Article Per Year (5 Year)
p-Index From 2020 - 2025
2.461
P-Index
This Author published in this journals
All Journal Jurnal Kesehatan Masyarakat Journal of Biomedicine and Translational Research Indonesian Journal of Cardiology Journal Of Management Science (JMAS) Medica Hospitalia Jurnal Health Sains Narra J Balance : Jurnal Akuntansi dan Manajemen Journal of Vocational Studies on Applied Research Eduvest - Journal of Universal Studies
Udin Bahrudin, Udin
Unknown Affiliation
Aerospace Engineering Biochemistry, Genetics & Molecular Biology Computer Science & IT Decision Sciences, Operations Research & Management Dentistry Economics, Econometrics & Finance Engineering Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Veterinary

Published : 15 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 15 Documents
Search

 1   2 
Anthropometric-Parameters and Total-Cholesterol to HDL-Cholesterol Ratio are Better in Long-Distance Cyclists (Indonesia North Coast and Tour de Borobudur 2017 Study) Azam, Mahalul; Rahayu, Sri Ratna; Fibriana, Arulita Ika; Susanto, Hardhono; Kartasurya, Martha Irene; Bahrudin, Udin
KEMAS: Jurnal Kesehatan Masyarakat Vol 14, No 2 (2018)
Publisher : Department of Public Health, Faculty of Sport Science, Universitas Negeri Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15294/kemas.v14i2.14506

Abstract

Total-Cholesterol (TC) to HDL-Cholesterol (HDL-C) ratio in athletes is well-known to be better than sedentary people. However, information about comparison of TC/HDL-C in different groups of cyclists based on cycling touring characteristics and anthropometry parameters is lacking. This study aimed to compare TC/HDL-C ratio between groups based on the type of tour in cyclists population. Eighty-eight participants were recruited in this cross-sectional study. Mean differences of parameters between groups was analyzed by One-Way Anova and independent t-test, whereas multivariate analyses was conducted by binary logistic-regression. P value <0.05 was considered statistically significant. TC/HDL-C ratio in all groups were less than 4.5. There is no differences of TC-levels (NC240K: 216.6±55.04, TdB140K: 208.1±27.13, TdB100K: 203.1±31.95; p=0.427). But there is significantly different level of HDL-C (NC240K: 68.9±19.09, TdB140K: 52.1±13.9, TdB100K: 53.6±12.45; p=0.0001) and TC/HDL-C ratio (NC240K: 3.3±1.12, TdB140K: 4.2±1.07, TdB100K: 4.0±1.06; p=0.007). Between TC/HDL ratio groups (≥4 or <4), there were differences of weight, BMI, waist-circumference, hip-circumference and type of tour (p<0.05). Finally, BMI and type of tour were the most influential factor. Long-distance cyclists have a synergistic effect of lipid profile and anthropometry measurements, and heavier cycling tour participant, that represent cycling training habits, tend to have lower TC/HDL ratio(< 4).
Association between Neutrophil to Lymphocyte Ratio and Post Operative Atrial Fibrillation after Coronary Artery Bypass Graft operation. Sidiek, Aboesina; Herry, Yan; Ardhianto, Pipin; Bahrudin, Udin
Journal of Biomedicine and Translational Research Vol 10, No 1 (2024): April 2024
Publisher : Faculty of Medicine, Universitas Diponegoro

