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PERBANDINGAN KADAR D-DIMER PADA PASIEN CORONA VIRUS DISEASE 2019 (COVID-19) KOMORBID DAN NON KOMORBID DI RUMAH SAKIT RUJUKAN KHUSUS COVID-19 PEKANBARU Agung, Panji; Octariany, Octariany
Jurnal Ilmu Kesehatan Abdurrab Vol 1 No 3 (2023): Volume 1 Nomor 3 September 2023
Publisher : LPPM Universitas Abdurrab

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Abstract

Background : Coronavirus disease 2019 (COVID-19) is a disease caused by betacoronavirus, an RNA virus genome, known as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Several specific markers are needed in assessing the severity of COVID-19, including D-Dimer. D-Dimer is a byproduct of the blood clotting and breakdown process that can be measured through analysis of a blood sample. D-Dimer is released when blood clots begin to break down. D-Dimer is widely used as an indicator of inflammation. In viral infections including COVID- 19, D-Dimer levels will quickly increase. The increase in D-Dimer in patients affected by COVID-19 is exacerbated by the presence of comorbidities. Comorbidity is the occurrence of several chronic or acute medical diseases or conditions in one individual. This research was conducted at Arifin Achmad Regional General Hospital which is a referral hospital that handles COVID-19 cases and has a treatment bed for COVID-19 cases which has an isolation room for COVID-19 patients.Objective: Analyze the comparison of D-Dimer levels of COVID-19 patients with and without comorbidities.Method: This study was a comparative quantitative analytical study with a Cross-sectional approach conducted to see the comparison of D-Dimer levels with COVID-19 patients with and without comorbidities, the samples used were 60 medical record data of patients confirmed with COVID-19 divided into 2 groups consisting of COVID-19 patients with comorbidities and without comorbidities, then bivariate analysis of the Mann whitney test was carried out.Results: The results showed that the most common types of comorbidities in COVID-19 patients were comorbid diabetes mellitus and hypertension. In COVID-19 patients with comorbidities, D-Dimer levels were low (57.7%) and high (43.3%). In non-comorbid COVID-19 patients, D-Dimer levels were low (76.7%) and high (23.3%). The Mann Whitney test obtained a result of 0.007 which means there is a significant difference. Conclusion: In the Mann Whitney test, results were obtained with the conclusion that there was no significant difference between D-Dimer levels in comorbid and non-comorbid COVID-19 patients with a P value of 0.007.
Hubungan Kepatuhan Minum Obat Terhadap Kualitas Hidup Pasien Tuberkulosis Di Puskesmas Rejosari Octariany, Octariany; Sabira, Sausan
Cerdika: Jurnal Ilmiah Indonesia Vol. 5 No. 2 (2025): Cerdika: Jurnal Ilmiah Indonesia
Publisher : Publikasi Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59141/cerdika.v5i2.2518

Abstract

Tuberkulosis merupakan penyakit menular yang diakibatkan oleh bakteri Mycobacterium tuberculosis. Penyakit ini mengakibatkan berbagai perubahan pada penderitanya, baik dari segi fisik, fungsional, psikologis, maupun sosial. Tujuan pengobatan tuberkulosis adalah untuk menyembuhkan pasien, mencegah kekambuhan, dan menghindari resistensi terhadap obat anti tuberkulosis (OAT). Kepatuhan dalam mengonsumsi obat anti tuberkulosis sangat berkaitan dengan kualitas hidup pasien yang menderita tuberkulosis. Pemahaman tentang pentingnya mengonsumsi OAT secara teratur dapat mengurangi gejala yang timbul dari penyakit serta meningkatkan kepatuhan pasien sehingga berguna untuk mencapai kualitas hidup yang lebih baik. Pada tahun 2022, kasus TB di Puskesmas Rejosari sekitar 93 orang, di mana angka kesembuhan dan angka pengobatan lengkapnya cukup rendah yaitu 55,9% dan 40,2%. Penelitian ini menggunakan desain studi analitik observasional dengan rancangan cross sectional. Penelitian ini dilakukan di Puskesmas Rejosari. Teknik pengambilan sampel dengan menggunakan Accidental sampling. Dari 40 responden didapatkan 34 orang dengan kategori kepatuhan minum obat tinggi yaitu 30 orang (75%) memiliki kualitas hidup baik dan 4 orang (10%) dengan kualitas hidup sedang, sementara kategori kepatuhan minum obat sedang sebanyak 6 orang yakni 1 orang (2,5%) kualitas hidup baik dan 5 orang (12,5%) kualitas hidup sedang. Berdasarkan hasil uji korelasi Spearman, diperoleh p-value sebesar 0,004, yang menunjukkan adanya hubungan signifikan antara kepatuhan dalam mengonsumsi obat dengan kualitas hidup pasien tuberkulosis di Puskesmas Rejosari, dengan koefisien korelasi sebesar 0,447.