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All Journal AcTion: Aceh Nutrition Journal Journal of Medical Science; Jurnal Ilmu Medis Rumah Sakit Umum Daerah dr. Zainoel Abidin, Banda Aceh Trends in Infection and Global Health
Setiani, Lily
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Biochemistry, Genetics & Molecular Biology Dentistry Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health

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Analisis Perbedaan Angka Kesintasan pada Pasien Karsinoma Laring Yang Menjalani Total Laringektomi Dengan Dan Tanpa Diseksi Leher Fadhlia; Kurnia , Benny; Setiani, Lily; Fitria, Sova; Denantika, Oktaria; Suhanda, Rachmad
Journal of Medical Science Vol 6 No 1 (2025): Journal of Medical Science
Publisher : LITBANG RSUDZA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55572/jms.v6i1.117

Abstract

Pilihan terapi untuk karsinoma laring yang progresif (T3-T4) adalah operasi, baik untuk tumor laring maupun diseksi nodul pada leher, yang setelah itu dilanjutkan dengan kemoterapi, radiasi atau kombinasi kemoradiasi. Diseksi nodul pada leher dilakukan sesuai stadium penyakit. Sebagian besar pasien yang terdiagnosis pada stadium lanjut atau metastasis nodal regional, umumnya memiliki tingkat kelangsungan hidup 50%. Penelitian ini bertujuan menganalisis perbedaan angka kesintasan pasien dengan karsinoma laring yang telah menjalani total laringektomi dengan atau tanpa diseksi leher. Pengumpulan data menggunakan rekam medis pasien yang berobat ke Departemen THT-BKL RSUD dr. Zainoel Abidin sejak 1 Juli–30 September 2022. Metode penelitian berupa analitik observasional retrospektif dengan desain khusus analisis kesintasan, Diperoleh total 36 subjek, seluruhnya laki-laki, terbanyak (47,2%) pada kelompok usia 56-65 tahun. Mayoritas subjek (97,2%) memiliki riwayat merokok lebih dari 30 tahun, dengan 44,4% lokasi tumor berada di transglotis, dan pasien terbanyak (88,9%) datang ke rumah sakit pada stadium IV, secara histopatologi 75% jenis keratinizing squamous cell carsinoma. Sejumlah 41,7% menjalani total laringektomi saja dan 58,3% menjalani total laringektomi disertai diseksi leher. Hasil analisis kurva Kaplan Meier didapatkan angka bertahan hidup pada total laringektomi rata-rata 33,24 bulan dan 34,29 bulan pada total laringektomi dengan diseksi leher. Penelitian menunjukkan tidak terdapat perbedaan signifikan pada angka kesintasan pasien karsinoma laring yang menjalani total laringektomi dengan dan tanpa diseksi leher.
Management of fibrosarcoma soft palate: A rare case report Sinaga, Jakaria; Kurnia, Benny; Setiani, Lily
Trends in Infection and Global Health Vol 4, No 1 (2024): June 2024
Publisher : School of Medicine, Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24815/tigh.v4i1.38287

Abstract

Soft palate tumors can be categorized as benign or malignant, with malignant tumors being more common than benign ones. Up to 55% of intraoral tumors are found on the palate; thus, they are known as palatal tumors. Many causative or supporting factors may contribute to the development of palatal tumors, such as the long-term use of tobacco and alcohol. A final diagnosis of a palatal tumor is typically achieved through histological examination. This paper aims to present a case involving a patient diagnosed with palatal fibrosarcoma. The patient, a 39-year-old woman, was diagnosed with palatal fibrosarcoma and underwent treatment consisting of Mass Extirpation and Palatoplasty. Relevant evidence and literature were gathered through searches conducted on PubMed, Medline, and manual research. In this specific case, the surgical approach to excise the palatal tumor was determined based on factors such as its size and location. The diagnosis is based on a combination of the patient's medical history, physical examination, and further clinical assessment. Treatment for palatal tumors primarily involves surgery aimedat completely removing the tumor tissue.
Beetroot (Beta vulgaris L.) juice supplementation and hemoglobin response in head and neck cancer patients after chemotherapy Andini, Dena Tria; Kurnia, Benny; Setiani, Lily; Ridwan, Azwar; Haroen, Elvia
AcTion: Aceh Nutrition Journal Vol 10, No 4 (2025): December
Publisher : Department of Nutrition at the Health Polytechnic of Aceh, Ministry of Health

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30867/action.v10i4.2701

Abstract

Anemia frequently occurs in patients with cancer and can worsen due to chemotherapy. The literature on non-pharmacological interventions to increase hemoglobin levels in patients with head and neck cancer following chemotherapy remains limited. This study aimed to measure the effect of beetroot juice supplementation on changes in hemoglobin levels in patients with head and neck cancer who had undergone chemotherapy. Methods: An experimental study with a one-group pretest–posttest design was conducted at dr. Zainoel Abidin General Hospital, Banda Aceh (July–November 2024). The sample consisted of all head and neck cancer patients undergoing chemotherapy cycles I–VI (total sampling, n=40), divided into two treatment groups: 100 g beetroot juice (n=20) and 200 g beetroot juice (n = 20). Hemoglobin levels were measured before and 14 days after the intervention. The analysis was performed using paired t-tests and effect sizes (Cohen’s d). Results: Administration of 100 g of beetroot juice did not significantly alter hemoglobin levels, with an average difference of −0.24 g/dL (p = 0.241). In contrast, the 200-gram dose resulted in a significant increase in hemoglobin levels, with an average difference of +0.44 g/dL (p = 0.016) after 14 days of intervention. Furthermore, the estimated Cohen’s d (pooled SD) was 0.51, indicating a moderate effect. In conclusion, the administration of 200 g beetroot juice for 14 days was associated with a small but statistically significant increase in hemoglobin levels in patients with head and neck cancer who underwent chemotherapy. Further studies in the form of RCTs with larger sample sizes and stricter compliance monitoring are needed to confirm these findings and assess their clinical relevance.
Co-Authors Andini, Dena Tria Fadhlia Fitria, Sova Haroen, Elvia Kurnia , Benny Kurnia, Benny Oktaria Denantika Rachmad Suhanda Ridwan, Azwar Sinaga, Jakaria