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/jbtr.v10i1.20804

Abstract

ABSTRACT Background: Post operative atrial fibrillation (POAF) is associated with cardiovascular outcomes such as stroke, heart failure, and mortality. Neutrophil to lymphocyte ratio (NLR) is one of biomarker of inflammation. The use of cor pulmonary bypass(CPB), surgical trauma and reperfusion injury during cardiac surgery causes inflammation. NLR is suspected to be a biomarker that represents the inflammatory response as a modulator of POAF, but data are still lacking.This study analyzed the association between NLR and POAF after coronary artery bypass graft (CABG) operation.Methods: This was an Observational analytic study, involving patients after the CABG procedure in Kariadi Hospital between June 2022 to September 2023. NLR was assessed in the first three hours after operation. ECG Holter was attained for 96 hours post-CABG procedure.Results: The total subject was 62 patients, consisting of 57 men and 5 women with a mean age of 58,7 ± 6.39 years. Mean postoperative NLR 4.95 ± 2.17 with a median of 4.56 (1.52-11.00). There was a significant association between post-operative NLR with POAF after CABG (p=0.006, OR 4.64, 95%CI 1.50-14.35). High inotropic dose and β blocker initiation time less than 45 hours correlate significantly with POAF after CABG (p<0.001, OR 6.94 dan p=0.001, OR 0.17).Conclusions: Postoperative NLR is associated significantly with POAF after CABG. Keywords: Neutrophil to Lymphocyte Ratio, Post Operative Atrial Fibrillation, coronary artery bypass graft, ECG Holter
PENGARUH EKSTRAK EDAMAME KAYA GENISTEIN TERHADAP KADAR LOW DENSITY LIPOPROTEIN, HIGH SENSITIVITY-C REACTIVE PROTEIN, SERTA RASIO NEUTROFIL LIMFOSIT DAN MONOSIT LIMFOSIT: Studi Experimental pada Tikus Jantan yang Diinduksi Aterosklerosis Pratama, Reza Dian; Maharani, Nani; Bahrudin, Udin
Medica Hospitalia : Journal of Clinical Medicine Vol. 8 No. 1 (2021): Med Hosp
Publisher : RSUP Dr. Kariadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (323.892 KB) | DOI: 10.36408/mhjcm.v8i1.450

Abstract

ABSTRACT Background: Atherosclerosis is related to hypercholesterolaemia and inflammation. Edamame is one of the soybeans with high levels of genistein which protects the formation of atherosclerosis. Purpose: This research aimed to evaluate the effects of genistein-rich edamame on LDL, hs-CRP, Neutrophil-Lymphocyte Ratio (NLR) and Monocyte-Lymphocyte Ratio (MLR) on atherosclerosis-induced mice. Method: This research is a true experimental study with posttest only-controlled group design. Thirty male rats were divided randomly into five groups: negative control group without any intervention, positive control group with atherosclerosis induction, first intervention group with edamame extract supplementation, second intervention group with genistein-rich edamame extract supplementation, and third intervention group treated with atorvastatin. After 28 days, serum LDL, hs-CRP, LDL and MLR were measured. Results: There were significant differences (p<0.001) of hs-CRP values between the second intervention group compared to the negative control, positive control and first intervention group. Edamame extract lowered LDL cholesterol levels in the second intervention group compared to positive control, but the difference were not statistically significant. There were significant differences (p<0.05) of MLR values between the second intervention group and the negative control and also the first intervention group, and significant differences between the second intervention group and the negative control and also the first intervention group. There was no significant difference on NLR values between all groups. Conclusion: The administration of genistein rich edamame may reduces the inflammation in the blood vessels better than edamame extract represented by lower hs-CRP and MLR values compared to the edamame extract. Keywords: Genistein rich-edamame, LDL, hsCRP, neutrophil-lymphocyte ratio, monocyte-lymphocyte ratio
Korelasi Antara Jumlah Cd4 Dengan Global Longitudinal Strain Ventrikel Kiri Pada Penderita Human Immunodeficiency Virus Pratama, Yanuar Surya; Chairunnisa, Andita; Bahrudin, Udin; Uddin, Ilham; Nugroho, Mochamad Arif; Sofro, Muchlis Achsan Udji; Kristina, Tri Nur
Medica Hospitalia : Journal of Clinical Medicine Vol. 8 No. 1 (2021): Med Hosp
Publisher : RSUP Dr. Kariadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (316.326 KB) | DOI: 10.36408/mhjcm.v8i1.495

