Article Per Year (5 Year)
p-Index From 2020 - 2025
0.444
P-Index
This Author published in this journals
All Journal Jurnal Ilmu Kefarmasian Indonesia Journal Pharmasci (Journal of Pharmacy and Science)
Yunitasari, Fitria Dewi
Unknown Affiliation
Biochemistry, Genetics & Molecular Biology Chemistry Health Professions Immunology & microbiology Medicine & Pharmacology Public Health

Published : 4 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 4 Documents
Search

 1 
Prescribed Daily Dose (PDD) Antibiotik Untuk Penyakit Gigi di Salah Satu Apotek di Surabaya Zulfa, Ilil Maidatuz; Yunitasari, Fitria Dewi
Journal of Pharmacy and Science Vol. 2 No. 2 (2017): Journal of Pharmacy and Science
Publisher : Akademi Farmasi Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53342/pharmasci.v2i2.77

Abstract

ABSTRAKAntibiotik sistemik banyak diresepkan oleh dokter gigi baik sebagai profilaksis maupun penanganan infeksi. Tingginya peresepan antibiotik pada infeksi gigi dan periodontal akan berpotensi pada peningkatan resistensi bakteri karena penggunaan yang berlebihan. Tujuan dari penelitian ini adalah untuk menginvestigasi pola peresepan, Prescribed Daily Dose (PDD) dan rasio PDD/DDD yang ditetapkan WHO setiap antibiotik yang diresepkan untuk penyakit gigi. Studi cross-sectional retrospektif dilakukan pada rekam resep tahun 2016 di salah satu Apotek di Surabaya. Sebanyak 136 resep untuk penyakit gigi telah dianalisis dalam penelitian ini. Rata-rata usia pasien adalah 38,92+12,96 tahun. Antibiotik yang paling banyak diresepkan adalah Golongan –Laktam yaitu Amoksisilin (50,72%) dan Amoksisilin+Asam Klavulanat (3,62%) diikuti oleh golongan Linkosamid yaitu Klindamisin (28,99%) dan Linkomisin (5,80%), serta golongan Nitroimidazol yaituMetronidazol (5,07%). PDD Antibiotik yang diresepkan lebih rendah dibanding DDD yang ditetapkan WHO kecuali Amoksisilin (1509,2 mg/pasien/hari; rasio PDD/DDD 1,59), Amoksisilin+Asam Klavulanat (1368,42 mg/pasien/hari; rasio PDD/DDD 1,37), Eritromisin (1500,00 mg/pasien/hari; rasio PDD/DDD 1,50), dan Levofloksasin (500,00 mg/pasien/hari; rasio PDD/DDD 1,00). Terdapat perbedaan antara nilai PDD beberapa antibiotik dengan nilai DDD yang ditetapkan WHO dimana dalam penelitian ini nilai PDD lebih merefleksikan densitas penggunaan antibiotik.Kata kunci: Prescribed Daily Dose (PDD), Antibiotik, Infeksi gigi.ABSTRACTSistemic Antibiotics are prescribed by dentists not only for treatment of infection but also for profilactics. Most of dental and periodontal diseases are best treated by operative intervention and oral hygiene measures, so that the use of sistemic antibiotics are very limited. High rates of sistemic antibiotics prescribing in densitry can lead to bacterial resistance due to overuse of antibiotics. The aim of the study was to investigate the antibiotics prescribing patterns in densitry, Prescribed Daily Dose (PDD), and PDD/WHO’s Defined Daily Dose (DDD) ratio. A retrospective cross-sectional study was conducted on 2016 prescription records at a private pharmacy in Surabaya, East Java, Indonesia. A total 136 prescription records were analyzed. The average age of patients was 38,92+12,96 years old. The most common antibiotics prescribed in densitry was –Lactam group which were Amoxycillin (50,72%) and Amoxycillin+Clavulanic Acid (3,62%) followed by Linkosamide group w Clindamycin (28,99%) and Lincomycin (5,80%), and Nitroimidazol group which was Metronidazole (5,07%). The PDD of Antibiotics prescribed was lower than each WHO’s DDD except Amoxycillin (1509,2mg/patient/day; PDD/DDD ratio 1,59), Amoxycillin+Clavulanic Acid (1368,42 mg/patient/day; PDD/DDD ratio 1,37), Eritromisin (1500,00 mg/patient/day; PDD/DDD ratio 1,50), dan Levofloksasin (500,00 mg/patient/day; PDD/DDD ratio 1,00). There was a difference between PDD and WHO’s DDD. PDD was more likely reflect the density of antibiotic usage. Key Words: Prescribed Daily Dose (PDD), Antibiotics, Dental Infections
Hospitalisasi Pasien Skizofrenia di Rumah Sakit Jiwa Menur Surabaya Yunitasari, Fitria Dewi; Zulfa, Ilil Maidatuz
Journal of Pharmacy and Science Vol. 3 No. 2 (2018): Journal of Pharmacy and Science
Publisher : Akademi Farmasi Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53342/pharmasci.v3i2.118

