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All Journal Jurnal Farmasi Higea JURNAL MEDIA KESEHATAN Journal Fatmawati Laboratory & Medical Science
Irawan, Putra Adi
Unknown Affiliation
Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Public Health

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COMPARATIVE STUDY: FORMULA PRAKTIS ESTIMASI LAJU FILTRASI GLOMERULUS(LFG) DENGAN BIOMARKER KREATININ SERUM Irawan, Putra Adi; Farizal, Jon; Febrianto, Tedy
JURNAL MEDIA KESEHATAN Vol 12 No 2 (2019): Jurnal Media Kesehatan Poltekkes Kemenkes Bengkulu Volume 12 No 2 Desember 2019
Publisher : Politeknik Kesehatan Kemenkes Bengkulu

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33088/jmk.v12i2.439

Abstract

Background: Estimation GFR is complicated to take a relatively long time, so it takes a practical and efficient method with accurate results as well. Indonesia is a country with moderately high chronic kidney disease patients. Riskesdas Data Ministry of Health 2013-2018 reported patients with kidney failure age ≥ 15 years of increasing each year. It takes several laboratory tests to give a proper picture of kidney health including: LFG. There are several formulas that have been researched earlier by experts including: Formula Chronic Kidney Disease-Epidemiology Collaboration (CKD-EPI), The isotope dilution mass spectrometry (ID-MS) Traceable Modification of Diet in Renal Disease (MDRD) , and Modification of Diet in Renal Disease (MDRD) 4 Variable. Objectives: Know the comparison of LFG estimates based on the formula CKD-EPI, ID-MS Traceable MDRD, and MDRD 4 Variable. Methods: Data used in research studies such as serum creatinine and subject age are obtained from secondary Data as much as 30 people. The GFR values are calculated with the CKD-EPI formula, ID-MS Traceable MDRD, and MDRD 4 Variable. Result: Average value of ± SD (n = 30) LFG based on the CKD-EPI formula is 71,36 ± 8.77 with the vulnerable value of GFR = 50,70-89,34. 93.30% suffered mild (60-89) and 6.70% Moderate damage (59-30). The average value of ± SD (n = 30) GFR based on the formula of the ID-MS Traceable MDRD is 64,79 ± 6,59 with vulnerable value of GFR = 48,48-78,40. 83.30% suffered mild (60-89) and 16.70% Moderate damage (59-30). Average value of ± SD (n = 30) GFR based on the MDRD 4 Variable formula is 68,86 ± 7,00 with vulnerable value GFR = 51,53-83,33. 93.30% suffered mild (60-89) and 6.70% Moderate damage (59-30). Conclusion: The use of three (3) such formulas can be used to estimate GFR. Nevertheless, the formula CKD-EPI or MDRD 4 variables are recommended.
DIVERSITAS GOLONGAN DARAH SISTEM ABO BERDASARKAN RIWAYAT DEMAM BERDARAH DENGUE PADA MAHASISWA DI PADANG HARAPAN KOTA BENGKULU Irawan, Putra Adi; Krisyanella, Krisyanella
JURNAL MEDIA KESEHATAN Vol 13 No 2 (2020): Jurnal Media Kesehatan Poltekkes Kemenkes Bengkulu Volume 13 No 2 Desember 2020
Publisher : Politeknik Kesehatan Kemenkes Bengkulu

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33088/jmk.v13i2.575

Abstract

Abstract Background: Diversity of blood groups based on certain diseases such as dengue is still a concern by a number of researchers. Dengue hemorrhagic fever is still a national health problem. Indonesia is one of the countries that has relatively high dengue cases. Bengkulu Province was previously ranked 26th with a 17.53 morbidity rate in 2017, rising to 3rd place with a morbidity rate of 72.28 per 100,000 population in 2018. Data for the last two (2) years shows that Bengkulu City is one of the areas with the most cases of DHF. Data on the diversity of blood groups in the ABO system based on a history of dengue fever in Padang Harapan, Bengkulu City is still very lacking. There is no definite data either in the relevant Office or Regional and Provincial Hospitals, while cases of Dengue Fever occurs at a rate that fluctuates every year Methods: This study was a non-experimental study with an analytic observational design using a cross-sectional approach. Respondents were students in Padang Harapan, Bengkulu City who were selected based on the inclusion and exclusion criteria of 391 people using purposive sampling technique with an age range of 17-25 years. The study took place from March to November 2020. Blood group data and history of dengue fever were collected using google form and confirmed by laboratory examination. Results: The diversity of blood groups in ABO system students was dominated by blood groups A (32.5%), O (31.2%), B (25.6%), and AB (10.7%). As much as 9.7% of students in Padang Harapan (n = 391) have experienced dengue fever. The diversity of blood groups of students who had dengue fever (n = 38) was dominated by blood type A (44.7%), B (28.9%), O (18.4%), and AB (7.9%). Conclusion: There is a significant relationship (P=0.032) between blood groups and a history of DHF.
Screening Fitokimia Dan Penetapan Potensi Madu Hutan Sebagai Agen Antibakteri Terhadap Bakteri Propinibacterium Acne dan Staphylococcus Aureus Krisyanella Krisyanella; Zamharira Muslim; Resva Meinisasti; Putra Adi Irawan
Jurnal Farmasi Higea Vol 13, No 1 (2021)
Publisher : STIFARM Padang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52689/higea.v13i1.327