Abstract

Latar Belakang: Jumlah CD4 merupakan parameter penting pada penderita HIV dan berhubungan dengan peningkatan risiko disfungsi sistolik. Hingga saat ini, korelasi antara jumlah CD4 dengan parameter global longitudinal strain (GLS) sebagai indikator fungsi sistolik subklinis masih belum jelas. Metode: Penelitian ini merupakan studi observasional dengan metode belah lintang. GLS ventrikel kiri diperiksa menggunakan ekokardiografi dua dimensi. Jumlah CD4 baseline dan nadir diperoleh dari rekam medis sedangkan jumlah CD4 aktual dan CD4 percentage (CD4%) diperiksa menggunakan metode flow cytometry. Hasil: Total 37 pasien HIV asimptomatik mengikuti penelitian dengan rerata umur 31,95± 7,54 tahun dan median durasi penggunaan ARV adalah 34 bulan. Median CD4 baseline dan CD4 nadir adalah 272 sel/uL dan 223 sel/uL, sedangkan rerata CD4 aktual dan CD4% adalah 516,08±252,03 sel/uL dan 19,66±7,97 %. Semua subyek penelitian memiliki fungsi sistolik normal. Rerata GLS ventrikel kiri adalah 17,02±0,71. GLS ventrikel kiri berkorelasi positif dengan CD4 aktual (r=0,43; p=0,008) dan CD4% (r=0,349; p=0,034). Penderita HIV dengan jumlah CD4 aktual ?400 sel/uL memiliki GLS ventrikel kiri yang lebih baik dibandingkan dengan yang <400 sel/uL (p=0,022). Kesimpulan: Jumlah CD4, terutama CD4 aktual dan CD4 percentage berkorelasi dengan disfungsi sistolik subklinis yang diukur dengan global longitudinal strain pada penderita HIV asimtomatik. Hal ini mungkin dapat menjelaskan peran CD4 terhadap patogenesis gagal jantung pada penderita HIV.
Aspirasi Trombus Selektif Memperbaiki Aliran Koroner dan Mengurangi Tingkat Badai Trombus pada Pasien Sindroma Koroner Akut Dengan Elevasi Segmen ST yang dilakukan Intervensi Koroner Perkutan Primer Bramantyo, Liborius; Bahrudin, Udin; Ardhianto, Pipin; Uddin, Ilham; Rifqi, Sodiqur
Medica Hospitalia : Journal of Clinical Medicine Vol. 8 No. 3 (2021): Med Hosp
Publisher : RSUP Dr. Kariadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (286.685 KB) | DOI: 10.36408/mhjcm.v8i3.583

