Mangkoesoebroto, Arjatya Pramadita
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Kejadian Kardiovaskular Mayor di Rumah Sakit pada Pasien STEMI di Era Pandemi COVID-19 Mangkoesoebroto, Arjatya Pramadita; Herry, Yan; Sofia, Sefri Noventi; Bahrudin, Udin
Medica Hospitalia : Journal of Clinical Medicine Vol. 10 No. 1 (2023): Med Hosp
Publisher : RSUP Dr. Kariadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36408/mhjcm.v10i1.852

Abstract

BACKGROUND: The Coronavirus Disease 2019 (COVID-19) pandemic has become a global burden, changing healthcare system and affecting patients with ST segment elevation myocardial infarction (STEMI). Several countries reported a decrease in hospital admission, changing management, increase total ischemic time, and major cardiovascular events (MACE) in the pandemic era. However, there is limited data especially in Indonesia. OBJECTIVE: To know the differences in admissions, characteristics, management and in-hospital MACE in STEMI patients between pre and pandemic era. METHODS: Comparative observational analytical study was done on 169 patients in the pre-pandemic (12 March 2019-11 March 2020) compared to 163 patients in the pandemic era (12 March 2020-30 September 2021) with STEMI at dr. Kariadi Semarang Hospital. Assessment of monthly admission rates, total ischaemic time, reperfusion management, COVID-19 status and MACE were carried out. RESULTS: During the COVID-19 pandemic, there was a decrease in the average admission of 14.1 to 8.6 patients per month (p<0.001), increase total ischaemic time of 8.78 (3.22-19.68) hours to 10.22 (3 .20-20.43) hours (p<0.001), decreased use of primary PCI (97.0% vs. 83.4%, p<0.001), increased fibrinolytic (1.8% vs8.6%,p=0.010) and no reperfusion (1.2%vs8.0%, p=0.007). There was a significant increase in MACE in the era of the COVID-19 pandemic (10.7%vs22.1%,p=0.008), with mortality (4.7%vs11.7%,p=0.035), stroke (1.2%vs1.8%,p=0.680), cardiogenic shock (4.1%vs11.0%, p=0.030), and acute pulmonary edema (3.6%vs10.4%,p=0.024). CONCLUSION: There was a decrease in admissions and primary PCI procedure, increase use of fibrinolytics and without reperfusion, total ischemic time prolongation, and significant increase of in-hospital MACE in STEMI patients during the COVID-19 pandemic.
Electrocardiographic Pattern of Pregnant Women with Advanced Maternal Age Mangkoesoebroto, Arjatya Pramadita; Pramono, Besari Adi; Mochtar, Aruman Yudanto Ariwibowo Binarso
Diponegoro International Medical Journal Vol 4, No 1 (2023): July 2023
Publisher : Faculty of Medicine, Diponegoro University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/dimj.v4i1.15837

Abstract

Background: Advanced maternal age (AMA) is becoming increasingly common and is associated with increased maternal and fetal morbidity and mortality. Around 22,2% of maternal deaths were found to be from cardiovascular disease, and women with higher cardiovascular mortality were likely older. Electrocardiography (ECG) is a simple tool for detecting cardiovascular problems. Though there are many studies of the ECG in normal pregnant women, there is still limited data on the ECG pattern in pregnant women with AMA.Objective: Describe the characteristics of the ECG pattern in woman with AMA.Methods: This study used data retrospectively from medical records of patient in Kariadi General Hospital Semarang from 1st to 30th October 2018. The inclusion criteria were advanced age ³ 35 years,  in the last trimester. Demography, clinical, laboratory , and 12-lead ECG data were collected and reported.Results: Thirteen patients were obtained, with mean age of 38,3 years. Majority of patients had preeclampsia (61,5%) and superimposed preeclampsia (15,4%). Mean systolic blood pressure was 168 mmHg. All of the patients was sinus rhythm, with a mean heart rate 92,5 bpm. Mean QTc was 430,7ms, with 3 patients (23,1%) having borderline prolongation grade. Another abnormality was a left atrial abnormality in 3 patients (23,1%), poor R wave progression in 2 patients (15,4%), and a pathological Q wave in 1 patients (7,7%).Conclusion: ECG abnormalities are seen in 38,4% of pregnant women over 35 years old. The performance of an ECG in AMA may be a first step toward improved pregnancy outcomes since it is widely available and easily interpreted by general practitioners.
Simultaneous Acute Cardio-Cerebral Infarction: A Rare Case Report Experience in Type C Hospital in Indonesia Andriani, Nurlita Asri; Mangkoesoebroto, Arjatya Pramadita; Chairina Yuliandita, Rizkia; Pramudyo, Bayu Hendro
Indonesian Basic and Experimental Health Sciences Vol. 13 No. 2 (2025): APRIL
Publisher : Rumah Sakit Umum Daerah Dr. Moewardi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11594/ibehs.vol13iss2pp41-47

Abstract

Background: The simultaneous occurrence of ST-elevation myocardial infarction (STEMI) and acute ischemic stroke (AIS) was described as Cardio-Cerebral Infarction. Consequently, we aimed to provide an overview of the available treatment option for patients in type c hospital in order to guide the similar cases. Case Description: A 50-year-old man came to the emergency room complaining of chest pain for two hours before. The patient had a history of hypertension and an active smoker. The patient had a left hemiparesis. The patient's electrocardiogram showed ST segment elevation in leads V3 and V4. A non-contrast head CT-scan showed infarct in the right occipital region. Echocardiogram showed regional wall motion abnormality. The patient was admitted to the hospital, administered DAPT, statin, anticoagulant and discharged after relief of symptoms. Intravenous alteplase followed by primary PCI is the gold standard therapy. However, due to limitation, anticoagulants were chosen and showed clinical improvements. Conclusion: In summary, the goal for treat CCI is to achieve more efficacy therapy while minimising the risk of bleeding. Despite the limitations, patient outcome was good.