Garuda - Garba Rujukan Digital

Exclusive Breastfeeding And Acute Diarrhea In Children: A Cross-Sectional Study Lukman, Leni; Suryawan, I Wayan Bikin
Medicinus Vol 8, No 2 (2019): February : 2019
Publisher : Fakultas Kedokteran Universitas Pelita Harapan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19166/med.v7i4.2383

Introduction : Breastmilk is known to contain molecules such as oligosaccharides, sIgA and lactoferrin which hold vital importance in immune system. These molecules specifically functioned to protect the body from pathogens including those causing diarrhea. The objective of this study is to define the relationship between exclusive breastfeeding and acute diarrhea incidence frequency in children as primary outcome and age of first acute diarrhea occurrence in children as secondary outcome.Methods: This is an analytic observational cross-sectional study which included 35 children aged 6-24 months who were admitted to Kaswari Ward Wangaya General Hospital Denpasar between 01 June 2018 to 16 August 2018. Samples were obtained through consecutive sampling method and analyzed data were presented in both tables and narrative.Results: From 35 samples included in this study, 13 were exclusively breastfed (37,1%) and 22 were non-exclusively breastfed (62,9%). Sample characteristics including gender, number of siblings, nutritional status, residence, source of water, age of mother, parent’s occupation and education were comparable between two groups. Total samples who were exclusively breastfed and experience less diarrhea is 13 (p = 0,031; PR = 1,47 CI 95% 1,10-1,95). Total samples who were exclusively breastfed and first age of experiencing diarrhea over 12 months old is 11 (p = 0,002 ; PR = 3,10 CI 95% 1,47-6,27). Conclusion: There is statistically significant relationship between exclusive breastfeeding and acute diarrhea incidence frequency and age of first acute diarrhea occurrence in children aged 6-24 months in Kaswari Ward Wangaya General Hospital.

Exclusive Breastfeeding And Acute Diarrhea In Children: A Cross-Sectional Study Lukman, Leni; Suryawan, I Wayan Bikin
Medicinus Vol. 8 No. 2 (2019): February : 2019
Publisher : Fakultas Kedokteran Universitas Pelita Harapan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19166/med.v7i4.2383

Introduction : Breastmilk is known to contain molecules such as oligosaccharides, sIgA and lactoferrin which hold vital importance in immune system. These molecules specifically functioned to protect the body from pathogens including those causing diarrhea. The objective of this study is to define the relationship between exclusive breastfeeding and acute diarrhea incidence frequency in children as primary outcome and age of first acute diarrhea occurrence in children as secondary outcome.Methods: This is an analytic observational cross-sectional study which included 35 children aged 6-24 months who were admitted to Kaswari Ward Wangaya General Hospital Denpasar between 01 June 2018 to 16 August 2018. Samples were obtained through consecutive sampling method and analyzed data were presented in both tables and narrative.Results: From 35 samples included in this study, 13 were exclusively breastfed (37,1%) and 22 were non-exclusively breastfed (62,9%). Sample characteristics including gender, number of siblings, nutritional status, residence, source of water, age of mother, parent’s occupation and education were comparable between two groups. Total samples who were exclusively breastfed and experience less diarrhea is 13 (p = 0,031; PR = 1,47 CI 95% 1,10-1,95). Total samples who were exclusively breastfed and first age of experiencing diarrhea over 12 months old is 11 (p = 0,002 ; PR = 3,10 CI 95% 1,47-6,27). Conclusion: There is statistically significant relationship between exclusive breastfeeding and acute diarrhea incidence frequency and age of first acute diarrhea occurrence in children aged 6-24 months in Kaswari Ward Wangaya General Hospital.

Coverage and Knowledge Regarding Human Papillomavirus Vaccination Among Female Medical Students at Pelita Harapan University Lukman, Leni
Medicinus Vol. 14 No. 3 (2025): June
Publisher : Fakultas Kedokteran Universitas Pelita Harapan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19166/med.v14i3.10148

Background: Cervical cancer is the fourth most common cancer among women worldwide. Human papillomavirus (HPV) is the primary cause of cervical cancer. One of the key preventive measures to reduce the incidence of cervical cancer is immunization. According to the data from the World Health Organization year 2020, the national HPV vaccination coverage in Indonesia was only 5% for the complete dose and 6% for the first dose. Lack of knowledge is one of the contributing factor of HPV vaccination coverage. Methods: This study was conducted with cross-sectional design. This study used primary data which was collected using questionnaires. The questionnaire has been tested for validity and reliability in previous study. The subjects were female students of Faculty of Medicine University of Pelita Harapan. Results: Our of 770 subjects with mean age of 20.3 years old, 490 subjects (63.6%) never got HPV vaccination, 102 subjects (13.3%) were not fully vaccinated and 178 subjects (23.1%) were fully vaccinated. Age at first dose of HPV vaccination was 9-14 years old in 123 subjects (43.9%) and > 15 years old in 157 subjects (56.1%). From all of the HPV vaccinated subjects, 18 subjects (6.4%) got bivalent vaccine, 52 subjects (18.6%) got quadrivalent vaccine and 64 subjects (22.9%) got nonvalent vaccine. Majority of the subjects (354 subjects, 46%) had good knowledge regarding HPV vaccination, 271 subjects (35.2%) had sufficient knowledge and 145 subjects (18.8%) had poor knowledge. Conclusions: Despite sufficient knowledge regarding HPV vaccination among majority of female medical students at Pelita Harapan University, HPV vaccination coverage remained suboptimal.

