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All Journal BALI MEDICAL JOURNAL (BMJ) Medicina Sari Pediatri Paediatrica Indonesiana Medicinus : Jurnal Kedokteran ISM (Intisari Sains Medis) : Jurnal Kedokteran Bioscientia Medicina : Journal of Biomedicine and Translational Research Journal of the Indonesian Medical Association : Majalah Kedokteran Indonesia Jurnal Ilmiah Permas: Jurnal Ilmiah STIKES Kendal Jurnal Prima Medika Sains Bioscientia Medicina : Journal of Biomedicine and Translational Research Jurnal Kedokteran Meditek
I Wayan Bikin Suryawan
Bagian/SMF Ilmu Kesehatan Anak Fakultas Kedokteran Universitas Udayana/RSUP Sanglah, Denpasar
Biochemistry, Genetics & Molecular Biology Education Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Nursing Public Health Veterinary

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OSTEOPOROSIS IN A SEVENTH YEAR OLD BOY WITH ACUTE LYMPHOBLASTIC LEUKEMIA (Case Report) Salim, H; Ariawati, K.; Bikin-Suryawan, W.; Arimbawa, and I. M.
BALI MEDICAL JOURNAL Vol 2 No 3 (2013): Vol.2, No.3, September-December 2013
Publisher : BALI MEDICAL JOURNAL

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Abstract

Osteoporosis in children is rare and usually secondary to an underlying disease process whose diagnosis may be difficult to detect. It can be a manifestation of acute lymphoblastic leukemia (ALL). About a-quarters of children with ALL will have signs and symptoms of osteoporosis. We report the case of a seventh-year-old boy with back pain. His antero-posterior pelvic radiograph showed the osteoporotic bone. The bone age study revealed six-year-old bone. Review of peripheral blood smear showed normochromic anemia with thrombocytopenia. Immunophenotyping of peripheral blood revealed no dominant marker was seen, but the bone marrow aspiration confirms the diagnosis of ALL (L2).
SECKEL SYNDROME IN A - 2 YEAR OLD GIRL Yulius Malino, Imanuel; Arimbawa, Made; Suryawan, Bikin
Medicina Vol 44 No 1 (2013): Januari 2013
Publisher : Medicina

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Abstract

Seckel syndrome is a frequent autosomal recessive that cause microcephalic osteodysplastic dwarfisms. It characterized with proportionate dwarfism of prenatal onset, dysmorphic features including severe microcephaly and “bird-headed” like appearance, mental retardation and autosomal recessive inheritance, becausedefect on chromosome 3q22.1-q24 (SCKL1), chromosome 18p11.31-q11.2 (SCKL2) and chromosome 14q23 (SCKL3). We reported, 2 years, 8 months female with intrauterine growth restriction, severe proportionately short stature, a “bird-headed” profile with receding forehead, large eyes, breaks like protrusion of the nose, narrow face, receding lower jaw and micrognathia and from bone survey we found a retarded bone age on which was appropriate for 6 months of age.There was no other systems dissorder have been found and no specific medication has been given. Patient was hospitalized to establish diagnosis and was dischargedafter ten days of hospitalization
CORRELATION BETWEEN PENIS LENGTH AND ANTHOPOMETRY OF 5 YEAR OLD CHILDREN Kurnia Indrawan, Doddy; Suryawan, Bikin; Sidiartha, Lanang; *, Arimbawa
Medicina Vol 43 No 1 (2012): Januari 2012
Publisher : Medicina

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Abstract

Short penis still a problem for parents. Penis lenght is associated with  weight and considered abnormal in obese children. The purpose of this study was to find out the correlation between penis length and the anthropometry children aged 5 years. A cross sectional study was conducted, at the Division of Endocrinology, Department of Child Health, Medical Faculty of Udayana University, Sanglah Hospital Denpasar, during October 2010, at TK Sayang Ibu Sanglah Hospital. The calculation of the sample with a correlation coefficient of weight and  height obtained  9 people, taking in consecutive sampling and analyzed  with Pearson’s correlation. The mean body weight was 23.6 (SD 7.70) kg;  mean child height was 108.4 (SD 5.3) cm, and 47.1% were obese. The mean length of the penis was 4.7(SD1.30) cm. The correlation between weight and penis lenght was strong negative (r = -0.876; P = 0.000) and between penis length and height was r = -0.597; P = 0,011.There was a strong negative correlation between body weight and penis length and also negative correlation between penis length and height in kindergarten children. (MEDICINA 2012;43:19-22).
HIPERPLASIA ADRENAL KONGENITAL (HAK) KLASIK SIMPLE VIRILIZING PADA ANAK UMUR 3 TAHUN Indradjaja, Alice; Bikin Suryawan, I Wayan; Arimbawa, I Made
Medicina Vol 45 No 1 (2014): Januari 2014
Publisher : Medicina

