banjarmasin. Jumlah data dibagi berdasarkan penggunaan antiretroviral dan bukan pengguna antiretroviral di hubungkan dengan hasil luaran neonatal berupa berat badan lahir, prematur, IUGR, asfiksia dan kematian neonatal. Analisis menggunakan uji statistik chi square test bermakna bila p < 0.05 ,bila uji chi square tidak memenuhi kriteria maka dilakukan uji fisher.Hasil: Terdapat 73 kasus melahirkan terinfeksi HIV tahun 2015-2018. Ibu terinfeksi HIV yang menggunakan antiretroviral sebanyak 24 (33%) dan bukan menggunakan antiretroviral sebanyak 49 (67%). Dihubungan penggunaan antiretroviral dengan luaran neonatal berat badan lahir bayi, hasil uji square  <0.05 signifikan yaitu  p 0.019,  hasil luaran neonatal prematur (p = 0.022). Hubungan penggunaan antiretroviral terhadap hasil luaran berupa IUGR, asfiksia dan kematian neonatal didapatakan  p 0.166 ; 0.243 ; 0.649.Kesimpulan: Penggunaan antiretroviral pada ibu hamil terinfeksi HIV mengurangi kejadian bayi berat lahir rendah dan prematurRelationship between Antiretroviral Therapy (ARV) with Neonatal Outcome in Woman with HIV InfectionAbstractObjective: Assess the correlation of antiretroviral medication in HIV-infected pregnant women to the outcome of neonates. Method: Analytical method with a cross-sectional approach was used. Data were obtained from the VCT polyclinic and the register of the VK register of Ulin Banjarmasin Regional General Hospital (RSUD). The data are divided into antiretroviral user and non-antiretroviral users linked with the outcome of the neonate in birth weight, prematurity, IUGR, asphyxia, and neonatal death. Statistical analysis using the chi-square test will suggest a significant difference if the p-value is < 0.05. If the chi-square test can not be used, fisher test will be conducted.Result: There are 73 cases of HIV-infected births between 2015 and 2018. There are 24 (33%) of HIV-infected pregnant women on antiretrovirals compared to 49 (67%) non-users. There is a link between antiretroviral usage with the neonatal outcome of birth weight with a chi-square p-value of 0.019 (significant if p-value < 0.05). The outcome of prematurity is also significant, with a p-value of 0.022. The correlation of antiretroviral use to outcome in IUGR, asphyxia, and neonatal mortality are of p-value 0.166; 0.243, and 0.649, respectively.Conclusion: Antiretroviral use in HIV-infected pregnant women reduces the outcome of low birth weight and prematurity incidence in neonates.Key words: HIV, infected woman, outcome, antiretroviral, RSUD Ulin
Exploring the Link Between Severe Preeclampsia and Asymptomatic Urinary Tract Infections in the Third Trimester: A Cross-Sectional Study Abimanyu, Bambang; Budinurdjaja, Pribakti; Radam, M. Robyanoor Ahyadi; Putri, Ruth Widhiati Raharjo; Sauqi, Hardyan; Sabaruddin, Hermin; Vamela, Agatha
Berkala Kedokteran Vol 21, No 2 (2025)
Publisher : Fakultas Kedokteran Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/jbk.v21i2.25138

Abstract

Urinary tract infection (UTI) is prevalent in women between 16 and 35 years old. UTI occurs in 2%-7% of pregnant women and affects the inflammatory process, which damages the vascular endothelium by decreasing nitric oxide (NO). This condition is evident in pregnant women with preeclampsia. This research aims to determine the relationship between urinary tract infections and preeclampsia in the third trimester of pregnancy in the delivery room at Ulin Regional Hospital Banjarmasin from January to December 2023. This study's design was cross-sectional observational using secondary data, including patient registers and medical record data. The sample included those who came in with labor, not labor and post-partum conditions for any causes and third-trimester pregnant patients diagnosed with UTI and Severe Preeclampsia in the delivery room of Ulin Regional Hospital, Banjarmasin and use chi-square test for each category. The 119 total pregnant patients with UTI in the third trimester arriving in the delivery room, 73 of them were diagnosed with preeclampsia. Most of them were under 35 yo. A total of 48 patients had multigravida status in all cases of UTI in preeclampsia in the third trimester of pregnancy. The chi-square analysis of the relationship and preeclampsia in pregnant women in the third trimester with p-value of 0.000, and the Odds ratio value was 4.4. Third-trimester pregnant women who suffer from urinary tract infections are 4.4 times more likely to experience preeclampsia.