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All Journal Indonesian Journal of Cancer
Pradipta, Jaka
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Biochemistry, Genetics & Molecular Biology Immunology & microbiology Medicine & Pharmacology Public Health

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Diagnostic Accuracy of Modalities for Diagnosis of Thoracic Cancer: Retrospective Analysis Ariawan, Wily Pandu; Hanafi, Arif Riswahyudi; Pradipta, Jaka; Jayusman, Mulawarman; Hanif, Muhammad Alfin; Hutabarat, Jubillete Windy; Amira, Salsabila Nur
Indonesian Journal of Cancer Vol 19, No 3 (2025): September
Publisher : http://dharmais.co.id/

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33371/ijoc.v19i3.1307

Abstract

Background: Thoracic cancer becomes a huge consideration, especially for lung cancer, because it quietly increases over time and needs highly sensitive diagnostic modalities. Thus, we aim to investigate the diagnostic accuracy of several cytology-based modalities to diagnose thoracic cancer. It would serve as a reference for other cancer centers in estimating diagnostic approaches for thoracic cancer.Method: Retrospective analysis with a cross-sectional study comprised of 2358 diagnostic procedures at Dharmais Cancer Hospital, Jakarta, Indonesia, from 2020 to 2023. Data were extracted from e-medical records. We compared seven cytology-based procedures to the gold standard, which is histopathology examination. Results: Study subjects (n=2358; mean age 60 ± 12.0; 62.6% male) predominantly used the mode of diagnostic Bronchial Brushing Cytology (BBC) about 676 (28.7%). Endobronchial Ultrasound (EBUS) was the highest sensitivity (88.1%) of the diagnostic approach for thoracic cancer (p 0.05).Conclusion: EBUS had the highest sensitivity in diagnosing thoracic cancer. However, multimodality diagnostic procedures should be considered for patients who have symptoms suggestive of thoracic cancer to get highly positive results and lower complications, both cytologically and histologically. As a national cancer center, providing data on diagnostic modalities is necessary, and an analysis of cancer services is required for informed policy recommendations.
Factor Associated with Mortality of Hospitalized Cancer Patients with COVID-19 Infection in Indonesia National Cancer Center Kurniawati, Sri Agustini; Sutandyo, Noorwati; Tadjoedin, Hilman; Pradipta, Jaka; Ismuha, Ratu Ralna; Ummah, Citra Dovina Khaira; Suryana, Kresna Dharma; Budi, Erwin
Indonesian Journal of Cancer Vol 18, No 2 (2024): June
Publisher : http://dharmais.co.id/

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33371/ijoc.v18i2.1077

Abstract

Background: Cancer patients with COVID-19 are at risk of developing severe complications and outcomes due to immunosuppressive and inflammatory states. This study aims to provide insight into risk factors associated with mortality in this population. Methods: A retrospective cohort study was conducted at Dharmais National Cancer Center, Jakarta, Indonesia, from May 2020 to July 2021. Data were collected through electronic medical records using the consecutive sampling technique. The numerical and categorical data were then tested statistically. Results: The results showed 180 cancer patients with COVID-19 were hospitalized at Dharmais National Cancer Center. Among the patients, 114 patients survived, and 66 patients deceased. Across all risk factors analyzed to mortality, patients with Diabetes Mellitus (OR 0.41;0.22-0.77, p-value 0.05) and high level of D-dimer (OR 2.00;1.06-3.79, P-value 0.05) have a higher risk in mortality. The Results showed that survived patients have lower D-dimer levels (2010 ng/L) and deceased patients have higher D-dimer levels (3264 ng/L) with P-value 0.05. Conclusion: High D-dimer levels and diabetes are risk factors significantly associated with mortality in hospitalized cancer patients with COVID-19 Infection.
Co-Authors Amira, Salsabila Nur Ariawan, Wily Pandu Budi, Erwin Hanafi, Arif Riswahyudi Hanif, Muhammad Alfin HILMAN TADJOEDIN, HILMAN Hutabarat, Jubillete Windy Jayusman, Mulawarman Noorwati Sutandyo Ratu Ralna Ismuha Sri Agustini Kurniawati, Sri Agustini Suryana, Kresna Dharma Ummah, Citra Dovina Khaira