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Abstract

Hiperplasia adrenal kongenital merupakan salah satu dari kelompok kelainan genetik akibat defisiensi enzim yang diperlukan untuk biosintesis steroid di korteks kelenjar adrenal. Bentuk kelainan hiperplasia adrenal kongenital yang tersering adalah defisiensi enzim 21-hidroksilase (21OHD) hingga mencapai 90% kasus. Kelainan utama pada pasien dengan defisiensi enzim 21-hidroksilase adalah kegagalan sintesis kortisol secara adekuat. Defisiensi 21-hidroksilase klasik tipe virilisasi sederhana menyebabkan genitalia ambigu pada bayi perempuan. Dilaporkan sebuah kasus hiperplasia adrenal kongenital klasik tipe virilisasi sederhana pada anak perempuan usia tiga tahun. Pasien dirujuk ke Poliklinik anak RSUP Sanglah Denpasar dengan keluhan utama pembesaran dan pemanjangan klitoris yang progresif disertai tumbuhnya bulu pubis.  Pasien lahir dengan genitalia ambigu. Pasien didiagnosis defisiensi 21-hidroksilase berdasarkan hasil pemeriksaan kadar progesteron 17-OH >1.200ng/dl dan pemeriksaan fisik didapatkan prader derajat III. Pada pemeriksaan usia tulang menunjukkan usia tulang yang melebihi umurnya, USG abdomen dalam batas normal dengan hasil analisis kromosom 46,XX. Pasien tidak pernah mengalami krisis adrenal selama 3 tahun dan menjalani tindakan pembedahan pada usia 3 tahun. Keluarga pasien diberikan konseling, dilakukan monitor  berkala pada pasien dan terapi hidrokortison. Prognosis pada pasien ini baik. [MEDICINA 2014;45:58-64].
PREVALENCE AND ASSOCIATION OF GLYCOSURIA WITH SEVERAL RISK FACTORS FOR DIABETES MELLITUS IN PRIMARY SCHOOL CHILDREN IN BALI Sutawan, Ida Bagus Ramajaya; Suryawan, I Wayan Bikin; Arimbawa, I Made
Medicina Vol 45 No 3 (2014): September 2014
Publisher : Medicina

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Abstract

Nowadays, diabetes mellitus (DM) is often found in children. One of important screening for DM isurine examination to determine glycosuria. The current data on the prevalence of glycosuria in childrenin Indonesia, including Bali is very limited.The purpose of this study is to determine the prevalence ofglycosuria in primary school children in Bali and the association of several risk factors for DM on theoccurrence of glycosuria.A cross sectional study of children aged 6-12 years in several primary schoolsin Bali was done. Samples were taken using multistage random sampling technique. Glycosuria wasdetermined by urine reagent stripsand determination of risk factors for DM was by questionnaire andphysical examination. Total of 1020 children were examined in this study. Fiftyone point five percentsof samples were male, obesity was found in 36.8% of samples. Family history of DM was found in 2.6%of samples. This study found 17 cases of glycosuria with a prevalence of 1.7%. Several factors werefound associated with glycosuria, including obese with OR 5.32 (95% CI 1.65 to 17.16; P=0.005), familyhistory of DM with OR 12.98 (95% CI 3.11 to 54.27; P<0.001), and male gender with OR 6.05 (CI 95%1.34 to 27.33; P=0.019).Based on this study, it could be concluded thatthe prevalence of glycosuria wasquite high at primary school children in Bali. Therefore glycosuria screening in children needs to bedone,  especially  in  those with  risk  factors  for DM  to  detect  this  disease  earlier.  [MEDICINA2014;45:156-160].
CASE REPORT KALLMANN SYNDROME IN A 14-YEAR-OLD BOY Anggraeni, Melisa; Arimbawa, Made; Suryawan, IW Bikin
Medicina Vol 44 No 1 (2013): Januari 2013
Publisher : Medicina