Abstract

ABSTRAKSkizofrenia merupakan gangguan atau kumpulan gangguan mental yang mempengaruhi pemikiran, persepsi, dan perilaku sosial dan penyebabnya sebagian besar masih belum diketahui. Pengobatan farmakologis skizofrenia menggunakan obat-obat golongan antipsikotik terutama dalam jangka waktu lima tahun setelah episode akut pertama muncul. Penggunaan antipsikotik berpotensi menimbulkan kejadian hospitalisasi yang dapat menurunkan kualitas hidup pasien terkait penurunan fungsi sosial pasien skizofrenia. Penelitian ini bertujuan menganalisis potensi jenis kelamin dan jenis pengobatan antipsikotik sebagai faktor prediktor hospitalisasi pasien skizofrenia. Analisis cross sectional jenis kelamin dan penggunaan antipsikotik dilakukan pada rekam medis pasien rawat inap di Rumah Sakit Jiwa Menur Surabaya Bulan Oktober 2017 yang didiagnosis skizofrenia (ICD-10 F20). Faktor prediktor hospitalisasi pasien  dianalisis menggunakan uji Chi-square for goodness of fit yang membandingkan perbedaan jumlah frekuensi antar kategori pada masing-masing faktor prediktor. Faktor jenis terapi antipsikotik digolongkan menjadi tipikal, atipikal, dan kombinasi. Hasil menunjukan terdapat perbedaan jumlah pasien pada tiga jenis terapi yang berbeda (p-value 0,000) dimana sebagian besar pasien yang dirawat dirumah sakit menerima antipsikotik tipikal (47,41%). Perbandingan jenis kelamin tidak menunjukkan perbedaan yang signifikan pada pasien yang dirawat. Dapat disimpulkan jenis antipsikotik tipikal kemungkinan dapat mempengaruhi kejadian hospitalisasi pada pasien skizofrenia. Kata kunci: Skizofrenia, antipsikotik tipikal, antipsikotik atipikal, hospitalisasi.ABSTRACTSchizophrenia is a mental disorder that affect thought, perception, and social behaviours. Most of causes of schizophrenia are unknown. Pharmacological treatments of schizophrenia use antipsychotics especially during  five years after first acute episode observed. The use of antipsychotics potentially lead to hospitalization that can affect to patients’ quality of life. This study was aimed to analyze the potential of gender and types of antipsychotic treatments as predictor factors in hospitalization of schizophrenia patients. Cross sectional analysis in gender and types of antipsycotics was conducted to medical records of inpatients at Rumah Sakit Jiwa Menur Surabaya diagnozed with Schizophrenia (ICD-10 Code F20) in October 2017. Chi-square for goodness of fit test was used to determine the difference amount of patients among different gender and different types of antipsychotics used as predictor factors. Types of antipsychotics used was classified into three categories which were patients who received typical antipsychotic, atypical antipsycotic and combination. The results showed that there was a significant difference in amount of hospitalized patients who received typical antipsychotic, atypical antipsycotic and combination (p-value 0,000) which most of hospitalized patients received atypical antipsychotics (47,41%).On the other hand, the proportion of gender among hospitalized patients was found have no significant difference. In conclusion, types of antipsychotics used might related to the hospitalization of schizophrenia patients.Keywords: Schizophrenia, Typical antipsychotic, Atypical antipsychotic, Hospitalization.
Evaluasi Peresepan Terapi Bronkopneumonia Anak di Unit Rawat Jalan Rumah Sakit Umum Daerah Bangkalan, Indonesia Zulfa, Ilil Maidatuz; Yunitasari, Fitria Dewi; Ratnadi, Nisa Dwi
Journal of Pharmacy and Science Vol. 4 No. 2 (2019): Journal of Pharmacy and Science
Publisher : Akademi Farmasi Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53342/pharmasci.v4i2.138

