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THE EFFECTS OF AEROBIC EXERCISE AND DETRAINING ON LEFT VENTRICULAR CARDIOMYOCYTE APOPTOSIS Putri, Mustika
Jurnal Kedokteran YARSI Vol 24, No 3 (2016): SEPTEMBER - DESEMBER 2016
Publisher : Lembaga Penelitian Universitas YARSI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33476/jky.v24i3.276

Abstract

Apoptosis can occur in several pathological heart conditions. Physical exercise, particularly aerobic exercise may reduce apoptosis on cardiomyocytes. Detraining can restore adaptation after exercise. This study aimed to see the effect of aerobic exercise and detraining on left ventricular cardiomyocyte apoptosis using caspase-3 as the parameter.This was an in vivo experimental study on Wistar rats Rattus Novergicus. Rats divided to 8 groups: 4 sedentary control groups: 4-week (C4), 8-week (C4D), 12-week (C12), 16-week control (C12D), and 4 aerobic exercise treatment groups: 4-week (A4) and 12-week (A12), and 4 12-week post aerobic exercise treatment followed by 4 weeks detraining (A4D, A12D). Caspase-3 protein in rat left ventricular tissue was identified by immunohistochemistry staining. Data were analized with ANOVA test using SPSS proggramme version 20.Data analysis showed an increase percentage of caspase-3 expression on post-aerobic exercise (A), be compared with conntrol group (C) (A4 65,3%±2,54 vs K4 6,4%±1,78, p 0,001; A12 41,8%±3,21 vs K12 5,7%±0,88, p 0,001; A4D 66,6%±1,89 vs K4D 8,6%±3,60, p 0,001; A12D 45,1%±1,50 vs K12D 7,4%±2,06, p 0,001). Percentage of caspase-3 expression was not different on post-aerobc exercise (A), be compare with detraining group (A4D 66,6%±1,89% vs A4 65,4%±2,54, p=0,484; A12D 45,1%±1,50 vs A12 41,8%±3,21, p=0,063). Percentage of caspase-3 expression on post 4-week aerobic exercise group was higher than post12-week aerobic exercise (A4 65,4%±2,54 vs A12 41,8%±3,21, p 0,001).In conclusion, the aerobic exercise protocol used in this study, was not found to decrease left ventricular cardiomyocyte apoptosis. Detraining did not increase left ventricular cardiomyocyte apoptosis.
Pemanfaatan Arang Kayu, Tempurung an Sabut Kelapa Sebagai Bahan Bakar Pengasapan Ikan Nila (Oreochromis niloticus) Menggunakan Alat Pengasap Ikan Tipe Drum Asmara, Sandi; Putri, Mustika; Oktafri, Oktafri; Kuncoro, Sapto
Jurnal Agricultural Biosystem Engineering Vol 3, No 1 (2024): March 2024
Publisher : abe.fp.unila.ac.id

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23960/jabe.v3i1.8747

Abstract

Tilapia is a freshwater fish that is popular with many people, because its meat tastes savory and delicious. One way to process fish so that it lasts is by smoking the fish. This fish is smoked using a drum type smoker. This research aims to analyze the characteristics of smoked tilapia using several fuel components. The sample used was approximately 36 kg of fresh tilapia fish with fuel consisting of a composition of wood charcoal and coconut husks, wood charcoal and coconut shells, and a composition of coconut shells and coconut husks. The best treatment of the three fuel compositions used is the P2 treatment with a composition of 50% wood charcoal + 50% coconut shell, with an organoleptic value of appearance 8.60, aroma 8.33, taste 8.67 and texture 8.47, which means appearance whole, the color is less shiny, specific to the product, has a specific aroma of smoked fish that is less strong, has a specific taste of smoked fish that is less strong, and has a dense, compact texture, quite tight intertwining which has a weight loss of 35.5%, water content of 54.89% (in accordance with SNI), the yield is 64.49% and the amount of fuel used is 3.6 kg. Keywords:  Coconut Fiber, Coconut Shell, Drum Type Smoker, Tilapia Fish Smoking, Wood Charcoal.