Abstract

Latar belakang: Embolisasi distal koroner berkontribusi terhadap tingginya kejadian kardiovaskular mayor (KKVM) pasca intervensi koroner perkutan primer (IKPP). Aspirasi trombus (AT) manual berpotensi mengurangi embolisasi distal dan memperbaiki perfusi mikrovaskular pada pasien sindroma koroner akut dengan elevasi segmen ST (SKA-EST), terutama pasien dengan badai trombus tinggi. Tujuan: Mengetahui pengaruh aspirasi trombus selektif terhadap skor TIMI trombus dan luaran klinis pasca IKPP. Metode: Penelitian retrospektif pada pasien SKA-EST dengan onset ?12 jam dan skor trombus TIMI awal ?3 yang menjalani IKPP dengan aspirasi trombus selektif di RSUP Dr. Kariadi periode Januari 2018 sampai Desember 2019. Luaran klinis yang diobservasi adalah KKVM selama rawat inap yang terdiri dari mortalitas, syok kardiogenik, edema paru akut, aritmia, revaskularisasi ulang, dan stroke. Hasil: Sejumlah 100 pasien memenuhi kriteria, terdiri dari 50 pasien kelompok AT dan 50 pasien kelompok non-AT. Rerata skor trombus TIMI awal kelompok AT dan non-AT, masing-masing 4,76 dan 3,8 (p<0,001). Kelompok AT mengalami penurunan skor trombus TIMI lebih baik dibanding non-AT (4,72 vs. 3,8, p<0,001). Terdapat 8 (16%) pasien kelompok AT dan 11 (22%) pasien non-AT yang mengalami KKVM pasca IKPP (RR 1,08, IK 95% 0,89-1.30, p=0,44). Kesimpulan: Aspirasi trombus selektif mungkin mengurangi tingkat badai thrombus. Aspirasi trombus mungkin menurunkan kejadian kardiovaskular mayor selama rawat inap pasca IKPP pada pasien dengan skor trombus TIMI di atas 4 setara dengan yang memiliki skor trombus TIMI kurang dari 4 tanpa aspirasi trombus.
Pemberian Krim Ekstrak Moringa oleifera L. pada Tikus dengan Luka Insisi: Studi terhadap Kadar IL-1, IL-10 dan rasio IL-1:IL-10: The Application of Moringa oleifera L. Cream on Rats with Incision Wound: Study on the IL-1 Level, IL-10 Level and IL-1:IL-10 ratio Surya Utoyo, Frederick; Bahrudin, Udin; Prajoko, Yan Wisnu; Mahati, Endang; Maharani, Nani
Medica Hospitalia : Journal of Clinical Medicine Vol. 9 No. 3 (2022): Med Hosp
Publisher : RSUP Dr. Kariadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36408/mhjcm.v9i3.778

Abstract

LATAR BELAKANG : Saat ini, berbagai tanaman asli Indonesia dikembangkan sebagai bahan perawatan luka untuk hasil penyembuhan yang lebih baik. Salah satunya, yaitu Moringa oleifera L., yang  merupakan tanaman asli Indonesia serta berpotensi dapat membantu penyembuhan luka  melalui regulasi jalur sitokin inflamasi, interleukin (IL)-1 dan IL-10. TUJUAN : Untuk mengetahui pengaruh pemberian ekstrak Moringa oleifera L. terhadap IL-1, IL-10, dan rasio IL-1: IL-10 di jaringan kulit, pada tikus dengan luka insisi. METODE : Penelitian ini menggunakan desain post test only controlled group dengan sampel berupa 15 tikus Wistar yang dilakukan luka insisi. Sampel dibagi menjadi 3 kelompok perlakuan: perawatan luka dengan framycetin sulphate (KP), krim ekstrak Moringa oleifera L. 15% (M), dan krim plasebo (KN). Pengukuran kadar IL-1, IL-10, dan rasio IL-1:  IL-10 dilakukan pada hari ke-10 perlakuan melalui pengambilan jaringan. HASIL :  Kadar IL-1 pada kelompok perlakuan (M) tidak berbeda bermakna dibanding KN dan KP (33,56±4,68 vs 40,92±27,32 vs 30,23±3,92 pg/mL, p=0,543). Kelompok KP memiliki IL-10 lebih tinggi dibandingkan kelompok M dan KN (113,95±9,38; 91,75±5,65 dan 94,93±2,39 pg/mL, p<0,001), dan tidak didapatkan perbedaan antara kelompok M dan KN (p=0,296). Rasio IL-1: IL-10 kelompok KP, M, dan KN tidak menunjukan perbedaan bermakna (0,27±0,05, 0,37±0,06 dan 0,44±0,30, p=0,249). KESIMPULAN: Pemberian ekstrak Moringa oleifera L. secara topikal tidak mempengaruhi kadar IL-1 dan rasio IL-1 : IL-10 di jaringan kulit tikus dengan luka insisi. Kadar IL-10 di jaringan kulit tidak berbeda dibanding kelompok kontrol negatif, serta lebih rendah dibanding kelompok framycetin sulphate. KATA KUNCI           : Luka insisi, Moringa oleifera L., perawatan luka
Kejadian Kardiovaskular Mayor di Rumah Sakit pada Pasien STEMI di Era Pandemi COVID-19 Mangkoesoebroto, Arjatya Pramadita; Herry, Yan; Sofia, Sefri Noventi; Bahrudin, Udin
Medica Hospitalia : Journal of Clinical Medicine Vol. 10 No. 1 (2023): Med Hosp
Publisher : RSUP Dr. Kariadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36408/mhjcm.v10i1.852