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Abstract

Kallmann syndrome is a combination of hypogonadotropic–hypogonadism due to gonadotropine releasing hormone (GnRH) deficiency with anosmia or hyposmia. Magnetic resonance imaging (MRI) reveals hypoplasia or aplasia of the olfactory bulbs. The incidence is estimated at 1 in 10.000 and 50.000 males and females respectively. The main clinical features consists of the absence of spontaneous puberty, partial or total loss of the sense of smell (anosmia). In this case report, we describe a 14 year old boy with Kallmann syndrome who was refferred with delayed puberty and lack of smell function. Physical examination revealed Tanner stage I and proven anosmia from olfactory test. Laboratory test showed low titer of testosteron. Testicular ultrasonography (USG) revealed small testicles. Treatment of this particular patient was with a 25 mg of intramuscular testosterone injection and were then increased by 25 mg every two weeks. Proper management of patients with Kallmann syndrome usually allows them to attain normal reproductive health.
CLINICAL AND LABORATORY FEATURES OF PATIENTS WITH CONGENITAL HYPOTHYROIDISM -, Widiasa; Suryawan, Bikin
Medicina Vol 38 No 1 (2007): Januari 2007
Publisher : Medicina

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Abstract

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FAKTOR-FAKTOR YANG MEMPENGARUHI KEBERHASILAN ASI EKSKLUSIF PADA ANAK DI RSUD WANGAYA Bella Kurnia; I Wayan Bikin Suryawan
Majalah Kedokteran Indonesia Vol 69 No 10 (2019): Journal of the Indonesian Medical Association Majalah Kedokteran Indonesia Volu
Publisher : PENGURUS BESAR IKATAN DOKTER INDONESIA (PB IDI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.1234/jinma.v69i10.178

Abstract

Latar Belakang: ASI merupakan makanan alamiah terbaik bagi bayi. ASI mengandung nutrisi penting untuk bayi seperti protein, lemak, karbohidrat, vitamin, mineral, dan berbagai macam elemen penting untuk bayi dalam mencapai tumbuh kembang yang optimal. Di Indonesia, angka cakupan ASI masih dibawah target. Penelitian ini dilakukan untuk melihat faktor yang mempengaruhi keberhasilas ASI eksklusif pada anak di RSUD Wangaya. Metode: Desain penelitian ini adalah kasus-kontrol. Data diambil dari data rekam medis serta wawancara di RSUD Wangaya sejak April hingga Mei 2019. Studi ini menggunakan consecutive sampling. Analisis data menggunakan chi-square untuk bivariat dan regresi logistik untuk multivariat. Hasil: Faktor-faktor yang dianalisis yaitu multipara (p=1,000; OR=1.214), metode persalinan (p=1,000; OR=1.214), ketersediaan informasi (p&lt;0,001; OR=46.000), pekerjaan (p=0,148; OR=2.778), dan tingkat pendidikan (p=0,240; OR=2.364). Dari analisis multivariat, terdapat satu faktor yang berpengaruh yaitu ketersediaan informasi (p=0,001). Kesimpulan: Fakor yang mempengaruhi keberhasilan ASI eksklusif pada anak di RSUD Wangaya adalah ketersediaan informasi tentang ASI terhadap ibu.
Pengaruh Kortikosteroid Inhalasi terhadap Pertumbuhan IB Mahendra; Soetjiningsih Soetjiningsih; Bikin Suryawan
Sari Pediatri Vol 9, No 3 (2007)
Publisher : Badan Penerbit Ikatan Dokter Anak Indonesia (BP-IDAI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14238/sp9.3.2007.196-200

Abstract

Pertumbuhan normal dipengaruhi oleh berbagai faktor termasuk faktor endokrin, lingkungan, nutrisi danpengaruh genetik. Gangguan pada pola pertumbuhan merupakan indikator penting adanya gangguanmedis yang serius. Gangguan pertumbuhan akibat penggunaan kortikosteroid inhalasi dalam waktu yanglama telah menjadi perdebatan para praktisi. Meskipun pengaruh kortikosteroid terhadap penghambatanpertumbuhan telah lama diketahui namun mekanismenya tidak sepenuhnya diketahui. Kortikosteroidinhalasi dalam menekan pertumbuhan tergantung besar dosis dan lamanya pengobatan serta frekuensipemberiannya
Gambaran Klinis Kriptorkismus di Poliklinik Endokrinologi Anak RS Dr. Cipto Mangunkusumo, Jakarta, Tahun 1998 - 2002 Wayan Bikin Suryawan; Jose RL Batubara; Bambang Tridjaja; Aman B Pulungan
Sari Pediatri Vol 5, No 3 (2003)
Publisher : Badan Penerbit Ikatan Dokter Anak Indonesia (BP-IDAI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (201.799 KB) | DOI: 10.14238/sp5.3.2003.111-6