Abstract

Madu dapat membantu menekan pertumbuhan bakteri tertentu melalui beberapa mekanisme salah satunya yaitu dari komposisi kandungan senyawa kimia yang berbeda-beda berdasarkan sumber pakan nektarnya. Perbedaan tersebut diduga mempengaruhi perbedaan aktivitas madu sebagai antibakteri. Jerawat adalah peradangan yang terjadi pada kulit akibat adanya infeksi bakteri pada kelenjar minyak yang tersumbat. Bakteri yang umum menginfeksi jerawat adalah  Staphylococcus aureus dan  Propinibacterium acne. Tujuan penelitian adalah untuk mengetahui kandungan fitokimia dan uji aktivitas antibakteri madu hutan asli Bengkulu terhadap bakteri P.acne dan S. Aureus. Desain penelitian yang digunakan dalam penelitian ini adalah eksperimental laboratorium. Pertama ditetapkan dulu kandungan fitokimia sampel madu, kemudian dilanjutkan dengan penetapan aktvitas antibakteri madu hutan terhadap bakteri P. acne dan S. aureus, potensi ini dilihat dari besarnya nilai Konsentrasi Hambat Minimum (KHM). Sampel madu hutan memiliki kandungan metabolit sekunder. Madu A mengandung Alkaloid dan Terpenoid, Madu B mengandung terpenoid, Madu C mengandung Alkaloid, Madu D mengandung Flavonoid dan alkaloid, sementara Madu E dan F mengandung flavonoid. Dari hasil pengujian aktivitas antibakteri sampel madu hutan memiliki aktivitas antibakteri terhadap bakteri S. aureus  dan P.acne, namun efek aktibakteri paling baik terhadap bakteri S.aureus, dimana pada konsentrasi terkecil, madu masih memberikan daya hambat pada bakteri S.aureus. Madu hutan mengandung metabolit sekunder dan  lebih berpotensi sebagai agen antibakteri terhadap bakteri S. aureus  dibandingkan dengan pada bakteri P. acne
KADAR NATRIUM (Na) PENDERITA DM TIPE II DI WILAYAH KERJA PUSKESMAS TELAGA DEWA TAHUN 2024 Zakiya, Assyfa Araiza; Irawan, Putra Adi; Sahidan, Sahidan
Jurnal Fatmawati Laboratory & Medical Science Vol 4 No 1 (2024): Bakteriologi Jilid 2
Publisher : POLTEKKES KEMENKES BENGKULU

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33088/flms.v4i1.617

Abstract

Permasalahan : Diabetes melitus adalah gangguan metabolisme yang ditandai dengan hiperglikemia. Diabetes melitus tipe II ditandai dengan defisiensi insulin relatif karena disfungsi sel beta pankreas dan resistensi insulin pada organ target, disebabkan karena kelainan dalam sekresi insulin, aksi insulin, atau tidak normal pada keduanya. hiperglikemia dapat menyerap air sebanyak mungkin sehingga Menyebabkan meningkatnya kehilangan natrium melalui urin, yang disebut diuresis osmotik. Tujuan : Penelitian ini bertujuan untuk mengetahui gambaran kadar natrium (Na) berdasarkan karakteristik, usia dan jenis kelamin pada penderita DM Tipe II di wilayah kerja Puskesmas Telaga Dewa tahun 2024. Metode : Jenis penelitian yang digunakan metode deskriptif teknik accidental sampling dengan sampel darah penderita diabetes melitus sebanyak 30 sampel. Hasil : penelitian diperoleh dari kadar Na pada penderita DM Tipe II hampir seluruh 93,3% responden memiliki kadar Na normal, dan kadar Na rendah yaitu 6,7%. Kesimpulan : Pada penelitian ini dapat disimpulkan bahwa terjadi penurunan kadar elektrolit Na terhadap penderita DM Tipe II di Wilayah Kerja Puskesmas Telaga Dewa serta diharapkan agar dapat memperhatikan kesehatan salah satunya memperbaiki gaya hidup dan memperhatikan asupan makanan
Co-Authors Febrianto, Tedy Jon Farizal, Jon Krisyanella Krisyanella Resva Meinisasti Sahidan Sahidan Zakiya, Assyfa Araiza Zamharira Muslim