⁠Dapsone Induced Methemoglobinemia in Pediatric Patient: A Case Report Addyanto, Brian; Lukman, Leni
Medicinus Vol. 15 No. 1 (2025): October
Publisher : Fakultas Kedokteran Universitas Pelita Harapan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19166/med.v15i1.10767

Background: Acquired methemoglobinemia is significantly more common than the congenital form, though it remains a rare condition. Most cases arise from accidental chemical exposure or the use of topical and local anesthetics. Case Description: We present a case of 14-year-old male presented with complaints of dark grayish discoloration of the skin on the face and hands, persisting for the past two months prior to admission. He was later diagnosed with dapsone induced methemoglobinemia. Patient was then discharged with oral therapy consisting of agents with antioxidant properties and instructed to discontinue dapsone consumption. Conclusions: In pediatric patients undergoing dapsone therapy, the risk of dapsone induced methemoglobinemia should be carefully considered to ensure early identification and prompt management, thus minimizing the potential for severe complications.

Perbandingan Efikasi dan Keamanan Parasetamol serta Ibuprofen dengan Dosis Berdasarkan Berat Badan dalam Penanganan Demam Anak: Uji Klinis Acak Terbuka Prawira, Yogi; Agustina, Agustina; Hamik, Welli; Santi, Theresia; Garniasih, Dina; Tandra, Irene Mutiara; Lukman, Leni; Sugiharto, Jessica; Ardini, Ni Putu
Sari Pediatri Vol 27, No 5 (2026)
Publisher : Badan Penerbit Ikatan Dokter Anak Indonesia (BP-IDAI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14238/sp27.5.2026.299-308

Latar belakang. Demam adalah keluhan tersering di praktik pediatri Indonesia. Parasetamol dan ibuprofen menjadi antipiretik utama, baik dengan pengawasan medis maupun swamedikasi. Namun, sebagian besar produk di Indonesia masih menggunakan panduan dosis berbasis usia, padahal variasi berat badan anak yang lebar berisiko menyebabkan dosis kurang atau berlebih.Tujuan. Menilai efikasi dan keamanan pemberian tunggal parasetamol dan ibuprofen berbasis berat badan dalam menurunkan demam pada anak usia 2-15 tahun di Indonesia.Metode. Penelitian ini merupakan uji klinis fase III, acak terbuka, dua lengan paralel, non-inferioritas, dan multisenter. Subjek diacak menerima parasetamol sirup 250 mg/5 mL (10-15 mg/kg) atau ibuprofen suspensi 100 mg/5 mL (5-10 mg/kg). Suhu timpani diukur pada menit ke-15, 30, 60, 120, 180, dan 240 setelah pemberian pertama. Keamanan dievaluasi melalui efek samping serta pemeriksaan hematologi, fungsi hati dan ginjal, dan CRP dalam 48-72 jam setelah dosis terakhir.Hasil. Sebanyak 93 anak dibagi menjadi dua kelompok: parasetamol (45 anak) dan ibuprofen (48 anak). Penurunan suhu mulai terlihat pada 15 menit pertama (rata-rata 0,55°C). Pada menit ke-60, penurunan suhu kedua obat sebanding (parasetamol 1,13°C; ibuprofen 1,06°C). Pada menit ke-240, ibuprofen unggul 0,20°C, tetapi masih dalam batas non-inferioritas (0,65°C). Efek samping ringan dan sementara, tanpa kejadian serius. Laboratorium menunjukkan peningkatan ringan enzim hati (?7 U/L) dan penurunan CRP ±17 mg/L, sesuai proses penyembuhan alami.Kesimpulan. Dosis parasetamol dan ibuprofen berbasis berat badan terbukti cepat, aman, dan setara dalam menurunkan demam anak Indonesia. Keduanya dapat menjadi terapi lini pertama yang fleksibel. Temuan ini mendukung penerapan panduan dosis berbasis berat badan (mg/kg) menggantikan panduan berbasis usia.

Title

Found 5 Documents
Search

Abstract

Abstract

Abstract

Abstract

Abstract

Title Search

Found 5 Documents Search

Abstract

Abstract

Abstract

Abstract

Abstract

Title

Found 5 Documents
Search