Abstract

Latar belakang: kriptorkismus merupakan kelainan organ seksual lelaki yang seringditemukan. Sampai berapa tahun terapi hormonal dan pembedahan dilakukan masihkontroversial.Tujuan: penelitian ini bertujuan untuk mengetahui umur saat berobat pertama kali, asalrujukan, lokasi testis, peran perabaan, penyakit penyerta, dan peran terapi hormonalpada kriptorkismus.Cara kerja: Penelitian dilakukan secara retrospektif dari semua pasien baru yang didiagnosiskriptorkismus di Poliklinik Endokrinologi Anak RSCM selama 5 tahun (Januari 1998 –Desember 2002).Hasil: diteliti 63 pasien baru, 58 pasien diantaranya dengan kriptorkismus murni, dan 5 pasientestis retraktil. Didapat 22,4% kriptorkismus bilateral, 77,6% kriptorkismus unilateral,kriptorkismus kanan dan kiri jumlahnya hampir sama. Pasien yang dirujuk oleh spesialis anak33,3%. Umur pertama datang di poliklinik 9 bulan-2 tahun 24,1%, dan >2 tahun 56,9%.Pada perabaan, lokasi testis paling banyak tak teraba 74,1%, setelah dikonfirmasi dengan USG75% hasilnya sama dengan perabaan. Kriptorkismus disertai skrotum bifidum dan hipospadia12,6%, mikropenis 11,1%, sindrom Prader Willi, sindrom Noonan, sindrom Kallmann masingmasing1,6% dan merupakan penyakit dasar kriptorkismus. Keberhasilan Terapi hormonal65% ( inguinal 77,8% dan pada testis tak teraba 50%) , terapi dimulai sejak umur 9 bulan.Kesimpulan: sebagian besar pasien datang pada umur >2 tahun, sedangkan terapihormonal dimulai pada umur 9 bulan dengan keberasilan 65%. Pemeriksaan fisik samaakurat dibandingkan dengan pemeriksaan USG. Terapi hormonal pada kriptorkismusumur 6 bulan - 2 tahun masih efektif sebelum terapi bedah dilakukan.
Co-Authors A.A Made Sucipta A.A Made Widiasa A.A. Made Sucipta A.A. Made Widiasa Adi Wirawan Alberto Afrian Alice Indradjaja, Alice Aman B Pulungan Anak Agung Made Sucipta Anak Agung Made Sucipta Anak Agung Made Sucipta Anak Agung Made Sucipta Anak Agung Made Sucipta Anak Agung Made Sucipta, Anak Agung Made Anak Agung Made Widiasa Anak Agung Made Widiasa Anak Agung Made Widiasa Andreas Eric Andrew Permana Suliarta Arimbawa * Ayu Setyorini Mestika Mayangsari Bambang Tridjaja AAP, Bambang Tridjaja Bella Kurnia Bella Kurnia Bella Kurnia Cahaiantari, Ni Putu Elis Callista Beatrice Christina, Jessica Chyntia Conchita Christal Yasadipura Cynthia Cynthia Cynthia Cynthia Cynthia Cynthia Cynthia Jodjana Dewi, Made Ratna Doddy Kurnia Indrawan Edbert Wielim Elien Yuwono Erica Lidya Yanti Gosal, Jessica H Salim I Dewa Gede Ugrasena I Gde Doddy Kurnia Indrawan, I Gde Doddy Kurnia I Gusti Amanda Jaya I Gusti Lanang Sidiartha I Kadek Serisana Wasita I Kadek Suarca I Kadek Suarca I Made Arimbawa IB Mahendra Ida Bagus Ramajaya Sutawan, Ida Bagus Ramajaya Ida Bagus Wiadnyana IKG Suandi IM Widiaskara Imanuel Yulius Malino Jeven Reggie Santoso Jose RL Batubara Kadek Suarca Kadek Suarca Ketut Ariawati Komang Tria Anggareni Lukman, Leni Made Cynthia Mahardika Putri Made Dwi Purnami Made Ratna Dewi Made Ratna Dewi Made Widiasa Mayland Margaretha Sunata Melisa Anggraeni Mustika, Putu Pradnyanita PT Pramitha Putri Widyastiti, Ni Nyoman Putu Andrie Setiawan Putu Pramitha Rahayu Regina Suriadi Ruby Kurniawan Soetjiningsih Soetjiningsih Soetjiningsih Soetjiningsih Sriwaningsi, Lina Stanley Haryono Suarca, I Kadek Sukarno, Theodora Sunartini Sunartini Suriadi, Regina Susan Natalia Budihardjo sutanti sutanti Valerie Michaela Wilhelmina Widiasa - Wielim, Edbert William Grandinata Soeseno