Abstract

BACKGROUND: The Coronavirus Disease 2019 (COVID-19) pandemic has become a global burden, changing healthcare system and affecting patients with ST segment elevation myocardial infarction (STEMI). Several countries reported a decrease in hospital admission, changing management, increase total ischemic time, and major cardiovascular events (MACE) in the pandemic era. However, there is limited data especially in Indonesia. OBJECTIVE: To know the differences in admissions, characteristics, management and in-hospital MACE in STEMI patients between pre and pandemic era. METHODS: Comparative observational analytical study was done on 169 patients in the pre-pandemic (12 March 2019-11 March 2020) compared to 163 patients in the pandemic era (12 March 2020-30 September 2021) with STEMI at dr. Kariadi Semarang Hospital. Assessment of monthly admission rates, total ischaemic time, reperfusion management, COVID-19 status and MACE were carried out. RESULTS: During the COVID-19 pandemic, there was a decrease in the average admission of 14.1 to 8.6 patients per month (p<0.001), increase total ischaemic time of 8.78 (3.22-19.68) hours to 10.22 (3 .20-20.43) hours (p<0.001), decreased use of primary PCI (97.0% vs. 83.4%, p<0.001), increased fibrinolytic (1.8% vs8.6%,p=0.010) and no reperfusion (1.2%vs8.0%, p=0.007). There was a significant increase in MACE in the era of the COVID-19 pandemic (10.7%vs22.1%,p=0.008), with mortality (4.7%vs11.7%,p=0.035), stroke (1.2%vs1.8%,p=0.680), cardiogenic shock (4.1%vs11.0%, p=0.030), and acute pulmonary edema (3.6%vs10.4%,p=0.024). CONCLUSION: There was a decrease in admissions and primary PCI procedure, increase use of fibrinolytics and without reperfusion, total ischemic time prolongation, and significant increase of in-hospital MACE in STEMI patients during the COVID-19 pandemic.
The role of social media in creating brand awareness and purchase intention Kurniasih, Dedeh; Alam, Surya; Bahrudin, Udin
Junal Ilmu Manajemen Vol 8 No 1 (2025): January: Management Science and Field
Publisher : Institute of Computer Science (IOCS)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35335/jmas.v8i1.635

Abstract

Social media has become an integral part of modern marketing strategies, offering a powerful platform for businesses to connect with their target audience. The rise of social media platforms has revolutionized the way companies interact with consumers, which has a significant impact on brand awareness and purchase intent. The purpose of this study is to test and analyze the role of social media in creating brand awareness and purchase intention. The research method used is a SEM-PLS-based causality approach. The sample used was Nako Coffee consumers with a total of 100 respondents using the Lameshow formula. The results of this study provide an explanation that social media has a strong influence on brand awareness and purchase intention, and at the same time brand awareness can be a mediator in social media on purchase intention.
Role of phosphodiesterase-3 inhibitor in cardiorespiratory fitness and functional class of patients with pulmonary hypertension: A randomized, double-blind, placebo-controlled trial Sofia, Sefri N.; Bahrudin, Udin; Uddin, Ilham; Sobirin, Muhammad A.; Setiawati, Erna; Hardiningsih, Galuh; Tjandra, Kevin C.; Limijadi, Edward KS.
Narra J Vol. 5 No. 1 (2025): April 2025
Publisher : Narra Sains Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52225/narra.v5i1.1301

