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All Journal Jurnal Ilmiah Cendekia Eksakta Sinteza Jurnal Farmasi Sains dan Terapan (Journal of Pharmacy Science and Practice)
Devi, Sisca
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Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Health Professions Immunology & microbiology Mechanical Engineering Medicine & Pharmacology

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Journal : Sinteza

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Pengaruh Perbedaan Konsentrasi Propilenglikol terhadap Karakteristik Fisik Hair Tonic Ekstrak Daun Katuk (Sauropus androgynus (L). Merr) Daradasih, Elline; Devi, Sisca
Sinteza Vol. 3 No. 2 (2023): August
Publisher : Universitas Hamzanwadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29408/sinteza.v3i2.16825

Abstract

Katuk leaf extract contains flavonoids which can stimulate hair growth by relaxing the muscles in the blood vessels around the hair follicles. One dosage form that is suitable for hair growth application is hair tonic preparations. An important component in the formulation of hair tonic is a thickener which can maintain the stability of the preparation. Propylene glycol is a thickening agent that can determine the physical characteristics of hair tonic preparations which are related to the stability of the resulting preparations. The purpose of this study was to determine the effect of different concentrations of propylene glycol on the physical characteristics of hair tonic katuk leaf extract (Sauropus androgynus (L.) Merr). This type of experimental research uses a completely randomized design (CRD) one factorial. The independent variables in this study were the concentration of propylene glycol 5%, 15% and 25%. Testing the physical characteristics of hair tonic preparations included organoleptic, clarity, pH, viscosity, and specific gravity. Data analysis used the ANOVA test with a 95% level of confidence then continued with the Post hoc test. The results of the physical characteristic test showed that the difference in the concentration of propylene glycol in hair tonic katuk leaf extract had an effect on the physical characteristics of viscosity (p<0.05).
Pengaruh Konsentrasi Karbopol sebagai Emulgator terhadap Karakteristik Fisik Sediaan Lotion Ekstrak Daun Belimbing Wuluh (Averrhoa bilimbi L.) Palma, Retno Dela; Devi, Sisca
Sinteza Vol. 5 No. 1 (2025): February
Publisher : Universitas Hamzanwadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29408/sinteza.v5i1.27305

Abstract

Starfruit leaf extract produces antioxidant activity from the flavonoid compound content. The lotion dosage form is one of the dosage forms used as an antioxidant application to the skin. The lotion formula consists of a water phase, an oil phase, and an emulsifier. The emulsifier is the most important part of the formation of lotion because it determines the physical characteristics produced and the stability of the preparation. Carbopol is a synthetic emulsifier that can absorb liquid and form a stable mass to produce stable physical characteristics of the lotion. The purpose of this study was to influence the concentration of carbopol on the physical attributes of starfruit leaf extract lotion and to determine the concentration of carbopol with the best physical characteristics of starfruit leaf extract lotion. This study is an experimental study with different concentrations of Carbopol, namely 0.3%; 0.4%; and 0.5%. The physical characteristics measured were organoleptic, pH, homogeneity, viscosity, spreadability, adhesion, protection power, and emulsion type. Viscosity and adhesion test data were tested using Kruskal Wallis and continued with Mann Whitney, while spreadability and protection test data were tested using ANOVA followed by Pos Hoc. The results showed that increasing the concentration of Carbopol affected protection power (p<0.05). The concentration of Carbopol that produced the best characteristics was 0.3% (formula 1).
Co-Authors Baiti, Hilma Nur Daradasih, Elline Palma, Retno Dela Widiyana, Widiyana