Abstract

ABSTRAKBronkopneumonia adalah salah satu manifestasi klinik dari pneumonia yang paling sering muncul pada anak. Obat yang diresepkan seringkali mengkombinasikan antibiotik dengan obat-obat simtomatis dan tidak sedikit yang berupa polifarmasi. Peresepan polifarmasi berpotensi pada kurang efisiennya pengobatan. Peresepan yang kurang efisien akan berakibat pada efektivitas dan keamanan terapi, eksaserbasi atau perpanjangan gejala dan penyakit, serta tingkat keamanan pada pasien, serta peningkatan biaya terapi. Tujuan dari penelitian ini adalah untuk mengevaluasi peresepan terapi bronkopneumonia pada anak. Studi observasional secara retrospektif dilakukan pada peresepan bronkopneumonia anak usia 0-14 tahun di Unit Rawat Jalan Rumah Sakit Umum Daerah Syarifah Ambami Rato Ebu Bangkalan, Indonesia selama tahun 2016. Evaluasi peresepan mengacu pada WHO prescribing indicator yang terdiri dari 5 poin. Hasil evaluasi pada penelitian ini menunjukkan bahwa rata-rata jumlah obat yang diresepkan adalah 4,60 item per kunjungan, obat generik diresepkan sebanyak 53,88%, antibiotik sebesar 69,31%, obat injeksi sebesar 0,99%, dan obat dalam Formularium Nasional tahun 2017 sebesar 48,28% dalam satu tahun periode peresepan. Sehingga, terdapat empat indikator yang belum sesuai dengan yang ditentukan WHO. Walaupun pemberian antibiotik sangat disarankan pada terapi bronkopneumonia, peresepan antibiotik masih memerlukan evaluasi lebih lanjut terkait rasionalitasnya. Selain itu, rendahnya peresepan berdasarkan Formularium Nasional tahun 2017 menunjukkan masih relatif rendahnya optimasi penggunaan obat yang cost-effective menurut kebijakan nasional.Kata kunci: Bronkopneumonia, Peresepan, Rawat Jalan.ABSTRACTBronchopneumonia is one of pneumonia manifestations commonly occur in children.The treatments usually combine antibiotics and symptomatic drugs in the form of polypharmacy.Polypharmacy can leads to inefficient treatmentsthat can cause ineffective and unsafe treatment, exacerbation or prolongation of illness, distress, harm to the patient and increasing the cost therapy.The aim of the study was to evaluate the prescribing for bronchopneumonia treatment in children. A retrospective observational study was conducted on prescriptions written for children with bronchopneumonia age 0-14 y.o in outpatient departement of Rumah Sakit Umum Daerah Syarifah Ambami Rato Ebu Bangkalan, Indonesia during 2016.WHO prescribing indicators was used to evaluate the prescribing. The result showed that the average number of medicine per encounter was 4.60 items, including medicine prescribed by generic name was 53.88%, antibiotics prescribed was 69.31%, injection prescribed was 0.99%, and medicines prescribed from National Formulary 2017 was 48.28%. Hence, there were four indicators found to be innapproppriate to WHO recomendation. Although antibiotics are highly recommended in bronchopneumonia, the usage of antibiotics still need an assessment related to its rationality. In addition, low percentage of medicines National Formulary showed low usage of cost-effective drugs based on the goverments policy.Keywords: Bronchopneumonia, Prescribing, Outpatients.
Association of side effects to medication adherence of antiepileptic drug use in epileptic patients Ernawati, Iin; Wyono, Oktaviani Putri; Yunitasari, Fitria Dewi; Pradani, Erwindy Yastika; Islamiyah, Wardah Rahmatul
JURNAL ILMU KEFARMASIAN INDONESIA Vol 22 No 1 (2024): JIFI
Publisher : Faculty of Pharmacy, Universitas Pancasila

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35814/jifi.v22i1.1269

Abstract

Epilepsy is a chronic neurological disorder with symptoms characterized by seizures, arising spontaneously with brief episodes with the main symptom of decreased or loss of consciousness. This study aims to examine the effect of side effects of medication adherence to antiepileptic drug use in epilepsy patients. This research is an observational study that was analyzed using quantitative descriptive methods in Neurology patients at the Airlangga University Hospital from March until May 2022. Side effects were measured using the LAEP (Liverpool Adverse Effects Profile) questionnaire and adherence was measured using a pill count. Results showed that the influence of side effects on medication adherence (pill count method) to antiepileptic drugs using linear regression, it is known that the P-value is 0.501. There is no significant relationship between the category of side effects and medication adherence to antiepileptic drugs. Another factor that influences compliance with medication use is the appearance of seizures. Based on the results of this study, it is known that the greater the frequency of seizures, the more likely patients are to be non-compliant (P-value 0.006). To increase adherence, it is necessary to pay attention to other factors such as knowledge, economy, and type of therapy in epilepsy patients so that therapeutic outcomes can be achieved.
Co-Authors Ernawati, Iin Islamiyah, Wardah Rahmatul Ni Made Dwi Ratnadi Pradani, Erwindy Yastika Wyono, Oktaviani Putri Zulfa, Ilil Maidatuz