Abstract

Many patients with acyanotic shunt congenital heart disease (CHD) are diagnosed only in adulthood, by which time pulmonary hypertension (PH) has developed, impairing their functional class and cardiorespiratory fitness. While PH treatments are limited and expensive, cilostazol, a phosphodiesterase-3 inhibitor, has shown potential in reducing pulmonary artery pressure and improving heart function, offering hope for better patient outcomes. The aim of this study was to evaluate the effects of cilostazol on cardiorespiratory fitness and functional class in patients with acyanotic shunt CHD with PH using a randomized, double-blind, placebo-controlled trial. The trial was conducted at Dr. Kariadi Hospital, Semarang, Indonesia, from March 2022 to March 2023. Patients aged 14–75 years were randomly assigned to receive cilostazol (initially 200 mg, later adjusted to 100 mg) or placebo for three months. Cardiorespiratory fitness was assessed using the six-minute walk test (6MWT) and VO2 max at pre-intervention and three months post-intervention. After three months, the mean 6MWT was not significantly different between cilostazol and placebo groups (319.65±50.52 vs 317.65±45.26 meters; p=0.090). Similarly, the VO2 max was also not significantly different between cilostazol and placebo groups (10.74±2.59 mL/kg/min vs 10.73±2.8 mL/kg; p=0.099). However, the percentage of patients who had functional class improvement was significantly higher in the cilostazol group compared to the placebo group (90% vs 30%; p<0.001). This study indicated that cilostazol could improve functional class in acyanotic shunt CHD patients with PH. However, larger and more robust trials are warranted to confirm the potential benefits of cilostazol in this patient population.
Optimization On Subcritical Fluid Extraction Of Zingiberene Paramita, Vita; Yulianto, Mohamad Endy; Hartati, Indah; Bahrudin, Udin; Broto, R. T. D. Wisnu
Journal of Vocational Studies on Applied Research Volume 1, Issue 1, Year 2019 (April 2019)
Publisher : Vocational College of Universitas Diponegoro

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (769.451 KB) | DOI: 10.14710/jvsar.v1i1.4292

Abstract

The establishment of subcritical fluid application for zingiberene extraction was studied by employing water as a green solvent. The zingiberene content was observed by using Liquid Chromatography-Mass Spectrofotometry and regarding to the independent variable of temperature, extraction time, ginger-solvent ratio and aging time. By applying subcritical water, the critical value of zingiberene content obtained was 0.036%. This value was approached by the surface modeling of alpha for rotatability design which performed at 125 oC, 20 min of extraction time, 0.08 of ginger to solvent ratio and 9 min of aging time of extraction parameters. The surface modeling was validated by plotting the observed and predicted value of zingiberene content and evidenced by the value of R-square at 0.76.
Co-Authors ABOESINA SIDIEK Ahmad Solihin Alam, Surya Arulita Ika Fibriana Asrial, An Aldia Bramantyo, Liborius Broto, R. T. D. Wisnu Chairunnisa, Andita Dedeh Kurniasih Endang Mahati Erna Setiawati, Erna Handayani, Eri Hardhono Susanto Hardiningsih, Galuh Herry, Yan Hisatome, Ichiro Ilham Uddin Indah Hartati Kuwabara, Masanari Li, Peili Limijadi, Edward KS. Mahalul Azam Mangkoesoebroto, Arjatya Pramadita Martha Irene Kartasurya Mochamad Arif Nugroho Mohamad Endy Y Yulianto Muchlis Achsan Udji Sofro Nani Maharani Ninomiya, Haruaki Pipin Ardhianto, Pipin Pratama, Reza Dian Pratama, Yanuar Surya Pudjiastuti, Anggit Rahima Rahima Rostika Flora Rr. Sri Ratna Rahayu Sefri Noventi Sofia Sembiring, Edy Suranta Karina Sobirin, Muhammad A. Sodiqur Rifqi Sofia, Sefri N. SUKENDRO SUKENDRO, SUKENDRO Surya Utoyo, Frederick Taufiq, Fikri Tjandra, Kevin C. Tri Nur Kristina Vita Paramita Yan Wisnu Prajoko